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    2020-TeachingModule-SpreadOfCommonColdSimulation
    This simulation is meant to introduce the idea of a differential equation model and investigate the impact of heightened hygiene and decreased interactions on the spread of an infectious disease....

    Keywords: simulationmoduleinfectious diseasediseasespreadTeaching Modulespread of disease

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    2017-Allali-EtAl-Mathematical Modeling of the Adaptive Immune Responses in the Early Stage of the HBV Infection
    The aim of this paper is to study the early stage of HBV infection and impact delay in the infection process on the adaptive immune response, which includes cytotoxic T-lymphocytes and antibodies.

    Keywords: logisticHBV infectionadaptive immunie responseT-lymphocytes

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    2016-Helena_Sofia_Rodrigues-Application of SIR epidemiological model new trends
    In this paper, the basic transmission model is analyzed, as well as simple tools that allows us to extract a great deal of information about possible solutions. A set of applications - traditional...

    Keywords: epidemiologybasic reproduction numberSIR

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    2010-Del-Ciello-EtAl-Modeling Disease
    We model the transmission of a disease through a population. Such modeling is very important to the study of epidemiology and the practice of medicine.

    Keywords: diseasespreadcarriessymptomaticasymptomatic

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    2020-Ciaroshi-How_COVID-19_Spreads_MathModels
    On December 31, 2019, the Chinese city of Wuhan reported an outbreak of a novel coronavirus (COVID-19) that has since killed over 4,200 people. As of March 11, 2020, over 118,000 infections—have...

    Keywords: diseasecovidoutbreakWuhancoronoavirus

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    SIR BuildIt
    An introduction to epidemiological models using interactive Excel worksheets

    Keywords: epidemiologymodelingTeaching Material @ BioQUEST_ESTEEMExcelinfectious diseaseInfectious Disease ModelingSIR modelsSIR

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    2009-Munz-EtAl-When Zombies Attack-Mathematical modelling of an Outbreak of Zombie Infection
    We introduce a basic model for zombie infection, determine equilibria and their stability, and illustrate the outcome with numerical solutions.

    Keywords: zombiesinfectionepidemicwater treatmentlatent infectionquarantineimpulsive eradication

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    2020-Chen_Et_Al-MathModel_Simulation_Phase-Based_Transmissability_Corona_Virus
    In this study, we developed a Bats-Hosts-Reservoir-People transmission network model for simulating the potential transmission from the infection source (probably be bats) to the human infection.

    Keywords: basic reproduction numbercoronavirusnext generation matrixtransmissibilitynovel coronavirus

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    6-003-SchoolFluEpidemic-ModelingScenario
    We offer a model of the spread of flu in a school dormitory and are asked to find when the flu levels reach their peak and explain long term behavior of the spread of the flu.

    Keywords: infectionepidemicSIR modelflupeakschool children

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    Targeting Misconceptions in the Central Dogma by Examining Viral Infection
    Understanding the central dogma and how changes in gene expression can impact cell function requires integration of several topics in molecular biology. Students often do not make the necessary...

    Keywords: datatranscriptionvirustranslationprotein functionmembrane transportPredictions

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    2010-Jungck-EtAl-Mathematical Manipulative Models-In Defense of Beanbag Biology
    This paper offers up samples of projects from the Bio- QUEST Curriculum Consortium’s 24-yr experience of holding faculty development workshops for biology and mathematics educators.

    Keywords: epidemiologysimulationinfectious diseasedisease transmissiondiseasein-class activitybean bag activity

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    Sequence Similarity Resource Adaptation: Exploring Ebola Virus
    This adaptation of the sequence similarity resource provides biology students with a basic set of bioinformatics concepts and tools. These concepts and tools are used to explore relationships...

    Keywords: phylogeneticsbioinformaticsEbolasequencingFASTANCBINIBLSEalgorithmsincubatorsBLASTmultiple sequence alignmentsequence similarityBLOSUM scoring matrixneighbor-joining distance matrixCourseSourcephylogram

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    2008-Huangi-Lu-Modeling long-term longitudinal HIV dynamics with applications to an AIDS clinical study 
    To better understand the factors responsible for the virological failure, this paper develops the mechanism-based nonlinear differential equation models for characterizing long-term viral dynamics...

    Keywords: longitudinal dataAIDSantiretroviral drug therapyBayesian nonlinear mixed-effectstime-varying drug efficacyHIV dynamics

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    Tackling "Big Data" with Biology Undergrads: A Simple RNA-seq Data Analysis Tutorial Using Galaxy
    Analyzing high-throughput DNA sequence data is a fundamental skill in modern biology. However, real and perceived barriers such as massive file sizes, substantial computational requirements, and...

    Keywords: bioinformaticsDNA sequenceRNAseqgene expression

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    When tests disagree, how do I know if I have COVID-19?
    Students will learn about infectious disease and the immune response to infection by investigating different types of tests (PCR, antigen, and antibody tests) to detect the SARS-CoV-2 viral genetic...

    Keywords: geneticsVision and Changeintroductory biologyinfectious diseasemolecular biologycore competenciesRT-PCRviruscore conceptsnon-majors biologySARS-CoV-2antibodyAntigenImmunoReachmolecular DiagnosticsCOVID-19 transmission

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    Forensic Phylogenetics: Implementing Tree-thinking in a Court of Law
    Here we describe an in-class activity developed for Evolutionary Biology and Biodiversity (BioEE1780) at Cornell University, an introductory course required of all biology majors. This activity...

    Keywords: phylogeneticsTree thinkingparaphyly

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    Infectious Chocolate Joy with a Side of Poissonian Statistics: An activity connecting life science students with subtle physics concepts
    Introductory physics courses are required for many programs in the life sciences, yet traditional curricula fail to help students meaningfully connect physical concepts with biological...

    Keywords: quantitative biologyHIVmultiplicity of infectionPoisson DistributionPhysics for biologists

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    To Vaccinate or Not to Vaccinate
    To vaccinate or not to vaccinate, that is the question. Much of the recent trend in society against vaccination is that the general population does not understand 1) how vaccines work and 2) how...

    Keywords: pathogenELISAimmunityantibodyAntigen

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    Dynamic Daphnia: An inquiry-based research experience in ecology that teaches the scientific process to first-year biologists
    This authentic research experience lesson teaches the core concept of systems and the competencies of quantitative reasoning, communication, and the ability to apply science. The research is...

    Keywords: statisticsecologyscientific methodexperimental designAbiotic and Biotic FactorsDependent and Independent Variables

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    Understanding Host-Pathogen Interactions With the Use of Galleria mellonella
    The Galleria mellonella; the larvae of the Greater Wax Moth, is a safe and effective means to study host-pathogen interactions in the undergraduate setting. The use of animal models in the teaching...

    Keywords: innate immunitybacterial pathogenesisHost-pathogen interactionsGalleria mellonellaVirulence

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