QUBES will have scheduled maintenance work beginning on Wednesday, June 26, 2024, 4pm ET/1pm PT. The platform will operate normally for most of the day, except for an extended outage period lasting no more than 4 hours. All running tool sessions will expire during the maintenance window. Please plan accordingly and we do apologize for any inconvenience. close

You are here: Home / Resources / Browse Resources

Open. Adaptable. Free.

Resources created by our members and partners.

The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

Text Search:
Applied Filters
    HITS: A network to promote high-throughput (HT) approaches through inquiry-based case studies
    Poster on the HITS project presented at the 2018 Annual Fall Conference for the National Center for Case Study Teaching In Science.

    Keywords: case studiesbig dataHITSHigh-throughput Discovery Science & Inquiry-based Case Studies for Today’s StudentsAnnual Fall Conference for the National Center for Case Study Teaching In ScienceBuffalo case studyHigh-throughput (HT) approaches

    1547

    views

    240

    downloads

    0

    comments

    0

    adaptations

    HITS: A network to create inquiry-based case studies that make high-throughput approaches and discovery accessible
    HITS brings together interdisciplinary groups of HT researchers and instructors to produce authentic HT case studies that can be implemented in a variety of courses, allowing students to analyze...

    Keywords: case studieshigh-throughputHITS

    3046

    views

    619

    downloads

    0

    comments

    0

    adaptations

    HITS: A network to create inquiry-based case studies that make high-throughput approaches and discovery accessible
    Poster on the work of the NSF-funded High-throughput Discovery Science & Inquiry-based Case Studies for Today’s Students (HITS) Research Coordination Network. Presented at the 2021 BIOME Institute.

    Keywords: case studieshigh-throughputHITSHigh-throughput Discovery Science & Inquiry-based Case Studies for Today’s Students2021 BIOME

    888

    views

    257

    downloads

    0

    comments

    0

    adaptations

    GEA Introductory lesson on RNA-Seq
    This RNA-Seq lesson uses the CyVerse VICE Platform and Jupyter notebooks to examine the expression of the leptin gene in samples from a mouse experimental design evaluating diet (high-fat vs....

    Keywords: data sciencebioinformaticsGenome BrowserRNAseqhigh throughput sequencingmRNAAlignmentNCBI Sequence Read Archive

    1450

    views

    677

    downloads

    0

    comments

    0

    adaptations

    The Human Microbiome Biodiversity in Health and Disease
    The students will analyze the human gut and vaginal microbiomes in healthy and diseased states using diversity of bacteria as determined by 16SrRNA sequence.
    1023

    views

    682

    downloads

    0

    comments

    0

    adaptations

    Tackling "Big Data" with Biology Undergrads: A Simple RNA-seq Data Analysis Tutorial Using Galaxy
    Analyzing high-throughput DNA sequence data is a fundamental skill in modern biology. However, real and perceived barriers such as massive file sizes, substantial computational requirements, and...

    Keywords: bioinformaticsDNA sequenceRNAseqgene expression

    4637

    views

    866

    downloads

    0

    comments

    0

    adaptations

    Sequence Similarity: A Quick Introduction to Bioconductor
    Following the Sequence Similarity exercises by Kleinschmit, et al., this tutorial will guide students in using the Bioconductor suite of R packages to likewise compute sequence similarity.

    Keywords: bioinformaticssequencingNIBLSEmultiple sequence alignmentsequence similarityBLOSUM scoring matrixBioconductor

    956

    views

    961

    downloads

    0

    comments

    0

    adaptations

    Biogeography of plant-associated fungi: who lives where and why?
    This dataset of fungal communities associated with the leaves an endemic Hawaiian tree provides students opportunities to explore relationships between environmental variables and microbial...

    Keywords: small group activityinquiry-based learningbiogeographymicrobial ecology

    2010

    views

    1465

    downloads

    0

    comments

    0

    adaptations

    HITS: A Network to Create Inquiry-based Case Studies | BIOME 2022
    We created the NSF-funded High-throughput Discovery Science & Inquiry-based Case Studies for Today’s Students (HITS) Research Coordination Network to address this gap. HITS brings together...

    Keywords: case studiesHigh-throughput Discovery Science & Inquiry-based Case Studies for Today’s StudentsHigh-throughput (HT) approaches

    483

    views

    88

    downloads

    0

    comments

    0

    adaptations

    Does Organelle Shape Matter? Exploring Cell Shape through the Allen Cell Explorer and High-content Microscopy Datasets
    The morphology and localization of structures inside the cell are often assumed to fit the ideal images found in biology textbooks. This interrupted case study using high-throughput microscopy data...
    2013

    views

    3074

    downloads

    0

    comments

    0

    adaptations

    Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson
    There is a growing need for integration of “Big Data” into undergraduate biology curricula. Transcriptomics is one venue to examine biology from an informatics perspective. RNA sequencing has...

