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    Engaging Students in Pharmacogenetics: Patient Case Studies Using the PharmGKB Website
    Cytochrome P450 (CYP) enzymes are important regulators of drug efficacy and toxicity. Genetic variation in CYP isoforms can impact how well patients respond to medications or experience unwanted...

    Keywords: toxicologyPharmacologydrug metabolismpharmacodynamicspharmacogenetics

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    2007-Hui_Luo-Population Modeling by Differential Equations
    A general model for the population of Tibetan antelope is constructed. The present model shows that the given data is reasonably logistic.

    Keywords: population dynamicsextinctionlogisticTibetan antelope

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    2006-Graves-Peckham-Pastor-2D differential equations model for mutualism
    We develop from basic principles a two-species differential equations model which exhibits mutualistic population interactions.

    Keywords: population dynamicsLotka-Volterragrowth ratemutualismLichen

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    1-125-DiceyPopulation-ModelingScenario
    We offer students an opportunity to generate data for their team on a death and immigration model using 12 and 20 sided dice and then pass on the data to another student team for analysis with a...

    Keywords: simulationimmigrationdeathdice

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    1-025-MixingItUp-ModelingScenario
    Students build three different models for levels of salt in a tank of water and at each stage the level of complexity increases with attention to nuances necessary for success.

    Keywords: compartmentsalttankmixing

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    2006-Cooke-Elderkin-Huang-Predator-Prey interactions with delays due to juvenile maturation
    This paper focuses on predator-prey models with juvenile/mature class structure for each of the predator and prey populations in turn, further classified by whether juvenile or mature individuals...

    Keywords: predator-preyhost-parasitebifurcationage structrematuration delay

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    2005-P_Howard-Modeling with ODE
    In these notes we consider three critical aspects in the theory of ordinary differential equations: developing models of physical phenomena, mathematically well-posed, solving ODE numerically .

    Keywords: Fluid Mechanicscompartmentpopulationsvariational methodsHamiltonian mechanics

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    2005-Minna_Wedenberg-Pharmacokinetic modeling of gastric emptying
    The development of new drug substances is a complex, time consuming and expensive process. Reducing the time for drug development and avoiding late termination of candidate drugs are important...

    Keywords: paracetamolpharmacokineticsstomachsmall intestinesulfapyridine

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    2005-DieboldEtAl-Modeling Bond Yields In Finance And Macroeconomics
    From a macroeconomic perspective, the short-term interest rate is a policy instrument under the direct control of the central bank. From a finance perspective, long rates are risk-adjusted averages...

    Keywords: financeinterest ratebond yieldmacroeconomics

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    2004-Hill-Lozowski-Sampson-Experiments on ice spikes and a simple growth model
    We observed ice-spike growth using time-lapse digital photography, using two water types in two different containers.

    Keywords: iceice spikebulk heat transfermass conservation

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    2003-Yildirim-Mackey-Feedback Regulation in the Lactose Operon
    A mathematical model for the regulation of induction in the lac operon in Escherichia coli is presented.

    Keywords: mRNAlactoselactose operonfeedback regulation

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    2002-Nelson-Perelson-Mathematical analysis of delay differential equations models of HIV-1 infection
    We develop and analyze a set of models that include intracellular delays, combination antiretroviral therapy, and the dynamics of both infected and uninfected T cells.

    Keywords: infectionHIVT cells

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    2000-Idels-Wang-Harvesting Fisheries Management Strategies With Modified Effort Function
    This study concludes that a control parameter beta (the magnitude of the effect of the fish population size on the fishing effort function E), changes not only the rate at which the population goes...

    Keywords: sustainabilityfishFishingmanagementharvestfisherstrategyoverfishing

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    2016-Rob_deBoer-Population Dynamics  A Graphical Approach
    This book is an introduction into modeling population dynamics in ecology. Because there are several good textbooks on this subject, the book needs a novel ecological niche to justify its existence.

    Keywords: mathematical modelstabilitycompetitionSIRbifurcationconsumptionpopulation population dynamicsgeneral replicationnonlinear density dependenciesfunctional responsepersistencephase plan analysis

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    2012-Brian_Ingalls-Mathematical Modelling in Systems Biology An Introduction
    This is a comprehensive text with much biology background to motivate the mathematical modeling, exercises and answers, and many rich examples.

    Keywords: spatialsensitivity analysisgene regulatory networksstochasticbifurcationmetabolic networkselectrophysiologytransductionrate lawsbiochemical reactions

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    2012-Vivek_Patel-Chemical Kinetics
    The book is designed to help the reader, particularly students, researchers, research scholars, scientists, chemists and industry fraternity of chemistry and allied fields; understand the mechanics...

    Keywords: kineticschemistryreaction

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    1999-Khorasheh-Ahmadi-Gerayeli-Application of Direct Search Optimization for Pharmacokinetic Parameter Estimation
    For simple pharmacokinetic compartmental models, analytical solution to the governing differential equations provide a mean to evaluate the associated rate constants. Such methods, however, can not...

    Keywords: sum of square errorsleast squarespharmacokineticslineteicscompartmental modelsdirect search

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    A Simple Method for Predicting a Molecule's Biological Properties From Its Polarity
    The distinction between very polar and less polar substances is a foundation of biochemistry, cell biology, and physiology; it surfaces in multiple concept inventories and elaborations of...

    Keywords: Diffusionsolubilitycovalent bondshydrophilichydrophobicpartition coefficientplasma membranepolarity

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    2006-Juska-Gedminiene-Ivanec-Growth of Microbial Populations-Mathematical Modeling-Laboratory Exercises-Model-Based Data Analysis
    The aim is to teach the students to use a fresh approach to the problems they are familiar with, to come up with an articulate verbal model after a mental effort, to express it in rigorous...

    Keywords: population growth ratelogistic equationVerhulst equationgeneration timelag time

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    1999-PS_Crooke-S_Hota_JJ_Martini-JR_Hochkiss-A Mathematical Model for Carbon Dioxide Exchange
    A mathematical model is presented to study the effect of Tracheal Gas Insufflation (TGI) on the alveolar ventilation during passive, mechanical ventilation.

    Keywords: mechanical ventilationventilationcarbon dioxide exchangetracheal gas insufflationalveolar ventilationshunttwo-compartment model

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