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    2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
    This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.

    Keywords: absorptioncompartmentbloodstreamplasmapharmacokineticspharmacodynamicstherapeutic concentration rangedrug dispositiondrug response

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    2016-Mehmet_Pakdemirli-Mathematical design of a highway exit curve
    Using fundamental principles of physics and calculus, the differential equation determining the curve function is derived.

    Keywords: kinematicscurve designhighway exittangential acceleration

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    2016-Lewnard-Townsend-Climatic and evolutionary drivers of phase shifts in the plague epidemics of colonial India
    Our analysis shows that historical datasets can yield powerful insights into the transmission dynamics of reemerging disease agents with which we have limited contemporary experience to guide...

    Keywords: infectious diseasepVector-Borne Diseaselagueplague

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    2015-Sebesyen-Farago-Invasive Species Model with Linear Rat Harvesting on Easter Island
    In this paper we suggest a natural modification of this model. Namely, we will investigate the case where the amount of the rats is decreased due to some external factor, e.g., exterminations by...

    Keywords: carrying capacityharvestEaster Islandinvasie especiesratsRoughgarden theorem.

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    2004-Ledzewicz-Schattler-Application of Control Theory in Modelling Cancer Chemotherapy
    In this paper we discuss how to incorporate more realistic medical aspects of chemotherapy which hitherto have been neglected in the models.

    Keywords: optimal controldrug resistancepharmacokineticspharmacodynamicschemotherapy

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    2015-Cano-EtAl-Bringing partial differential equations to life for students
    This work describes how to use an authoring tool, Easy Java Simulations, to build interactive simulations using FreeFem++ (Hecht F 2012 J. Numer. Math. 20 251) as a PDE solver engine.

    Keywords: Java SimulationFreeFemauthoring toolsauthoring methodsphysical modellingclassroom teaching

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    2014-Groetsch-Yost-Vertical Projection in a Resisting Medium - Revelations on Observations of Mersenne
    This article, inspired by a 17th-century woodcut, validates empirical observations of Marin Mersenne (1588–1648) on timing of vertically-launched projectiles for a general mathematical model of...

    Keywords: resistanceprojectile

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    2013-Alicia_Caldwell-Students Rise to the Challenge of Modeling Yeast Growth Despite Sour Hiccups from Imperfect Data
    This paper describes a lab in which students in an Applied Mathematics in Biology course observe the growth of Saccharomyces cerevisiae, a yeast strain, in differing sugar concentrations for use in...

    Keywords: Saccharomyces cerevisiaelogisticyeastdeathgrowthsugaralcohol

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    2012-Shargel-Yu-AccessPharmacy-Applied Biopharmaceutics and Pharmacokinetics
    Step by step formation of drug absorption models is shown with many good graphics of system and plots. Solutions are offered but no solution methods are shown.

    Keywords: Michaelis-MentenEnzymesubstratecompartmentpharmacokineticsrate constanturinary dataabsorption rate

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    2010-Jungck-EtAl-Mathematical Manipulative Models-In Defense of Beanbag Biology
    This paper offers up samples of projects from the Bio- QUEST Curriculum Consortium’s 24-yr experience of holding faculty development workshops for biology and mathematics educators.

    Keywords: epidemiologysimulationinfectious diseasedisease transmissiondiseasein-class activitybean bag activity

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    2010-Del-Ciello-EtAl-Modeling Disease
    We model the transmission of a disease through a population. Such modeling is very important to the study of epidemiology and the practice of medicine.

    Keywords: diseasespreadcarriessymptomaticasymptomatic

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    2009-Schaffer-Bronnikova-Controlling malaria
    The present paper reviews potential control strategies from the viewpoint of mathematical epidemiology.

    Keywords: epidemiologymalariabifurcationmosquitotransgenic mosquitoes

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    2008-Ribbing-EtAl-Mathematical models of diabetes progression
    Writing a good model for diabetes progression is difficult because the long time span of the disease makes experimental verification of modeling hypotheses extremely awkward. underlying the

    Keywords: physiologyclinical trialsdiabetesdiabetes progression

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    2008-Lawson-Marion-An Introduction to Mathematical Modelling
    This is a broad based set of notes with sections: Building Models, Studying Models, and Using Models. No depth on any model, no solution strategies, but good references to models, and general...

    Keywords: time serieslinear regressionAkaike Information Criterionmcomparision models

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    2008-Huangi-Lu-Modeling long-term longitudinal HIV dynamics with applications to an AIDS clinical study 
    To better understand the factors responsible for the virological failure, this paper develops the mechanism-based nonlinear differential equation models for characterizing long-term viral dynamics...

    Keywords: longitudinal dataAIDSantiretroviral drug therapyBayesian nonlinear mixed-effectstime-varying drug efficacyHIV dynamics

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    2008-Chernyshov-EtAl-The Problem of Modelling of Economic Dynamics in Differential Form
    The authors have tried to analyze procedures of the construction of differential equations that are employed for modeling of macroeconomic processes. The results prove to be rather unexpected.

    Keywords: Fredholm integral equation ofLeontief’s modelmacroeconomic processes

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    2007-Mogen_Steffensen-Differential Equations in Finance and Life Insurance
    The mathematics of finance and the mathematics of life insurance were always intersecting. Life insurance contracts specify an exchange of streams of payments between the insurance company and the...

    Keywords: financedisabilitylife insurancemortalityinsuraneThiele’s equationBlack-Scholes equation

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    Engaging Students in Pharmacogenetics: Patient Case Studies Using the PharmGKB Website
    Cytochrome P450 (CYP) enzymes are important regulators of drug efficacy and toxicity. Genetic variation in CYP isoforms can impact how well patients respond to medications or experience unwanted...

    Keywords: toxicologyPharmacologydrug metabolismpharmacodynamicspharmacogenetics

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    2007-Exben_Friis-Jensen-Modeling and Simulation of Glucose-Insulin Metabolism
    In this thesis one of the models of diabetes, Bergman’s minimal model is described trough derivation and simulations.

    Keywords: Metabolisminsulin resistanceglucosePID controllerintolerance

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    2006-Michelle_LeMasurier-Nonstandard Topics for Student Presentations in Differential Equations
    An interesting and effective way to showcase the wide variety of fields to which differential equations can be applied is to have students give short oral presentations on a specific application.

    Keywords: Presentationstudent presentation

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