    Keywords: bioinformaticscancertranscriptomicshigh-throughputData wranglingSingle cell RNA sequencingq

    6262

    views

    1576

    downloads

    0

    comments

    0

    adaptations

    Using Raw Sequence Data to Analyze Tumor Suppressor Mutations
    Learning to identify DNA sequence variants from raw sequencing data (electropherograms) is a basic molecular biology skill with applications to basic research and clinical practice. Yet learning to...

    Keywords: bioinformaticsmutationDNAgenomic visualizationparts of a geneclinical consequencesraw data

    200

    views

    15

    downloads

    0

    comments

    0

    adaptations

    Does Organelle Shape Matter?: Exploring Patterns in Cell Shape and Structure with High-Throughput (HT) Imaging
    Organelle structure has been studied and visualized for decades; however, publicly available databases that use improved high-throughput microscopy of gene-edited cell lines have recently...

    Keywords: modelingcase studymicroscopystructureOrganellesHigh-throughput (HT)Endoplasmic Reticulum (ER)Fluorescent microscopyHuman Cell Biology

    4508

    views

    442

    downloads

    0

    comments

    0

    adaptations

    Advances in Genome Sequencing with Nathan Olson
    In this Lunch with a Scientist episode, we discuss Genome Sequencing and Bioinformatics with National Institute of Standards and Technology (NIST) biologist Nate Olson, Ph.D.

    Keywords: Bioinformatics and Genomics

    453

    views

    99

    downloads

    0

    comments

    0

    adaptations

    Using QIIME to Interpret Environmental Microbial Communities in an Upper Level Metagenomics Course
    Metagenomics is rapidly evolving due to advances in sequencing technologies and bioinformatics, but without proper training to interpret these datasets, student understanding remains limited. Aimed...

    Keywords: microbiome

    1378

    views

    284

    downloads

    0

    comments

    0

    adaptations

    An Introduction to Eukaryotic Genome Analysis in Non-model Species for Undergraduates: A tutorial from the Genome Consortium for Active Teaching
    Advances in Next Generation Sequencing (NGS) technology have led to development of many research methods for analyzing genomic data. Students studying biology at the undergraduate level must hone...

    Keywords: Speciationgenome evolutiongenetic variation

    2477

    views

    406

    downloads

    0

    comments

    0

    adaptations

    CURESUB Lecture 5 - OMICS
    s assistant professor in the department of medicine at Rutgers Robert Wood Johnson Medical School, Manisha Bajpai, PhD., led the Gastroenterology division’s clinical and translational research...
    1867

    views

    108

    downloads

    0

    comments

    0

    adaptations

    A Fun Introductory Command Line Exercise: Next Generation Sequencing Quality Analysis with Emoji!
    This resource is a fun computer-based intro to command line programming. The activity takes FASTQ NGS data files and runs a fun program called FASTQE.

    Keywords: data sciencebioinformaticsnext generation sequencingquality controlFASTQgenomicsprogrammingNIBLSElinuxmicrobiomeIllumina sequencingcommand lineFASTQEFASTPNGS analysisterminalMacemojiPhred scoreTrimmingshort read

    2566

    views

    2286

    downloads

    1

    comments

    0

    adaptations

    A CURE for Salmonella: A Laboratory Course in Pathogen Microbiology and Genomics
    Rapid advances in genomics and bioinformatics, the vast amount of data generated by next-generation sequencing, and the penetration of the ‘-omics’ into many areas of biology have created a need...

    Keywords: epidemiologyresearchbioinformaticsgenomicspublic healthAntibiotic Resistant BacteriaSalmonellaDNA sequencingpathogenic bacteria

    5686

    views

    1120

    downloads

    0

    comments

    0

    adaptations

    Analysis of Microbiomes Using Free Web-Based Tools in Online and In-Person Undergraduate Science Courses
    Our understanding of microbiomes, or the collection of microorganisms and their genes in a given environment, has been revolutionized by technological and computational advances. However, many...

    Keywords: microbiomeDNA SubwayCyVerseCourse based undergraduate researchQIIME2ranacapa

    4017

    views

    262

    downloads

    0

    comments

    0

    adaptations

    Close

    Home

    Search