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    Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Introductory Biology (identifying new promoters)
    Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression. This laboratory lesson allows students to...

    Keywords: bacteriasynthetic biologygene regulationtranscriptionstudent researchcentral dogmacloningpromoterreporter gene/protein

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    The Lecture-Free Classroom: Teaching students backward design and Bloom's Taxonomy to create their own learning environment
    We describe Presentation Enhanced Learning (PEL), a flexible, lecture-free, field-tested teaching format to promote problem-based, active learning in upper-division or graduate biological sciences...

    Keywords: active learningbackward designProblem based learningBloom's Taxonomy

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    Building a Model of Tumorigenesis: A small group activity for a cancer biology/cell biology course
    The multistep nature of tumorigenesis is a foundational concept in the context of Cancer Biology. Many students do not appreciate the complex nature of cancer development nor do they understand how...

    Keywords: pathwayscancerMolecular AlterationsRetrospective dataTumorigenesis

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    Why do Some People Inherit a Predisposition to Cancer? A small group activity on cancer genetics
    Before undergraduate students take a genetics course they generally know cancer has a genetic basis and involves the proliferation of cells; however, many are uncertain about why only a subset of...

    Keywords: cancerInheritance patternsProbability calculationProto-oncogeneTumor Suppressor Gene

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    The Science Behind Parthenogenesis: Interesting things happen when meiosis goes “wrong”
    Parthenogenetic reproduction is a fascinating, complex topic.  This article accompanies “Why Meiosis Matters: The case of the fatherless snake.” It summarizes the basic information...

    Keywords: meiosismitosissex determinationAsexual reproductionParthenogenesis

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    Using Linear Regression Adaptation: Exploring Vector-borne diseases in an online classroom
    In this adaptation students in online classrooms will use linear regression at home and in synchronous online time to analyze real data on vector-borne diseases and explore how environmental...

    Keywords: ecologygraphingmicrobiologyqbccUnderstanding ratesCreate graphsInterpret graphsinterpret tablesConcepts in Statistics

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    Mol* Adaptation: Case of Severe Insulin Resistance
    This is an adaptation using Mol* on the original case written. This case focuses on understanding how a mutation in a cell signalling protein (a kinase) can prevent insulin function and lead to...

    Keywords: molecular visualization and analysisPDBMolecular Case Studyinsulin resistanceMol*MolStar

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    Ecology of Infectious Disease: Data Mining the National Notifiable Diseases Surveillance System (NNDSS) for Ecological Patterns
    How to use publicly available infection case data to teach ecology and evolution of human infectious diseases.

    Keywords: Evolutionecologyinfectious diseasehumansjigsawsmall group workEvolutionary medicinedata explorationCDCNNDSS

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    Choosing healthy data for healthy relationships: how to use 5-point summaries, box and whisker plots, and correlation to understand global health trends.
    This module utilizes a user-friendly database exploring data selection, box-and-whisker plot, and correlation analysis. It also guides students on how to make a poster of their data and conclusions.

    Keywords: Querying databasesgraphingRatiosdata typesstatistical learningcorrelationBox Plotsqbcchealth sciences education researchnutrition & food scienceUnderstanding ratesCreate graphsInterpret graphsinterpret tablesHealth ScienceConcepts in Statisticsexplaining statisticsusing statistics

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    Happy Blue Baby
    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved on its own...

    Keywords: mutationHemoglobinmolecular visualization and analysisgenetic basisPDBMolecular Case StudyMol*

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    Happy Blue Baby: MCQs for large classes
    Multiple choice questions for the Happy Blue Baby case study pre-work

    Keywords: mutationHemoglobinmolecular visualization and analysisPDBMolecular Case Study

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    Plate Tectonics: GPS Data, Boundary Zones, and Earthquake Hazards (Project EDDIE)
    Students work with high precision GPS data to explore how motion near a plate boundary is distributed over a larger region and hypothesize the area over which boundary-related earthquake hazards...
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    Graphing bacterial growth rates: semi-log graphs v linear graphs
    In this activity, students will explore the concept of binary fission, generation time, and bacterial growth curves, with an emphasis on the log phase. Students will use semi-log graphs and linear...

    Keywords: graphingexponential growthMicrobiology Educationmicrobiologybacteriagrowth rateUndergraduate STEM educationCommunity College Educationqbccmanipulate equationsCellular and Molecular BiologyCreate graphsInterpret graphsbinary fissionsemi-log graphlinear graphgrowth curvecreating graphsExponential and Logarithmic Functions

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    Investigating Evidence for Climate Change (Project EDDIE) with CO2 and 13CO2 data: adapted for R
    This is an adaptation to work in R of Investigating Evidence for Climate Change (Project) by Hage, M. 2020. Students will investigate geologic and modern evidence for global temperature and...

    Keywords: climate changeGlobal Temperature Changeco2ice core datastable isotopesR software

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    Using Linear Regression to Explore Environmental Factors Affecting Vector-borne Diseases
    In this activity students will use linear regression to analyze real data on vector-borne diseases and explore how environmental factors such as climate change or population density influence the...

    Keywords: ecologygraphingmicrobiologyqbccUnderstanding ratesCreate graphsInterpret graphsinterpret tablesConcepts in Statistics

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    Flying With Swallows – a Model for Undergraduate Research-Based Learning
    Moreno Valley College, a two-year community college in Southern California, experiences an annual migration of cliff swallows. The presence of these birds inspired the development of the...

    Keywords: researchresearch-based classroom instruction

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    Atlas of Black Scholarship for Inclusive and Racially Diverse STEM Curricula – Volume I
    The contributions of Black scientists to the advancement of STEM are poorly represented in course materials. Here, we provide an Atlas of Black Scholarship to help Life Sciences and Chemistry...

    Keywords: BLACK SCIENTISTS IN STEMRACIALLY-RESPONSIVE PEDAGOGYBIOLOGY AND CHEMISTRY EDUCATIONDIVERSITY IN STEM CURRICULUM

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    Implementing a Math Prerequisite - Does it help or hurt?
    Poster on the effect of math prerequisite courses on student success in introductory biology. Presented at the 2020 BIOME Institute: Cultivating Scientific Curiosity

    Keywords: introductory biologymath prerequisite

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    CRISPR Gene Editing: Designing the gRNA and Donor Template
    In this adaptation, students learn how CRISPR/Cas9 is used in bacterial immunity and gene editing. Students create both a gRNA target and a donor template to edit a gene. Mutations can be from the...

    Keywords: geneticseducationcell biologymolecular biologymutationStem cellsstructure-functionmolecular visualization and analysis3D protein structure /function analysisCRISPR/Cas9crisprDNA mutationPiwiPDBMolecular Case StudyPiwi Matters

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    Sickle Cell Anemia using Nicholas’ Story
    The goal of this exercise is to introduce students to 3-D structures of biological molecules, visualize and manipulate them to understand their functions. The exercise also helps them see the...

    Keywords: Hemoglobinsickle cell diseaseMolecular Case Study

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