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    Active Learning: Developing Self-Directed Learners Through Strong Intellectual Engagement
    When they were students, many current science instructors learned through traditional lectures. This mode of passive knowledge transmission has been shown to be less effective for student learning...

    Keywords: active learningmetacognitionconstructivism

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    Building Trees: Introducing evolutionary concepts by exploring Crassulaceae phylogeny and biogeography
    Teaching evolutionary theory is foundational for all biological sciences and a key aspect of overall science literacy. The conceptual framework for understanding evolution relies on thinking...

    Keywords: EvolutionphylogeneticsTree thinkingbiogeography

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    A new approach to course-based research using a hermit crab-hydrozoan symbiosis
    There are few feasible models for marine-focused inquiry laboratory activities, a notable shortcoming for instructors seeking to engage their students in meaningful, course-based research...

    Keywords: behaviorparasitismSymbiosismutualismcommensalism

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    Inexpensive Cell Migration Inquiry Lab using Zebrafish
    Cell migration is an important and interesting topic that has the potential to engage students in cell biology by its intrinsically active nature. However, most ways to investigate cell migration...

    Keywords: CytoskeletonCell migrationmodel organisms

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    Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Genetics (analyzing mutant promoters)
    Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression.  This laboratory lesson allows students...

    Keywords: bacteriasynthetic biologygene regulationtranscriptionstudent researchcentral dogmacloningpromoterreporter gene/protein

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    Authentic Ecological Inquiries Using BearCam Archives
    Learning through authentic scientific inquiries is essential for understanding the nature and process of science and for developing critical thinking and communication skills. It is logistically...

    Keywords: behaviorinterspecific interactionsPeer reviewauthentic inquiryintra-specific interactions

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    Does it pose a threat? Investigating the impact of Bt corn on monarch butterflies
    Aspiring scientists know that a hallmark of science is that experiments are repeatable and testable.  However, students do not often get opportunities to explore the replicability of...

    Keywords: ecologyCommunity EcologyBt cornGenetic modificationMonarch butterflies

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    Coevolution or not? Crossbills, squirrels and pinecones
    This case reinforces the concept of coevolution as a reciprocal change in genetic structure between or among two or more populations, by having students analyze and interpret data, build a...

    Keywords: fitnessCoevolutionCo-adaptation

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    Go Extinct! An Award-Winning Evolution Game That Teaches Tree-Thinking as Students Pursue the Winning Strategy
    Evolutionary trees communicate both the diversity and unity of life, a central and important scientific concept, as highlighted by the Vision and Change undergraduate biology education movement....

    Keywords: phylogeneticsnatural historyBiodiversitycladogramCommon ancestorEvolutionary treeLand vertebratesMonophyletic cladeTetrapods

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    SEAS CURE: Exploring Coral Biology Across Scales
    Complex biological concepts (like symbiosis and coral biology) that span multiple scales and cross disciplinary boundaries are often difficult for students to understand. This complexity is...

    Keywords: microscopyAnatomySymbiosisMetabolismbleachinginvertebratedinoflagellate

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    Design Your Own Flow Cytometry Experiment: A Four-Week Inquiry Laboratory
    Due to its importance to the field, flow cytometry should be one of the hallmark methods a student learns in the lab portion of an undergraduate immunology course. Flow cytometry is a classic lab...

    Keywords: Immunologyexperimental designFlow cytometryMice

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    A CURE for Salmonella: A Laboratory Course in Pathogen Microbiology and Genomics
    Rapid advances in genomics and bioinformatics, the vast amount of data generated by next-generation sequencing, and the penetration of the ‘-omics’ into many areas of biology have created a need...

    Keywords: epidemiologyresearchbioinformaticsgenomicspublic healthAntibiotic Resistant BacteriaSalmonellaDNA sequencingpathogenic bacteria

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    Sorry to Eat and Run: A Lesson Plan for Testing Trade-off in Squirrel Behavior Using Giving Up Densities (GUDs)
    All animals need to find and compete for food, shelter, and mates in order to survive and reproduce. They also need to avoid being eaten by predators. Optimal foraging theory provides a framework...

    Keywords: ecologyanimal behaviorAnimal form and functionAnimal nutritionSquirrel-Net

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    Doctor in the House: Improving Undergraduate Critical Thinking Skills Through Diagnosing Medical Case Studies
    Students in undergraduate anatomy and physiology courses are not often exposed to clinical examples of homeostatic imbalances, particularly ones that provide an opportunity to diagnose a...

    Keywords: medicinediagnosiscardiovasculardeductive reasoningdigestiveEndocrinehomeostatic imbalancehypothetico-deductive modelurinary

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    A CRISPR/Cas Guide RNA Design In Silico Activity
    CRISPR biotechnologies inspired by the Clustered Regularly Interspaced Short Palindromic Repeat RNA-guided nuclease adaptive bacterial immune system have revolutionized biology research and become...

    Keywords: bioinformaticsgene expressiongenetic basis of diseaseCRISPR/Cas9genetic engineeringin silico

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    Using Zebrafish in a Developmental Biology Lab Course to Explore Interactions Between Development and the Environment
    Important learning outcomes for biology students include the ability to develop experiments as well as pull together concepts across their coursework. The field of developmental biology, especially...

    Keywords: toxicologymorphogenesisorganogenesis

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    CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate students
    Providing undergraduate life-science students with a course-based research experience that utilizes cutting-edge technology, is tractable for students, and is manageable as an instructor is a...

    Keywords: bioinformaticsPCRphenotypingCRISPR/Cas9gene editingcloningGenotypingRestriction enzyme

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    Investigating Cell Signaling with Gene Expression Datasets
    Modern molecular biology is a data- and computationally-intensive field with few instructional resources for introducing undergraduate students to the requisite skills and techniques for analyzing...

    Keywords: genomicstranscriptionsignaling

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    The Leaky Neuron: Understanding synaptic integration using an analogy involving leaky cups
    Students have difficulty understanding synaptic integration in neural circuits, and how spatial and temporal summation combine in a target neuron to reach threshold.  This Lesson uses small...

    Keywords: neuron physiologyspatial summationsynaptic integrationtemporal summationthreshold

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    Using Place-Based Economically Relevant Organisms to Improve Student Understanding of the Roles of Carbon Dioxide, Sunlight, and Nutrients in Photosynthetic Organisms
    Biology students require broad preparation for diverse careers including agriculture, natural resource management, and laboratory research. Concurrent with this need, employers are seeking...

    Keywords: energyphotosynthesisbiomass

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