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    2006-Loyd-Wodarz-Drug Resistance in Acute Viral Infections-Rhinovirus as a Case Study
    We develop an epidemiological model that can be used to address the spread of resistance at the population level, and a virus dynamics model that can be used to study the dynamics of virus over the...

    Keywords: stabilityresistancevirusdrugepidemic competitionimmune responserhinovirus

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    1989-R_Blickhan-Spring Mass Model For Running-Hopping
    A simple spring—mass model consisting of a massless spring attached to a point mass describes the interdependency of mechanical parameters characterizing running and hopping of humans as a function...

    Keywords: spring massjumpjumping

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    1968-Wagner-Aghajanian-Bing-Correlation of performance test scores with tissue concentration of lysergic acid diethylamide
    This paper offers a two compartment model of lysergic acid diethylamide (LSD) in volunteer students and through parameter estimation models the amount of LSD in the tissue after its initial...

    Keywords: LSDcorrelation coefficientcompartment modellysergic acid diethylamideperformancetest scoretissue concentration

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    2001-A_Tsoularis-Analysis_of_logistic_growth_models
    The paper presents an historical development of the logistic equation in its various forms, including Verhulst, Pearl and Reed, Gompertz, Bertalanffy, Richards, and others.

    Keywords: logisticpopulationgrowth curvelimited growthGompertzhistorylogistic equationVerhulstPearl and ReedBertalanffyRichards

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    2019-Radulescu-Lundgren-A_pharmacokinetic_model_of_lead_absorption_and_calcium_competitive_dynamics
    We build and analyze a compartmental model of lead pharmacokinetics, focused specifically on addressing neurotoxicity.

    Keywords: QUBES Leadership Teamparametersabsorptionbifurcationpharmacokineticscalciumcognitive decline

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    3-103-PullBackCars-ModelingScenario
    This activity offers analysis of a toy pull-back car: solution of a differential equation from model; data collection and parameter estimation; and adapting the model to predict maximum speed and...

    Keywords: modelingdynamicshands-ontoypull-back carpullback

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    5-010-DNADegradation-ModelingScenario
    We ask students to use the system of first order linear differential equations given in a source paper and estimates of the data from laboratory procedures from a plot to estimate the parameters...

    Keywords: DNA\kinetisplasmaratpharmacokinetis

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    5-015-RunnersSynchronize-ModelingScenario
    In this modeling scenario we practice finding and classifying equilibria of a one-variable differential equation. We do this in the context of a phase model which is often a simpler way of studying...

    Keywords: predatorAutonomous equationsoscillationcoupled oscillatorsynchronyrunnerpreyKuramato model

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    9-020-HeatDiffusion-ModelingScenario
    This project guides students through experimental, analytical, and numerical techniques for understanding the heat (diffusion) equation with nonhomogeneous boundary conditions. In particular,...

    Keywords: laboratoryDiffusionheat

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    A Kinesthetic Modeling Activity to Teach PCR Fundamentals
    Most molecular biology and biological sciences students understand that the polymerase chain reaction (PCR) is used to amplify DNA. However, we have found that some students experience conceptual...

    Keywords: PCR

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    Fitting Exponential and Logistic Growth Models to Bacterial Cell Count Data
    In this activity, students will model a noisy set of bacterial cell count data using both exponential and logistic growth models. For each model the students will plot the data (or a linear...

    Keywords: modelingdata analysislinear regressiongraphingExponentsoptimizationcalculusInterpreting GraphsFunctionsqbccCellular and Molecular BiologyChoosing modelsUnderstanding ratesConcepts in Statisticsmeasurementsmanipulating equationscreating graphsExponential and Logarithmic Functionsinterpreting tables

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    Quantifying Bacterial Growth in the Guts and Hemolymph of Fruit Flies: Mathematical Modeling and Data Interpolation/Extrapolation
    In this activity, students will analyze raw data obtained from an experiment that explores the effect of overexpressing the Ssk protein in order to strengthen the intestinal barrier and prevent...

    Keywords: graphingexponential growthlinear modelsqbccinterpolationConcepts in Statistics and Precalculus Understanding exponential rates and linear slopesExtrapolation

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    2006-Cooke-Elderkin-Huang-Predator-Prey interactions with delays due to juvenile maturation
    This paper focuses on predator-prey models with juvenile/mature class structure for each of the predator and prey populations in turn, further classified by whether juvenile or mature individuals...

    Keywords: predator-preyhost-parasitebifurcationage structrematuration delay

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    2005-Minna_Wedenberg-Pharmacokinetic modeling of gastric emptying
    The development of new drug substances is a complex, time consuming and expensive process. Reducing the time for drug development and avoiding late termination of candidate drugs are important...

    Keywords: paracetamolpharmacokineticsstomachsmall intestinesulfapyridine

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    1980-Peastrel-Lynch-Armenti-Terminal_velocity_of_a_shuttlecock_in_vertical_fall
    This paper offers a set of data on a falling shuttlecock (the moving object in badminton) in air. How the authors collected the data is described fully and can be replicated easily by modern...

    Keywords: parameter estimationdata collectionresistancefallingterminal velocityNewton's Second Law of Motionshuttlecock

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    Mosquito Invasion! A Lotka-Volterra Competition Case Study
    In this instructor-led interrupted case study, students practice interpreting Lotka-Volterra competition model parameters using data on an invasive and native mosquito species.
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    Using Open-Source Bioinformatics and Visualization Tools to Explore the Structure and Function of SARS-CoV-2 Spike Protein
    The relationship between protein structure and function is a foundational concept in undergraduate biochemistry. We find this theme is best presented with assignments that encourage exploration and...

    Keywords: bioinformaticsmolecular modelingCOVID19protein structure and functionUCSF ChimeraSARS-CoV-2 spike proteinACE2 receptor

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    Box of Lessons: A Toolkit for Introducing Students to Biomolecular Structure and Function
    This is a poster describing a collection of open educational resources that were developed by faculty participating in the Molecular CaseNet Faculty Mentoring Network in Spring 2022. The collection...

    Keywords: bioinformaticsbiomolecular structureProtein Data Bankresources @ Molecular CaseNet

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    Building Biodiversity Datasets for Invasive Species
    A module guiding students through the process of mapping biodiversity data and building a biodiversity dataset to study the spread and impacts of the invasive aquatic plant species, European...

    Keywords: Management Of Datanatural historyField researchconservation ecologyAquatic invasive speciesbiodiversity informatics

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    A Pipeline in Paradise
    I incorporated fracking into the case study instead of just focusing on building a pipeline, which allowed us to discuss fracking with this case study.
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