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    Investigating Gene Expression and Cell Specialization in Axolotl Embryos
    The process of cell specialization is critical to the formation and function of tissues in animals and plants. Although gene expression, including the regulation of transcription, is taught in most...

    Keywords: developmenttranscriptiongene expressionmodel organismembryo

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    Sequence Similarity: An inquiry based and "under the hood" approach for incorporating molecular sequence alignment in introductory undergraduate biology courses
    Introductory bioinformatics exercises often walk students through the use of computational tools, but often provide little understanding of what a computational tool does "under the...

    Keywords: BLASTmultiple sequence alignmentsequence similarityphylogramZika virusAlgorithmScoring Matrix

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    Teaching Advanced Concepts in Regulation of the Lac Operon With Modeling and Simulation
    Success in biochemistry and other life science courses requires that students understand important biological concepts. One of these concepts is how gene regulation ensures that homeostasis is...

    Keywords: gene regulationinducible operonProkaryotic cellPhosphoenolpyruvate transferase system (PTS)

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    How to Find a Gene: Retrieving Information From Gene Databases
    A strong understanding of distinct gene components and the ability to retrieve relevant information from gene databases are necessary to answer a diverse set of biological questions. However, often...

    Keywords: NCBItranscriptiontranslationGene StructureGene databasesEnsembl

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    A Momentum-First Approach to Newton’s Second Law
    Students frequently struggle with seeing the connection between forces and motion in introductory physics. This lesson is part of a combined momentum and kinematics unit that first teaches...

    Keywords: group workMomentumNewton's Laws

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    Online Adaptation of the Cell Engineer/Detective Lesson
    One of the most fundamental themes of biology is the relationship between structure and function, which is particularly evident when it comes to cells; however, the traditional cartoon depictions...

    Keywords: cell functionCell StructureOrganelles

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    Helping Students to Metacognitively Read Scientific Literature With Talking to the Text
    Reading primary scientific literature enhances students’ understanding of material, increases their self-efficacy, and critical thinking skills. However, scientific articles often present...

    Keywords: scientific literaturereading comprehensionmetacognitionScience process skillsTalking to the TextDense Scientific Texts

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    Exploring the Complexities of Photosynthesis Through a Comic Strip
    Photosynthesis is a conceptually challenging topic. The small scale at which photosynthesis takes place makes it difficult for students to visualize what is occurring, and students are often...

    Keywords: photosynthesislight-dependent reactionsCalvin cyclechloroplast

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    Problem-Based Learning for Physiology: Synthesizing the Cardiovascular System, Respiration, Macronutrient Metabolism, and Renal Function
    Problem Based Learning (PBL) is a valuable tool for helping students overcome reliance on memorization by scaffolding opportunities for them to practice the competency of...

    Keywords: MetabolismObesityblood pressurecardiac functioncardiovascularmetabolic syndromerenalRespirationrespiratory system

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    Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Introductory Biology (identifying new promoters)
    Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression. This laboratory lesson allows students to...

    Keywords: bacteriasynthetic biologygene regulationtranscriptionstudent researchcentral dogmacloningpromoterreporter gene/protein

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    Using Constructed Response Questions on High-Stakes Assessments in Large Classes With Limited Support
    Large lecture courses often rely heavily, and sometimes exclusively, on Multiple Choice (MC) exams to assess student learning. Constructed Response (CR) questions, in which students generate their...

    Keywords: assessmenttestexamLarge classconstructed responseshort answerscoring

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    Using Raw Sequence Data to Analyze Tumor Suppressor Mutations
    Learning to identify DNA sequence variants from raw sequencing data (electropherograms) is a basic molecular biology skill with applications to basic research and clinical practice. Yet learning to...

    Keywords: bioinformaticsmutationDNAgenomic visualizationparts of a geneclinical consequencesraw data

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    How to Design a Classroom Activity that Integrates 3D Print Models with Active Learning
    Student exploration of relevant physical models can deepen knowledge of course material. In this guide we describe a method by which instructors can integrate 3D printing technology with an...

    Keywords: active learning3D print modelsclassroom jigsaw

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    BioMap Degree Plan: A project to guide students in exploring, defining, and building a plan to achieve career goals
    Traditional college students begin their academic journey with a variety of ideas about the careers they might ultimately pursue. Some students have always known what they want to do, some have...

    Keywords: Career ExplorationCo-curricularsDegree Planning

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    Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Genetics (analyzing mutant promoters)
    Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression.  This laboratory lesson allows students...

    Keywords: bacteriasynthetic biologygene regulationtranscriptionstudent researchcentral dogmacloningpromoterreporter gene/protein

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    Discovery and Invention: A Reflection on Representation in Science
    Despite increased awareness of the lack of equity and inclusion in the STEMM classroom, lessons on DEI topics are treated as separate to the scientific curriculum being taught. Rarely are...

    Keywords: EquityDiversity and Inclusionantiracism

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    Building Trees: Introducing evolutionary concepts by exploring Crassulaceae phylogeny and biogeography
    Teaching evolutionary theory is foundational for all biological sciences and a key aspect of overall science literacy. The conceptual framework for understanding evolution relies on thinking...

    Keywords: EvolutionphylogeneticsTree thinkingbiogeography

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    Application of a Bacterial Experimental Evolution System to Visualize and Teach Evolution in Action: A Course-Based Undergraduate Research Experience
    Concepts of evolution are typically taught through examples of extremely long timescales, which do not always resonate broadly. Here, we describe a course-based undergraduate research experience...

    Keywords: EvolutionmutationcompetitionNatural Selectionregulationstructure and functionreproductive fitnessgenotype to phenotypehomologs

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    My Fish Tank: An Active Learning Activity for Bacterial Nitrogen Metabolism
    This active learning activity introduces students to the second part of the nitrogen cycle, nitrification. In terrestrial and aquatic environments, bacteria from the Nitrosomonas and Nitrobacter...

    Keywords: nitrogen cyclenitrificationnitrifying bacteria

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    Does Organelle Shape Matter?: Exploring Patterns in Cell Shape and Structure with High-Throughput (HT) Imaging
    Organelle structure has been studied and visualized for decades; however, publicly available databases that use improved high-throughput microscopy of gene-edited cell lines have recently...

    Keywords: modelingcase studymicroscopystructureOrganellesHigh-throughput (HT)Endoplasmic Reticulum (ER)Fluorescent microscopyHuman Cell Biology

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