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    Sickle Cell Disease and Natural Selection in Humans
    A short film explores the evolutionary connection between an infectious disease, malaria, and a genetic condition, sickle cell anemia. The animation explores the genetic causes and biological...

    Keywords: HHMI BioInteractive

    1964

    views

    420

    downloads

    0

    comments

    1

    adaptations

    Cystic Fibrosis Mechanism and Treatment
    This animation shows how mutations in an ion channel protein lead to the genetic disease cystic fibrosis. The animation also discusses how research on this protein has been used to develop...

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymacromoleculesGenetic diseaseCell Structure & Function

    1115

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    200

    downloads

    0

    comments

    0

    adaptations

    Quantifying Bacterial Growth in the Guts and Hemolymph of Fruit Flies: Mathematical Modeling and Data Interpolation/Extrapolation
    In this activity, students will analyze raw data obtained from an experiment that explores the effect of overexpressing the Ssk protein in order to strengthen the intestinal barrier and prevent...

    Keywords: graphingexponential growthlinear modelsqbccinterpolationConcepts in Statistics and Precalculus Understanding exponential rates and linear slopesExtrapolation

    2021

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    320

    downloads

    0

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    0

    adaptations

    Geoscience Methods and Resources for K-5 Pre-Education Majors
    : Exploring Geoscience Methods was an excellent capstone experience for Elementary Education Majors. The class I used this module with was 24 students of various backgrounds and academic...

    Keywords: geneticsvideosQUBESecologyResources @ HHMI - BioInteractiveMathematical Biologycalculusjavaorganismal biologyquantitative biologybioinformaticsneurosciencegenomicscancerSecondaryyoutubemicrobiomeFaculty Mentoring NetworksalamanderCapture mark-recaptureAudience level - Introductory UG - majorsAudience level - Introductory UG - non-majorsecosystemsgenetic basis of diseasebiology of cellshuman reproductionfood chainIntroduction to Modelingrandom number generatorPost-secondaryLower DivisionPossible TasksModeling ProjectBuildCompareEvaluateexponential decayrecursionabsorptionelimination

    1634

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    2174

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    0

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    0

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    6-045-CholeraTranmission-ModelingScenario
    During the project described here, the students will learn how to solve and address a practical problem such as cholera transmission using various mathematical tools.

    Keywords: infectious diseasecholeraendemicdisease-freetransmission ratewaterborne pathogen

    189

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    83

    downloads

    0

    comments

    0

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    Sickle Cell Disease Case Study
    A short film explores the evolutionary connection between an infectious disease, malaria, and a genetic condition, sickle cell anemia. The animation explores the genetic causes and biological...

    Keywords: HHMI BioInteractive

    2039

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    1650

    downloads

    0

    comments

    0

    adaptations

    Social Distancing Simulation in NetLogo
    A NetLogo simulation that shows the effects of social distancing on the spread of infectious disease.
    913

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    410

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    0

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    0

    adaptations

    You and Your Oral Microflora: Introducing non-biology majors to their “forgotten organ”
    With limited time available for laboratory activities, introductory science courses for non-science majors typically use the laboratory period to reinforce material that was previously presented...

    Keywords: bacteriamicrobiomeBLASTmicrobesDNA replicationPolymerase chain reaction (PCR)

    2216

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    274

    downloads

    0

    comments

    0

    adaptations

    Human Population Growth and Greenhouse Gas Emissions
    Humans alter the climate by emitting greenhouse gases, by changing planetary albedo, and by altering atmospheric chemistry. Between 1900 and 2000, humans' emissions of carbon into the atmosphere...

    Keywords: demographyhuman populationgreenhouse gas emissions

    289

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    366

    downloads

    0

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    0

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    1964-Aghajanian-Bing-Persistence Of LSD In Plasma In Human Subjects
    Two micrograms per kilogram of LSD-25 was administered intravenously to five normal human subjects. The concentration of[ drug in plasma was determined serially over the subsequent 8 hours. We...

