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    Defining and Understanding Pathogenic Disease: An Engaging Activity that Connects Students' Lived Experiences with their Academic Studies
    Contagious diseases are unavoidable realities of life. Thus, understanding pathogens and their respective diseases is important in many biological subfields including evolution, ecology, health...

    Keywords: infectious diseasePathogenspathogenic disease

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    Good Drug, Bad Practice: Tackling the Ivermectin Fiasco
    Throughout history, biomedical advancements have alleviated suffering worldwide and significantly advanced human well-being. As researchers and educators, we are well-familiar with the...

    Keywords: Peer reviewCOVID19fraudtherapeutic drugIvermectin

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    2017-GR_Gustafson-Differential Equations Course Materials
    There are many applications from compartment and cascade analysis, recycling brine tank, home heating with multiple rooms, chemostat, microbes, heartbeats, lidocaine, nutrient flow in an aquarium,...

    Keywords: chemostatmicrobesbiomassforecastingtransfercompartmentpesticidesearthquaketankheatinglidocainebrineheartbeatsnutrient flowaquariumelectric networkscircuitsloggingbuildingcascade

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    2014-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
    To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for...

    Keywords: metabolic syndromecompartment modelcholesterolhigh blood cholesterol

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    2017-Brandi-Garcia-Motivating engineering students to math classes - Practical experience teaching ODEs
    In this paper we propose an approach to teaching-learning process of mathematical concepts to engineering students with a motivational factor: a practical problem to be modeled in which students...

    Keywords: computational toolsteachingengineering studentspractical problem

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    2016-Manheim-EtAl-Improving Decision Support for Infectious Disease Prevention and Control
    This report describes decision-support tools, including models and nonmodeling approaches, that are relevant to infectious disease prevention, detection, and response and aligns these tools with...

    Keywords: infectious diseaseecosystemepidemicmodel policy

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    2015-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
    To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for...

    Keywords: metabolic syndromecholesterolhigh blood cholesterolcholesterol homeostasis

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    2014-Wang-EtAl-Estimating Mixed-Effects Differential Equation Models
    When multiple replicates of measurements are available for the dynamic process, it is of great interest to estimate mixed-effects in the ODE model for the process. We propose a semiparametric...

    Keywords: pharmacokineticsdynamic modelssmoothingsplinemixed-effects modelsHiV combination therapy

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    2013-Greer-EtAl-Collaborative Understanding of Cyanobacteria in Lake Ecosystems
    We describe here a collaboration in which the mathematicians help collect data, the ecologists synthesize more data from model output than they can produce empirically, and the collaboration...

    Keywords: collaborationlakeecosystemcyanobacteriafield workcolonyGloeo

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    2011-Yanyu_Xiao-Study of Malaria Transmission Dynamics by Mathematical Models
    The novelty lies in the fact that different distribution functions are used to describe the variance of individual latencies. The theoretical results of this project indicate that latencies reduce...

    Keywords: infectious diseaseinfectionmalarialatencyspatial dispersalmulti-species

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    2011-Brian_Winkel-Parameter Estimates in Differential Equation Models for Population Growth
    We estimate the parameters present in several differential equation models of population growth, specifically logistic growth models and multiple species competition models.

    Keywords: logisticpopulationparameciaGausegradient search

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    2010-Shianga-EtAl-Computational model of the human glucose-insulin regulatory system
    A computational model of insulin secretion and glucose metabolism for assisting the diagnosis of diabetes mellitus in clinical research is introduced. The

    Keywords: glucose tolerance testsum of squared residualsmultiple shooting methodcost function

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    2010-Roberto_Munoz-Alicea-Mathematical Model for Enzyme Kinetics-Multiple Timescales Analysis
    We study a basic model for enzyme substrate reaction. Through several assumptions and via nondimensionalization, we simplify the equations.

    Keywords: kineticsEnzymesubstratenondimensionalizationmultiple timescales

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    2009-Su-EtAl-Fitting Compartmental Models to Multiple Dose Pharmacokinetic Data using SAS
    In the case of a multiple dose study where subjects experience different dosing times, a superposition principle can be used to recursively account for each additional dose.

    Keywords: SASsuperpositionpharmacokineticscompartmental modelsmultiple dose

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    2008-Huangi-Lu-Modeling long-term longitudinal HIV dynamics with applications to an AIDS clinical study 
    To better understand the factors responsible for the virological failure, this paper develops the mechanism-based nonlinear differential equation models for characterizing long-term viral dynamics...

    Keywords: longitudinal dataAIDSantiretroviral drug therapyBayesian nonlinear mixed-effectstime-varying drug efficacyHIV dynamics

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    Engaging Students in Pharmacogenetics: Patient Case Studies Using the PharmGKB Website
    Cytochrome P450 (CYP) enzymes are important regulators of drug efficacy and toxicity. Genetic variation in CYP isoforms can impact how well patients respond to medications or experience unwanted...

    Keywords: toxicologyPharmacologydrug metabolismpharmacodynamicspharmacogenetics

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    2007-Helfgott-Seier-Some Mathematical and Statistical Aspects of Enzyme Kinetics
    We will analyze some basic ideas behind enzyme kinetics, which allow us to deal with separable and linear differential equations as well as realize the need to use power series.

    Keywords: kineticsEnzymeexperimental dataregresion

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    2006-Wilensky-Reisman-Thinking Like a Wolf a Sheep or a Firefly
    We describe a computation-based approach that enables students to investigate the connections between different biological levels using agent-based, embodied modeling tools.

    Keywords: simulationNetLogopredator-preyagent-basedwolffox

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    2006-Shigui_Ruan-Delay differential equations in single species dynamics
    In this survey, we shall review various delay differential equations models arising from studying single species dynamics.

    Keywords: allee_effectdelayed biological systemsfood limitperiodiciityrecruitment modelRegulation of Haematopoiesis

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    Discovery and Invention: A Reflection on Representation in Science
    Despite increased awareness of the lack of equity and inclusion in the STEMM classroom, lessons on DEI topics are treated as separate to the scientific curriculum being taught. Rarely are...

    Keywords: EquityDiversity and Inclusionantiracism

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