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    Exploration of the Human Genome by Investigation of Personalized SNPs
    To increase students' interest in their own genomes, this computer-based laboratory lesson is designed to be coupled with the opportunity for the students to be genotyped by the consumer sequencing...

    Keywords: bioinformaticsNIBLSECourseSourcegenomic wide association studiesUCSC genome browsersingle nucleotide polymorphism

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    Introduction to Mathematical Modeling in Biotechnology, Cell Biology, and Physiology
    The course is a mathematical and computational exploration of five diverse areas of biology: human locomotion, gene sequence analysis, signal transduction pathways involved in cancer,...

    Keywords: mathematical modelingcoursehuman locomotionneuroanatomyneurophysiologysignal transductiongene sequence analysis

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    Environmental Justice and Freshwater Resources
    This module enables students to identify the freshwater components of the hydrologic cycle and connect them to the basic need of all human beings for equal access to clean freshwater.

    Keywords: sustainabilityenvironmental scienceglobal changeexamwater resourcesenvironmental sociologyResources @ InTeGrate

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    Bacteria to Brains in Backyard Coyotes: An Interdisciplinary Pedagogical Case Study
    Our interdisciplinary pedagogical case study explores the differences between rural and urban coyotes at the levels of organismal and community ecology. The focus is on how coyotes’ gut...

    Keywords: dietanimal behaviorimmune systemmicrobiomeNervous systemgut-brain axisImmunoReachdysbiosisCoyoteCytokines

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    "Reading groups" in an undergraduate biology course: A peer-based model to help students develop skills to evaluate primary literature
    Undergraduates who learn to evaluate primary literature demonstrate an enhanced ability to understand the process of science, weigh scientific evidence, and think critically (e.g. 6,8). Studies...

    Keywords: primary literaturecritical thinkingSelf-EfficacyDiscussionPeer-based Learning

    1920

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    1984-Marguerite_Hays-Compartmental Models for Human Iodine Metabolism
    Compartmental models for the various aspects of human iodine metabolism are reviewed, emphasizing the role of Mones Berman in the development of this field.

    Keywords: compartment modeliodinethyroid

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    Rivers as Social-Ecological-Technological Systems: Integrative Issue Formulation and Problem Solving
    Flowing surface waters continue to capture the human imagination and are increasingly harnessed by many interdependent human activities. Existing theories for studying rivers as cohesive ecological...

    Keywords: Interdisciplinary STEMProblem based learningcomplex systemsexperiential learningRiver Field Studies Network

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    COVID-19: Molecular Basis of Infection-ADAPTATION
    This case was written in Spring 2020 during the COVID-19 pandemic. It focuses on understanding the structure and interaction of the SARS-Cov-2 viral spike protein that facilitates infection in...

    Keywords: infectionvaccinemolecular visualization and analysisCOVID19PDBSARS-CoVMolecular Case Study

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    Antibiotic Resistance Genes Detection in Environmental Samples
    Our aim is to provide an authentic research experience for undergraduate students in a variety of biology courses through collaboration between a four-year university and a community college. This...

    Keywords: geneticsenvironmentmicrobiologyUndergraduateantibiotic-resistancePCRgel electrophoresisauthentic inquiry

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    Evolution of Tusklessness in African Elephants
    The exploitation of African elephants in the form of ivory poaching is exacerbated by warfare. The affects of this anthropogenic evolutionary force on the African savanna elephant (Loxodonta...

    Keywords: Hardy-Weinbergchi-squaredEvolutionExponentsRatiospercentselephantsGorongosa National ParkAfricaqbccUnderstanding fractionsSolving Equations and InequalitiesConcepts in Statisticsusing statisticstusk & tusklessIvory poachingFractions and Mixed NumbersDecimals

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    Joel E. Greengiant Learns About Peas: From Nucleotides to Selection
    This case study follows purveyors of peas, Joel E. and Jolene Greengiant, as they learn about the origin, biochemistry, genetics and eventual artificial selection of sweet (wrinkled) peas, all in...

    Keywords: geneticspopulation geneticsEvolutionintroductory biologycase studybiologyResources @ NSF - NCCSTSmeiosisMendel’s peaspea plantPisum sativumMendel’s Lawsmolecular geneticsmutationnucleotide insertionartificial selectionstarch synthesisstarch branching enzymeplant domesticationlegumesResources @ QUBES - Teaching & Reference

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    Using computational molecular modeling software to demonstrate how DNA mutations cause phenotypes
    Students require a deep understanding of the central dogma before they can understand complex topics such as evolution and biochemical disorders. However, getting undergraduate biology students to...

    Keywords: Protein Structurecomputational modelingcentral dogmaplant leaf structurePhenotype/Genotype

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    Debating Conservation: Developing Critical Thinking Skills in Introductory Biology Classes
    Role-playing activities in the classroom promote students’ critical thinking, research, and communication skills. We present an activity where students debate a current controversy in...

    Keywords: Restorationtrophic cascadeecosystem function

    1991

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    Maria vs Malaria - AR Adaptation
    This case study focuses on a specific enzyme Lactate Dehydrogenase (LDH) in the malarial parasite as a target for treating malaria. Students will be able to view selected molecular views from the...

    Keywords: bioinformaticsAugmented RealityLarge class sizemolecular visualizationstructure-functionuniprotProtein Data BankMolecular Case StudyMolecular CaseNet

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    2014-Hrydziuszko-EtAl-Mathematical Two-compartment Model of Human Cholesterol Transport
    We develop a two-compartment mathematical model to investigate cholesterol transport in the circulatory system and its de novo synthesis in the liver.

    Keywords: metabolic syndromecompartmentcholesteroltwo-compartment modelcholesterol transport

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    2010-Shianga-EtAl-Computational model of the human glucose-insulin regulatory system
    A computational model of insulin secretion and glucose metabolism for assisting the diagnosis of diabetes mellitus in clinical research is introduced. The

    Keywords: glucose tolerance testsum of squared residualsmultiple shooting methodcost function

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    Integrating the modeling of biogeochemical cycles and energy flow
    This in-class activity challenges students to create and then integrate models of how carbon, nitrogen, water and energy all move within an ecosystem. Using 15 provided standard pools, they work...

    Keywords: modelingecologyintegration4DEE FrameworkBiogeochemical cycles

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    javaFOODWEB
    More than 100 food web matrices (multiple predators/prey Excel worksheets) are included with the javaFOODWEB tool.

    Keywords: niche spacesCommunity Ecologyfood webspredator-prey interactionsMatricestrophic chain

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    Evolution Through Natural Selection
    This Excel workbook simulates the population genetics of a single gene with two alleles, allowing the user to set the initial allele frequencies and enter parameters for a variety of different...

    Keywords: population geneticsNatural Selection

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    ESS: Evolutionary Stable Strategies Game Theory Module
    This Excel workbook illustrates a number of ESS examples. Each example allows the user to manipulate the initial population for each strategy and the fitness payoffs and costs for each strategy.

    Keywords: population geneticsfitnessgame theorySequence alignmentevolutionary stable strategies

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