    Keywords: LSDscoreplasmalysergic acid diethylamidehuman subjuects

    146

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    60

    downloads

    0

    comments

    0

    adaptations

    Maternal transmission of microbiome
    Understanding the cascading effects of the transfer of maternal microbiome during a vaginal birth (vs. a c-section) to the well-being of a newborn.

    Keywords: microbiomehuman reproduction

    1832

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    506

    downloads

    0

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    0

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    The impact of diet and antibiotics on the gut microbiome
    The goal of this article is to describe an active learning exercise that can be used in a variety of advanced microbiology courses, including bacterial physiology, ecology, or systems biology. The...

    Keywords: microbiomeenvironmental controlhost responsemetabolites

    1995

    views

    226

    downloads

    0

    comments

    0

    adaptations

    Using Raw Sequence Data to Analyze Tumor Suppressor Mutations
    Learning to identify DNA sequence variants from raw sequencing data (electropherograms) is a basic molecular biology skill with applications to basic research and clinical practice. Yet learning to...

    Keywords: bioinformaticsmutationDNAgenomic visualizationparts of a geneclinical consequencesraw data

    327

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    31

    downloads

    0

    comments

    0

    adaptations

    1-089-SpreadOfDisease-ModelingScenario
    In this project I want to use the algebra based concept “difference quotient” to solve differential equations models with the help of Excel. That means even students with only a College Algebra...

    Keywords: SIR modelProportionderivativedifference quotientSleeping Beautycontagious disease

    235

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    121

    downloads

    0

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    0

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    2012-Tweedle-Smith-Mathematical model of Bieber Fever-The most infectious disease of our time
    We develop a mathematical model to describe the spread of Bieber Fever, whereby individuals can be susceptible, Bieber-infected or bored of Bieber.

    Keywords: infectious diseasediseaseinfectionmediaJustin BieberBieber feversymptomsboredreproductive ratio

    124

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    41

    downloads

    0

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    0

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    2011-Nakul-Chitnis-Introduction to Mathematical Epidemiology - Deterministic Compartmental Model
    Deterministic compartmental models form the simplest models in the mathematical study of infectious disease dynamics. They assume that a population is homogenous (all people are the same) and the...

    Keywords: sensitivitydiseaseinfectionthresholdcompartmentbifrucation

    142

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    61

    downloads

    0

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    0

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    2011-Gaff-Lenhart-Use of optimal control models to predict treatment time for managing tick-borne disease
    Tick-borne diseases have been on the rise recently, and correspondingly, there is an increased interest in implementing control measures to decrease the risk. Optimal control provides an ideal tool...

    Keywords: diseaseoptimal controlTICKtick modeehrlichiosisbang bang control

    122

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    45

    downloads

    0

    comments

    0

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    Nicholas' Story
    This 3 part case on sickle cell disease focuses on visualizing and understanding the molecular basis of its cause, symptoms, complications, management, treatment, and possible cures.

    Keywords: Hemoglobinmolecular visualization and analysissickle cell diseasePDBMolecular Case Study

    1176

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    488

    downloads

    0

    comments

    0

    adaptations

    Nicholas' Story
    This 3 part case on sickle cell disease focuses on visualizing and understanding the molecular basis of its cause, symptoms, complications, management, treatment, and possible cures.

    Keywords: Hemoglobinmolecular visualization and analysissickle cell diseasePDBMolecular Case Study

    1621

    views

    510

    downloads

    0

    comments

    4

    adaptations

    The Impact of Diet and Antibiotics on the Gut Microbiome: Distance Education Variant
    The goal of this article is to describe a variation of an active learning exercise that was previously published by the same author under a similar title. The variation describes modifications...

    Keywords: microbiomenutritionbacterial metabolitesgut bacteriahost response

    1391

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    173

    downloads

    0

    comments

    0

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