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    CRISPR Gene Editing: Designing the gRNA and Donor Template
    In this adaptation, students learn how CRISPR/Cas9 is used in bacterial immunity and gene editing. Students create both a gRNA target and a donor template to edit a gene. Mutations can be from the...

    Keywords: geneticseducationcell biologymolecular biologymutationStem cellsstructure-functionmolecular visualization and analysis3D protein structure /function analysisCRISPR/Cas9crisprDNA mutationPiwiPDBMolecular Case StudyPiwi Matters

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    COVID-19: Molecular Basis of Infection-ADAPTATION
    This case was written in Spring 2020 during the COVID-19 pandemic. It focuses on understanding the structure and interaction of the SARS-Cov-2 viral spike protein that facilitates infection in...

    Keywords: infectionvaccinemolecular visualization and analysisCOVID19PDBSARS-CoVMolecular Case Study

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    Molecular Basis of Sickle Cell Disease
    This multi part case on hemoglobin structure as it relates to oxygen binding and sickle cell disease focuses on utilizing bioinformatics and molecular visualization tools to learn about the sickle...

    Keywords: Hemoglobinmolecular visualization and analysisintroductory bioinformaticssickle cell diseasePDBMolecular Case Studyoxygen bindingmyoglobinmolecular literacy3D protein structuresstructural representations

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    The Happy Blue Baby Hemoglobin
    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved.

    Keywords: mutationHemoglobinmolecular visualization and analysisPDBMolecular Case Study

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    612

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    Nicholas' Story
    This 3 part case on sickle cell disease focuses on visualizing and understanding the molecular basis of its cause, symptoms, complications, management, treatment, and possible cures.

    Keywords: Hemoglobinmolecular visualization and analysissickle cell diseasePDBMolecular Case Study

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    A Case of Severe Insulin Resistance
    This case focuses on understanding how a mutation in a cell signalling protein (a kinase) can prevent insulin function and lead to diabetes.

    Keywords: molecular visualization and analysisPDBMolecular Case Studyinsulin resistance

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    560

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    1

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    Waking up Anna
    This case focuses on understanding the molecular basis of Anna's sleeping disorder and its treatment.

    Keywords: sleepmolecular visualization and analysisPDBMolecular Case StudyGABA

    1347

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    511

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    0

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    1

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    Happy Blue Baby
    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved on its own...

    Keywords: mutationHemoglobinmolecular visualization and analysisPDBMolecular Case Study

    1469

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    538

    downloads

    0

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    3

    adaptations

    Nicholas' Story
    This 3 part case on sickle cell disease focuses on visualizing and understanding the molecular basis of its cause, symptoms, complications, management, treatment, and possible cures.

    Keywords: Hemoglobinmolecular visualization and analysissickle cell diseasePDBMolecular Case Study

    1624

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    510

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    0

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    4

    adaptations

    The Effect of Climate Change on Butterfly Phenology
    In this module, students explain the importance of collections in scientific research, manipulate data in a spreadsheet program, create properly plotted and labeled graphs, analyze data to test...

    Keywords: ExcelResources @ ESA - TIEEclimate changefmnphenologynatural history collectionsDIGbutterflyinterspecific interactions

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    Global Temperature Change in the 21st Century: An Introduction to Global Climate Models and Graphing in Excel (Adapted for Non-Majors)
    Students link human behavior in various climate change scenarios to predicted temperature outcomes at both local (their assigned Latitude) and global (Latitudinal trends) scales. This adaptation is...

    Keywords: ExcelResources @ ESA - TIEEecology labclimate changeenvironmental scienceglobal changehuman-environmental interactionsSimple Linear Regressionhuman impactsinclusive pedagogy-FMN

    1245

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    1503

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    Diving into Deep Sea Data
    A module that combines NOAA's Okeanos Explorer and the iDigBio Portal to explore the deep sea!

    Keywords: Querying databasesremote sensingnatural history collectionsfishesscientific name5ESpeciesichthyologydeep sea

    1244

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    698

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    Birds and Lice: Reciprocal Natural Selection
    This exercise investigates the form and function of lice and their relationship to their bird host.

    Keywords: BiodiversityparasitesbirdsCoevolutionnatural history collections

    1740

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    671

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    Louse and Human Coevolution
    This module examines the complicated co-evolution of Lice, Humans, and Great Apes

    Keywords: phylogeneticsBiodiversityparasitesCoevolutionhuman evolution

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    1863

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    Does Organelle Shape Matter? Exploring Cell Shape through the Allen Cell Explorer and High-content Microscopy Datasets
    The morphology and localization of structures inside the cell are often assumed to fit the ideal images found in biology textbooks. This interrupted case study using high-throughput microscopy data...
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    Cross-Scale Interactions (Project EDDIE)
    Students explore new modeling and computing tools while learning fundamental concepts about how lake phytoplankton blooms occur through cross-scale interactions.

    Keywords: modelingProject EDDIE

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    Biodiversity Literacy in Undergraduate Education (BLUE): Building standards and resources for using collections data in the classroom
    Abstract for poster on using collections data presented at the 2019 BioQUEST & QUBES Summer Workshop

    Keywords: data sciencenatural history collections2019 QUBES/BioQUEST Summer WorkshopBLUE

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    126

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    Predator-Prey Interactions: Selective foraging by wolf spiders
    This interactive case study is intended for use in lower-division biology or ecology courses to complement the SimUText (SimBio) chapter entitled Predation, Herbivory and Parasitism.
    1112

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    Exploring how climate will impact plant-insect distributions and interactions using open data and informatics
    This teaching module provides an entry point for students to learn about data science, open data repositories (e.g., citizen science data), and species distribution modeling to study the effects of...

    Keywords: modelingcitizen sciencehypothesis testingdata scienceclimate changeR programming languageBiodiversityplant animal interactionsinquiry-based learningspecies distributionseco-informatics

    1385

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    2884

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    The Effect of Climate Change on Butterfly Phenology - Intro Environmental Science
    In this module, students practice interpreting the relationship between variables before exploring changes in butterfly phenology through the use of natural history collections data.

    Keywords: ExcelResources @ ESA - TIEEgraphingquantitative literacyclimate changefmnphenologynatural history collectionsDIGbutterflyinterspecific interactions

    1885

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    1003

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