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    National Center for Case Study Teaching in Science resource on the 2014 Ebola epidemic. This resource is also included in the NIBLSE Learning Resource Collection

    Keywords: infectious diseaseexperimental designbioinformaticsEbolaNIBLSECase It!PCRBLASTmultiple sequence alignmentPublished in National Center for Case Study Teaching in Sciencepolymerase chain reactionfebrile illnessvirusELISAenzyme linked immunosorbent assayfilovirusAfrica

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    Tackling "Big Data" with Biology Undergrads: A Simple RNA-seq Data Analysis Tutorial Using Galaxy
    Analyzing high-throughput DNA sequence data is a fundamental skill in modern biology. However, real and perceived barriers such as massive file sizes, substantial computational requirements, and...

    Keywords: bioinformaticsDNA sequenceRNAseqgene expression

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    From Cre/LoxP to Fate Maps: Inclusive and Equitable Approaches for Engaging Developmental Biology Students in Experimental Design
    Engaging first generation underrepresented minority students in the process of inquiry in developmental biology is important to increase diversity in future graduate STEM education. One important...

    Keywords: experimental designC. elegansCre/LoxPFate mapheart developmentheart regenerationmousereporter constructzebrafish

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    When tests disagree, how do I know if I have COVID-19?
    Students will learn about infectious disease and the immune response to infection by investigating different types of tests (PCR, antigen, and antibody tests) to detect the SARS-CoV-2 viral genetic...

    Keywords: geneticsVision and Changeintroductory biologyinfectious diseasemolecular biologycore competenciesRT-PCRviruscore conceptsnon-majors biologySARS-CoV-2antibodyAntigenImmunoReachmolecular DiagnosticsCOVID-19 transmission

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    Linear Regression (Excel) and Cellular Respiration for Biology, Chemistry and Mathematics
    Students typically find linear regression analysis of data sets in a biology classroom challenging. These activities could be used in a Biology, Chemistry, Mathematics, or Statistics course. The...

    Keywords: statisticsmathematicsdata analysisdatalinear regressionbiologyonlinegraphinglinear equationsQuantitative reasoningassessmentcollege algebracellstatistical analysisregressionOERAlgebrachemistryModelscorrelationSimple Linear RegressionMicrosoft Excellab activityexperimentCellular ProcessesATPqbccUsing Excelmanipulate equationsCellular and Molecular BiologyConcepts in Statisticsoxidationline of best fitexplaining statisticsusing statisticsCellular RespirationPredictionsRespirationgraphing in ExcelLinear CorrelationExothermic Reactioncreate scatter plotAdenosine Triphosphate (ATP)germinating peasPre-lab activityStudent activityHybridCollecting DataR-squareRegression ModelFunctionDependent VariablesIndependent VariablesLinear EquationLinear Equation in two variablescreate graphcreate equationcreate regressioncreate plotinterpret regressioninterpret data

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    A Team-Based Approach to Course Development Involving Undergraduate Researchers
    Development of an undergraduate laboratory course can be a challenge, because of the need to balance both logistical and pedagogical considerations. We piloted a team-based approach to developing...

    Keywords: student researchcourse development

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    The Great Petunia Carnage of 2017: A Clicker Case Study Using Petunias to Describe the Effect of Genetic Modification on the Biochemistry of Flower Color and Phenotype in Plants
    In this single class period case study, students examine the difference between genotype and phenotype by studying the mechanisms by which commercially available petunias have been bred to have...

    Keywords: case studyGenetic ModificationsBiochemistry of Flower ColorGMO regulationsGenotype-Phenotype Connections

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    Drawing flowcharts of lab protocols helps students prepare for biology labs
    With the publishing of the Vision and Change report, we know it is best practice to include authentic research experiences in our undergraduate science lab classes. One big challenge in teaching...

    Keywords: laboratorymolecular biologyUndergraduateprotocolflowchart

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    Teaching the Central Dogma Using a Case Study of Genetic Variation in Cystic Fibrosis
    The central dogma of biology is a foundational concept that is traditionally included in genetics curricula at all academic levels. Despite its ubiquitous presence throughout genetics education,...

