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    Science “Fails”: A Bank of Historical Examples for Learning From Failure in Science
    Learning from failure is critically important to the processes of scientific inquiry, discovery, and invention. However, students are not routinely taught how to reflect on, learn from, and...

    Keywords: metacognitionScience process skillsLearning from failurepower and privilegestudent wellbeing

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    Learning R for Biologists: A Mini Course Grab-Bag for Instructors
    As biology becomes more data driven, teaching students data literacy skills has become central to biology curriculum. Despite a wealth of online resources that teach researchers how to use R, there...

    Keywords: Rdata analysisRStudio

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    Application of a Bacterial Experimental Evolution System to Visualize and Teach Evolution in Action: A Course-Based Undergraduate Research Experience
    Concepts of evolution are typically taught through examples of extremely long timescales, which do not always resonate broadly. Here, we describe a course-based undergraduate research experience...

    Keywords: EvolutionmutationcompetitionNatural Selectionregulationstructure and functionreproductive fitnessgenotype to phenotypehomologs

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    A Laboratory Module That Explores RNA Interference and Codon Optimization Through Fluorescence Microscopy Using Caenorhabditis elegans
    Scientific research experiences are beneficial to students allowing them to gain laboratory and problem-solving skills, as well as foundational research skills in a team-based setting. We designed...

    Keywords: microscopyC. elegansquantitative analysisinquiry-based learninggene expressionRNA interferenceCodon UsageLaboratory Module

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    Teaching Advanced Concepts in Regulation of the Lac Operon With Modeling and Simulation
    Success in biochemistry and other life science courses requires that students understand important biological concepts. One of these concepts is how gene regulation ensures that homeostasis is...

    Keywords: gene regulationinducible operonProkaryotic cellPhosphoenolpyruvate transferase system (PTS)

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    Fly Exercise: A Simple Experiment to Test the Physiological Effects of Exercise on a Model Organism
    Model organisms are commonly used to study and experimentally explore biological processes in ways that are technically or ethically not possible in humans. For this reason, model organisms are an...

    Keywords: exerciseenzyme kineticsmetabolite concentrationmodel speciesphysical activity

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    A CRISPR/Cas Guide RNA Design In Silico Activity
    CRISPR biotechnologies inspired by the Clustered Regularly Interspaced Short Palindromic Repeat RNA-guided nuclease adaptive bacterial immune system have revolutionized biology research and become...

    Keywords: bioinformaticsgene expressiongenetic basis of diseaseCRISPR/Cas9genetic engineeringin silico

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    Using Musical Instruments to Model Negative Feedback in the Hypothalamo-Pituitary-Target Gland Axes
    Homeostasis and negative feedback are crucial, yet difficult, concepts for undergraduates, particularly in the context of the hypothalamo-pituitary axes. This interactive activity was designed to...

    Keywords: cell-cell communicationhomeostasisnegative feedback

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    Using Zebrafish in a Developmental Biology Lab Course to Explore Interactions Between Development and the Environment
    Important learning outcomes for biology students include the ability to develop experiments as well as pull together concepts across their coursework. The field of developmental biology, especially...

    Keywords: toxicologymorphogenesisorganogenesis

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    CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate students
    Providing undergraduate life-science students with a course-based research experience that utilizes cutting-edge technology, is tractable for students, and is manageable as an instructor is a...

    Keywords: bioinformaticsPCRphenotypingCRISPR/Cas9gene editingcloningGenotypingRestriction enzyme

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    CURE-all: Large Scale Implementation of Authentic DNA Barcoding Research into First-Year Biology Curriculum
    Growing calls in science education reform have emphasized wide-scale engagement of first-year undergraduate students in authentic research experiences; however, large course enrollments, inadequate...

    Keywords: phylogeneticsbioinformaticsBiodiversityprocess of sciencetaxonomyPCRDNADNA sequencegel electrophoresis

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    From Dirt to Streptomyces DNA
    The purpose of this semester-long Lesson is to give students an authentic, course-based undergraduate research experience during which they learn basic and advanced microbiological and molecular...

    Keywords: MetabolismAntibiotic productionrRNA genesSecondary metabolitesStreptomyces

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    A Rapid Genetic Screen Using Wisconsin Fast Plants®: A Hands-On Approach to Inheritance of de novo Mutations
    Some concepts in genetics, such as genetic screens, are complex for students to visualize in a classroom and can be cumbersome to undertake in the laboratory. Typically, very large populations are...

    Keywords: mutationInheritancegermlinesomaplant lifecycle

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