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    Integrating Primary Literature in a Lecture Course Using a Modified Version of the C.R.E.A.T.E. Approach
    Reforms in undergraduate science education place an increasing emphasis on teaching the skills of practicing scientists, such as reading and interpreting the primary research literature. Many...

    Keywords: primary literatureDiscussionModified JigsawPeer-based Learning

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    The Pipeline CURE: An Iterative Approach to Introduce All Students to Research Throughout a Biology Curriculum
    Participation in research provides personal and professional benefits for undergraduates. However, some students face institutional barriers that prevent their entry into research, particularly...

    Keywords: epigeneticsundergraduate researchmendelian inheritanceSelf-EfficacyCUREsnature of scienceResiliencecurriculum strategiesreprogramming

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    Understanding Protein Domains: A Modular Approach
    An understanding of protein structure, function, and interaction is central to biochemistry. One angle into this topic is to engage students in considering protein domains as modules that develop...

    Keywords: Protein Structure

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    Serotonin in the Pocket: Non-covalent interactions and neurotransmitter binding
    This lesson introduces beginning biochemistry students to the concept of a biomolecule binding site, such as a neurotransmitter receptor site or an enzyme active site. A simple organic molecule,...

    Keywords: active sitebindingbinding sitehydrogen bondinghydrophobic effectionic interactionsnon-covalent forces

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    Grow the Gradient: An interactive countercurrent multiplier game
    The countercurrent multiplier of the loop of Henle in a mammalian kidney is a challenging concept for instructors to teach and for students to learn. We developed an interactive game to support...

    Keywords: countercurrent multiplierexcretory systemkidneyloop of Henlemembrane transport

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    Cell Signaling Pathways - a Case Study Approach
    Signaling and gene expression are fundamental to cell biology and developmental biology. Although these topics are highly interrelated, they typically appear in separate units in a course. We use a...

    Keywords: signal transductiongene expressionCell communicationgenetic disordersregulation of enzyme activity

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    An Open Source, Collaborative Electronic Notebook for Undergraduate Laboratory Classes
    To overcome many of the limitations of the paper laboratory notebook (PLN), we developed an electronic laboratory notebook (e-LN) for the Dynamic Genome course at the University of California. The...

    Keywords: data collectionData annotationNotebook Skills

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    Using Undergraduate Molecular Biology Labs to Discover Targets of miRNAs in Humans
    Incorporating authentic research experiences into undergraduate labs, while shown to be particularly effective at engaging and retaining students in STEM majors, can be difficult to accomplish...

    Keywords: gene regulationmicroRNAsgene expression

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    Using Pathway Maps to Link Concepts, Peer Review, Primary Literature Searches and Data Assessment in Large Enrollment Classes: An example from teaching ecosystem ecology
    As with many other complex topics, teaching ecosystem ecology can be particularly difficult in terms of helping students understand the relationships between the various component parts. We...

    Keywords: energyecosystemNutrientsPathway

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    Homologous chromosomes? Exploring human sex chromosomes, sex determination and sex reversal using bioinformatics approaches
    Constructing a robust understanding of homologous chromosomes, sex chromosomes, and the particulate nature of genes is a notoriously difficult task for undergraduate biology students. In this...

    Keywords: bioinformaticsautosomehomologous chromosomeshomologous recombinationsex chromosomesex determinationsex reversal mutations

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    Hands-On, Hands-Off: The Community College Genomics (ComGen) Course-Based Undergraduate Research Experience
    Science is a process of discovery where failure is inherent and iteration is necessary, yet instructors often teach the scientific process as if it is a controlled, highly supervised, confirmatory...

    Keywords: geneticssequencingDNAbacterium

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    Breaking It Down: What Factors Control Microbial Decomposition Rates?
    Demonstrating and modeling changes in ecosystem processes in the laboratory classroom can be logistically difficult and expensive. This complexity often leaves little time for students to generate...

    Keywords: data analysishypothesis testingdata visualizationdata managementMicrobial RespirationDecompostionAbiotic ConditionsResults Communication

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    An Inquiry-Based Project Added to Traditional Labs: Hands-On Fish Awareness Research in Freshwater Systems Conducted by First-Year Biology Students
    This project involves students in an inquiry-based project added to the introductory biology laboratory course for majors in fall 2019. Research has shown that student engagement in authentic...

    Keywords: Evolutionbehaviorichthyology

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    Central Dogma, Dictionaries, and Functions: Using Programming Concepts to Simulate Biological Processes
    Technologies like next-generation sequencing, proteomics, and high-throughput phenotyping have transformed the way we do biology. There is a continued need for scientists with computational skills...

    Keywords: computationpythonJupyter notebookFunctionscentral dogmaDictionaries

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    Engaging Students in Pharmacogenetics: Patient Case Studies Using the PharmGKB Website
    Cytochrome P450 (CYP) enzymes are important regulators of drug efficacy and toxicity. Genetic variation in CYP isoforms can impact how well patients respond to medications or experience unwanted...

    Keywords: toxicologyPharmacologydrug metabolismpharmacodynamicspharmacogenetics

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    Online Information Literacy: Applying the CRAAP Test to Vaccine (Mis)information
    Teaching scientific literacy skills can help combat the propagation of misinformation online. This lesson is intended to give students practice identifying reliable scientific information on the...

    Keywords: Vaccinesimmunityreliability

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    Escape Zoom!: Reviewing Introductory Evolution Content Using an Escape Room Format
    Reviewing and integrating key concepts and learning goals at the end of a biology course can be overwhelming to students and instructors alike. Often end-of-term review sessions in preparation for...

    Keywords: Evolutionartificial selectionSpeciationextinctionsexual selectionphylogenetic treesmechanisms of evolution

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    Exploring Miracle Fruit: An Undergraduate Laboratory Exercise on Experimental Design
    In recent years, undergraduate biology and biochemistry curricula have seen an increase in the use of course-based undergraduate research experiences (CUREs). CUREs maximize potential student gains...

    Keywords: sensory systemspHProtein shapeTaste

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    Learning About Protein Localization: A Lesson for Analyzing Figures in a Scientific Publication
    In order to function correctly, proteins must be localized to a specific subcellular location. We have designed this lesson to use data from the primary literature to teach students about the...

    Keywords: colocalizationimmunofluorescenceProtein localizationsignal sequencessubcellular fractionationwestern blotting

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    Engaging Undergraduates in Mechanisms of Tubular Reabsorption and Secretion in the Mammalian Kidney
    If students fail to see the connections among physiological systems, they can become overwhelmed with the amount of information they need to learn. Some students have particular difficulty with the...

    Keywords: OsmosisActive transportMass flowRenal reabsorptionRenal secretionTransport across membranes

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