    Keywords: transcriptioncentral dogmatranslationsequence analysisDNA replicationgenetic variants

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    Introduction to nucleotide sequence analysis and protein modeling in MEGA and PyMol using coronavirus SARS-CoV-2
    Introduction into computational approaches in phylogeny and protein modeling based on coronavirus SARS-CoV-2 (caused COVID-19 pandemic). Two self-guided tutorials for standard lab classes of 2.5...

    Keywords: phylogeneticsundergraduate educationbioinformaticsNCBICOVID19coronavirusMEGAPyMolvirtual labPDBprotein modelingSARSSARS-CoV

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    Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson
    There is a growing need for integration of “Big Data” into undergraduate biology curricula. Transcriptomics is one venue to examine biology from an informatics perspective. RNA sequencing has...

    Keywords: bioinformaticscancertranscriptomicshigh-throughputData wranglingSingle cell RNA sequencingq

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    CRISPR in the Classroom Network - Bringing CRISPR-Cas9 technologies to the undergraduate classroom: an undergraduate instructors' network (RCN Introduction)
    Our RCN-UBE seeks to develop a national network for the development and implementation of experiential-based course modules for undergraduates centered around CRISPR-Cas9 technology through...

    Keywords: RCN-UBE Introduction

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    2006-Wilensky-Reisman-Thinking Like a Wolf a Sheep or a Firefly
    We describe a computation-based approach that enables students to investigate the connections between different biological levels using agent-based, embodied modeling tools.

    Keywords: simulationNetLogopredator-preyagent-basedwolffox

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    2006-Juska-Gedminiene-Ivanec-Growth of Microbial Populations-Mathematical Modeling-Laboratory Exercises-Model-Based Data Analysis
    The aim is to teach the students to use a fresh approach to the problems they are familiar with, to come up with an articulate verbal model after a mental effort, to express it in rigorous...

    Keywords: population growth ratelogistic equationVerhulst equationgeneration timelag time

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    Developing a phylogram from computational resources.
    This laboratory module, published on CourseSource, leads introductory biology students in the exploration of a basic set of bioinformatics concepts and tools.

    Keywords: phylogeneticsbioinformaticssequencingFASTANCBINIBLSEalgorithmsBLASTmultiple sequence alignmentsequence similarityneighbor-joining distance matrixCourseSourcephylogrampercent identity matrix

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    The Perfect Brew: An Activity Demonstrating Cell Counting and Hemocytometer Use
    In this activity, students will explore the use of a hemocytometer for counting cells, demonstrate the relationship between the grid seen in the microscope with volume of liquid in suspension and...

    Keywords: RatiosmicrobiologyqbccCellular and Molecular BiologyUnderstanding fractionsconverting unitschanging scalesmeasurements

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    Teaching about fatherless snakes in a prison classroom
    Developing a course for the first time as a graduate student is challenging. When I first taught introductory biology with the Cornell Prison Education Program, I struggled to design and adapt...

    Keywords: meiosismitosisReproduction

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    Investigating Gene Expression and Cell Specialization in Axolotl Embryos
    The process of cell specialization is critical to the formation and function of tissues in animals and plants. Although gene expression, including the regulation of transcription, is taught in most...

    Keywords: developmenttranscriptiongene expressionmodel organismembryo

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    Isolation and Functional Analysis of a Pancreatic Enzyme in an Introductory Student Lab
    Structure and function are correlated at all levels of biology. This topic is typically addressed early in an undergraduate class in general or molecular biology before students have gained much...

    Keywords: Protein StructureproteaseEnzymechemical bondscatalysissolubility

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    A Close-Up Look at PCR
    The Polymerase Chain Reaction (PCR) is a fundamental laboratory technique that allows for the amplification of many copies of a desired DNA target sequence. Despite its prevalence, undergraduate...

    Keywords: PCRDNA replication

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