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    Understanding the Importance of Microtubules in Normal Cell Division: Chemotherapy Connection
    In introductory courses, students learn about microtubules as important structures but may not engage in a hands-on experience to localize microtubules themselves or to learn about their connection...

    Keywords: cancerCell DivisionimmunofluorescenceMicrotubulesAntibodies

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    5-007-ChemOpt-ModelingScenario
    Modeling a chemical reaction and estimating parameters in the model permits optimization of profits from extracting reactants.

    Keywords: optimizationpYield and sustainabilitynonprofit managementLaw of Mass Actionkineticreaction

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    2020-TeachingModule-SpringDesignToMeetSpecsAtMinimumCosts
    We discuss a Modeling Scenario in which students are asked to design a spring mass system at minimum costs give relative costs of features of the spring.

    Keywords: moduleoptimizationspring massmassspring\costTeaching Moduleminimal cost

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    6-005-InsectColonySurvivalOpt-ModelingScenario
    We present a system of nonlinear differential equations to model the control of energy flow into producing workers or reproducers in an insect colony, using a set of given parameters and a number...

    Keywords: optimizationOptimal Control Theoryinsect colonyoptimal controlnatural resourcesPointryagin's Maximum Principlecontrol variable

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    2018-Akman-EtAl-Parameter Estimation in Ordinary Differential Equations Modeling via Particle Swarm Optimization
    We demonstrate Particle Swarm Optimization efficacy by showing that it outstrips evolutionary computing methods previously used to analyze an epidemic model.

    Keywords: epidemicParticle Swarm Optimizationoptimize parameters

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    2017-Sim-EtAl-Optimal control of a coupled tanks system with model-reality differences
    In this paper, an efficient computational approach is proposed to optimize and control a coupled tanks system.

    Keywords: optimal controlflowtankscoupled tanks

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    2017-Jun_Liu-Hammer Throwing parameters optimization model research based on flight dynamical differential equation
    With progress of times, sports techniques are also rapidly developing, in order to let Chinese hammer throwers more quickly improve themselves levels.

    Keywords: sportsprojectilehammer throwrelease angle

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    2017-D_Goulet-Modeling, Simulating, and Parameter Fitting of Biochemical Kinetic Experiments
    In many chemical and biological applications, systems of differential equations containing unknown parameters are used to explain empirical observations and experimental data. The differential...

    Keywords: optimizationBiochemistrysensitivity analysischromatographymass actioncluster analysisconservation lawsdimerizationestrogen receptor protein

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    2017-Agmour-EtAl-Optimization of the Two Fishermen's Profits Exploiting Three Competing Species Where Prices Depend on Harvest
    The main purpose of this work is to define the fishing effort that maximizes the profit of each fisherman, but all of them have to respect two constraints: the first one is the sustainable...

    Keywords: FishingharvestNash equilibriumoptimizeprofits

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    2014-Wang-EtAl-Estimating Mixed-Effects Differential Equation Models
    When multiple replicates of measurements are available for the dynamic process, it is of great interest to estimate mixed-effects in the ODE model for the process. We propose a semiparametric...

    Keywords: pharmacokineticsdynamic modelssmoothingsplinemixed-effects modelsHiV combination therapy

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    2012-Nokkaew-EtAl-Estimation of Algae Growth Model Parameters by a Double Layer Genetic Algorithm
    This paper presents a double layer genetic algorithm (DLGA) to improve performance of the information-constrained parameter estimations.

    Keywords: optimizationalgae growthgenetic algorithmssimulated dataconvergence of parameters

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    2010-Brian_Winkel-Parameter estimates in differential equation models for chemical kinetics
    We discuss the need for devoting time in differential equations courses to modelling and the completion of the modelling process with efforts to estimate the parameters in the models using data.

    Keywords: kineticschemical kineticszeroth order reactionfirst order reactionsecond order reaction

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    2008-Ratneesh_Suri-Optimal harvesting strategies for fisheries-differential equations approach
    We develop and investigate the harvesting model in both deterministic and stochastic settings. We first employ the Expected Net Present Value approach and determine optimal harvesting policy using...

    Keywords: optimal controlsustainable yieldmaximum sustainable yieldharvestExpected Net Present Valuecalculus of variationsdynamic programmingmaximum economic yield

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    2008-Duran-Caginalp-Parameter optimization for differential equations in asset price forecasting
    The optimization procedure is used in conjunction with daily market prices (MPs) and net asset values to determine the parameters for which the AFDE yield the best fit for the previous n days.

    Keywords: financeinverse problemnumerical nonlinear optimizationasset flowfinancial market dynamicsmarket return prediction algorithm

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    2007-Mogen_Steffensen-Differential Equations in Finance and Life Insurance
    The mathematics of finance and the mathematics of life insurance were always intersecting. Life insurance contracts specify an exchange of streams of payments between the insurance company and the...

    Keywords: financedisabilitylife insurancemortalityinsuraneThiele’s equationBlack-Scholes equation

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    Engaging Students in Pharmacogenetics: Patient Case Studies Using the PharmGKB Website
    Cytochrome P450 (CYP) enzymes are important regulators of drug efficacy and toxicity. Genetic variation in CYP isoforms can impact how well patients respond to medications or experience unwanted...

    Keywords: toxicologyPharmacologydrug metabolismpharmacodynamicspharmacogenetics

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    2003-Knorrenschild-Gross-Text Books on Mathematical Modeling in Biology
    Text Books on Mathematical Modeling in Biology Compiled from the Internet by Michael Knorrenschild,

    Keywords: biologyMathematical Biologytextbooktext

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    2002-Chai-Optimal initial angle to fire a projectile
    Assume a projectile is fired without air resistance and lands at a height y above its initial vertical position. What is the optimal initial angle of firing to maximize the horizontal distance...

    Keywords: optimizationprojectile motionlaunch angle

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    2001-Knisley-Kerley-Using data to motivate the models used in introductory differential equations
    In this paper, the data itself is used to motivate mathematical models in introductory mathematics courses. In doing so, various regression and optimization techniques are illustrated.

    Keywords: regressionlogisticTorricelli's Lawgrowthperiodic process

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    1999-Khorasheh-Ahmadi-Gerayeli-Application of Direct Search Optimization for Pharmacokinetic Parameter Estimation
    For simple pharmacokinetic compartmental models, analytical solution to the governing differential equations provide a mean to evaluate the associated rate constants. Such methods, however, can not...

    Keywords: sum of square errorsleast squarespharmacokineticslineteicscompartmental modelsdirect search

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