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    Cell Cycle and Mitosis
    This module introduces activities that allow students to walk through the cell cycle and mitotic cell division processes. As part of the activities, students learn about and apply knowledge of...

    Keywords: introductory biologyQuantitative reasoningInterdisciplinary STEMquantitative biologyinterdisciplinaryquantitative skillscell functioncell cyclemitosisCell DivisionMitotic Indexcalculating meanstumorNIQBC2. Data and GraphsC4. mathematical modelsC3. Statistical Analysisstandard errormitotic phaseinterphase

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    A virtual laboratory on cell division using a publicly-available image database
    Cell division is a key concept in cell biology. While there are many popular activities to teach students the stages of mitosis, most make use of simple schematics, cartoons, or textbook diagrams....

    Keywords: image analysismicroscopymitosisCellular Processes

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    Mitotic Index and Cell Division
    This module introduces the mitotic index in the context of understanding the dynamics of cell division in the root of a plant. It is intended for an introductory biology audience.

    Keywords: RatiosCell StructureCell GrowthchartCell DivisionMitotic Index

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    1969-Israelsson-Johnsson-Phase-shift in Geotropic Oscillations a Theoretical and Experimental Study
    The paper studies geotropical induced phase-shifts in circumnutations (turning) of Helianthus annus hypocotlys.

    Keywords: plantoscillationdelaycircumnutationturning

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    Using Immunocytochemistry and Fluorescence Microscopy Imaging to Explore the Mechanism of Action of Anti-Cancer Drugs on the Cell Cycle
    Understanding and visualizing the cell cycle and mitosis is an essential concept of cell biology. This multi-week lab module has students investigate the mechanism of action of anti-cancer drugs...

    Keywords: fluorescence microscopymitosisCell StructureCell ImagingImmunocytochemistryQuantitative microscopySTEM skills

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    Understanding the Importance of Microtubules in Normal Cell Division: Chemotherapy Connection
    In introductory courses, students learn about microtubules as important structures but may not engage in a hands-on experience to localize microtubules themselves or to learn about their connection...

    Keywords: cancerCell DivisionimmunofluorescenceMicrotubulesAntibodies

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    6-022-CannibalismPredatorPrey-ModelingScenario
    The Lotka-Volterra model tells us that the prey and predator exhibit a shifted cyclic behavior over time. In this module, we look at modifying this prey-predator model to consider the case when...

    Keywords: stabilitypredator-preyequilibriaoscillationscannibalismphase planesspiral sinks

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    2003-Fay-Graham-Coupled spring equations
    Coupled spring equations for modelling the motion of two springs with weights attached, hung in series from the ceiling are described.

    Keywords: spring massoscillationHooke's Lawcoupled springsperiodicforcing functionphase portrait

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    5-002-RelationshipDynamics-ModelingScenario
    The different possible dynamics of a two-person romantic relationship are modeled -- as a linear two dimensional system of equations -- and analyzed.

    Keywords: love affairRomeo and Juliet

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    2006-Michael_Coleman-Population Modeling with Ordinary Differential Equations
    We will investigate some cases of differential equations population models beyond the separable case and then expand to some basic systems of ordinary differential equations.

    Keywords: population dynamics

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    1-114-EarthClimate-ModelingScenario
    In this modeling scenario, we investigate the Earth's climate using a zero-dimensional energy balance model. Energy balance models are climate models that try to predict the average surface...

    Keywords: climateenergytemperaturelinearizationphase linesenergy balance modelroot finding

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    5-015-RunnersSynchronize-ModelingScenario
    In this modeling scenario we practice finding and classifying equilibria of a one-variable differential equation. We do this in the context of a phase model which is often a simpler way of studying...

    Keywords: predatorAutonomous equationsoscillationcoupled oscillatorsynchronyrunnerpreyKuramato model

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    Does Organelle Shape Matter?: Exploring Patterns in Cell Shape and Structure with High-Throughput (HT) Imaging
    Organelle structure has been studied and visualized for decades; however, publicly available databases that use improved high-throughput microscopy of gene-edited cell lines have recently...

    Keywords: modelingcase studymicroscopystructureOrganellesHigh-throughput (HT)Endoplasmic Reticulum (ER)Fluorescent microscopyHuman Cell Biology

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    Using Yeast to Make Scientists: A Six-Week Student-Driven Research Project for the Cell Biology Laboratory
    Traditionally-trained undergraduate students often lack an understanding of science as an active process that yields the information presented in their textbooks. One result has been a call for...

    Keywords: yeastgrowth curvecell proliferationviability

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    2004-Jones-Song-Thomas-Controlling wound healing through debridement
    In this article, a system of differential equations that models slough/wound interaction is developed.

    Keywords: bacteriawound healinghealingderidingisocline

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    2003-Fay-Graham-Coupled spring equations
    Coupled spring equations for modelling the motion of two springs with weights attached, hung in series from the ceiling are described.

    Keywords: massoscillationspring\coupled springsperiodicfporcing

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    1-137-SheepGraze-ModelingScenario
    In this activity, students will apply graphical analysis (such as phase lines) to determine the long-term predictions of a differential equation model for pasture grass using two different formulas...

    Keywords: herbivoreplantphase linesbifurcationoverexploitationsheepgraze

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    1-139-PlantsVsHerbivores-ModeliongScenario
    In this activity, students will apply a variety of techniques for analyzing nonlinear systems (e.g., nullclines, linearization, and technologies for drawing phase portraits) to study...

    Keywords: ecologynullclinesherbivoreplant-herbivore interactionsplantlinearization

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    6-011-HumansVsZombies-ModelingScenario
    Students analyze the SIR differential equations model in the context of a zombie invasion of a human population. Students analyze a two equation system representing only two populations, humans...

    Keywords: zombiesinfectionSIR models

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    Linkage Analysis
    This Excel workbook simulates a linkage analysis problem with up to four alleles. Based on the offspring produced by a multihybrid testcross, the user builds a model of the gene order,...

    Keywords: recombinationlinkage analysis

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