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    Going Remote: An Online Adaptation to Using a Primary Cell Culture Model to Study the Neural Extracellular Matrix
    In light of the COVID-19 pandemic, instructors have modified materials to transition to a remote learning platform. The challenge for science instructors has been to design lab exercises that...

    Keywords: remote learningExtracellular matrixNeural extracellular matrixPerineuronal net

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    Chilling in the Cold: Using Thermal Acclimation to Demonstrate Phenotypic Plasticity in Animals
    The lesson plan described here provides students hands-on, scientific experiences that relate to the globally important issue of climate change and its impacts on animals. Students use the...

    Keywords: scientific methodclimate changephenotypic plasticityfruit fliesaccclimationcold tolerancethink-pair-share

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    Investigating Gene Expression and Cell Specialization in Axolotl Embryos
    The process of cell specialization is critical to the formation and function of tissues in animals and plants. Although gene expression, including the regulation of transcription, is taught in most...

    Keywords: developmenttranscriptiongene expressionmodel organismembryo

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    Vitamin C for Colds? Writing LETTERS to Synthesize and Communicate Results from Multiple Studies
    Interpreting experimental results is a key part of evidence-based reasoning. However, it is challenging for students to synthesize data from multiple sources to reach their own conclusions. As...

    Keywords: pre-healthphysiologyScience Communicationscientific literacyScientific Processconventional wisdomscientific methods

    2015

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    DNA Detective: Genotype to Phenotype. A Bioinformatics Workshop for Middle School to College.
    Advances in high-throughput techniques have resulted in a rising demand for scientists with basic bioinformatics skills as well as workshops and curricula that teach students bioinformatics...

    Keywords: geneticsbioinformaticsDNAgenotypephenotypegenegene annotation

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    A Short Laboratory Module to Help Infuse Metacognition during an Introductory Course-based Research Experience
    A core competency identified in Vision and Change for undergraduate biology students is the Ability to Apply the Process of Science. Here, we describe a three-week laboratory module for students in...

    Keywords: metacognitiongene expressionScientific ProcessExperimenal DesignHypothesis Generationmodel organisms

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    Mice, Acorns, and Lyme Disease: a Case Study to Teach the Ecology of Emerging Infectious Diseases.
    Ebola, Zika, the recall of contaminated lettuce - these are just a few recent outbreaks making headlines. Students should be able to connect what they learn in their biology courses to explain...

    Keywords: epidemiologyEcological changeInfectious disease ecologyReservoirsTransmission cycle

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    Discovering Prokaryotic Gene Regulation by Building and Investigating a Computational Model of the lac Operon
    The ability to construct and reason through a biological system is an important skill to develop in science education. This level of understanding forces students to recognize the interrelatedness...

    Keywords: prokaryotesgene regulationLac Operoninducible operon

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    A Close-Up Look at PCR
    The Polymerase Chain Reaction (PCR) is a fundamental laboratory technique that allows for the amplification of many copies of a desired DNA target sequence. Despite its prevalence, undergraduate...

    Keywords: PCRDNA replication

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    Linking Genotype to Phenotype: The Effect of a Mutation in Gibberellic Acid Production on Plant Germination
    Basic concepts in genetics and plant development are often taught in lecture courses without a lab component. This approach provides students with the content knowledge, but fails to make...

    Keywords: geneticsdevelopmentmutationgerminationplantmodel organismGenotype/PhenotypeHormoneSeed

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    Using computational molecular modeling software to demonstrate how DNA mutations cause phenotypes
    Students require a deep understanding of the central dogma before they can understand complex topics such as evolution and biochemical disorders. However, getting undergraduate biology students to...

    Keywords: Protein Structurecomputational modelingcentral dogmaplant leaf structurePhenotype/Genotype

    2002

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    The Case of the Missing Strawberries: RFLP analysis
    While solving the fictional mystery of the missing strawberries, students are engaged in a guided-inquiry lesson featuring small-group and class discussions, hands-on activities, and laboratory...

    Keywords: process of scienceDNAforensicsgel electrophoresisMolecular genotypingRestriction endonucleaseRestriction enzymeRestriction fragment length polymorphismRFLP

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    An Active Learning Workshop to Teach Active Learning Strategies
    College instructors who learn how to teach actively at the beginning of their careers do not have to modify deeply set habits that rely on lectures. Instead, they develop their teaching while they...

    Keywords: professional developmentActive-learning strategiesjigsawthink-pair-sharePedagogical approachesGallery WalkSmall group discussionInclusive practices

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    Fly Exercise: A Simple Experiment to Test the Physiological Effects of Exercise on a Model Organism
    Model organisms are commonly used to study and experimentally explore biological processes in ways that are technically or ethically not possible in humans. For this reason, model organisms are an...

    Keywords: exerciseenzyme kineticsmetabolite concentrationmodel speciesphysical activity

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    Sorry to Eat and Run: A Lesson Plan for Testing Trade-off in Squirrel Behavior Using Giving Up Densities (GUDs)
    All animals need to find and compete for food, shelter, and mates in order to survive and reproduce. They also need to avoid being eaten by predators. Optimal foraging theory provides a framework...

    Keywords: ecologyanimal behaviorAnimal form and functionAnimal nutritionSquirrel-Net

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    A CRISPR/Cas Guide RNA Design In Silico Activity
    CRISPR biotechnologies inspired by the Clustered Regularly Interspaced Short Palindromic Repeat RNA-guided nuclease adaptive bacterial immune system have revolutionized biology research and become...

    Keywords: bioinformaticsgene expressiongenetic basis of diseaseCRISPR/Cas9genetic engineeringin silico

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    Using Zebrafish in a Developmental Biology Lab Course to Explore Interactions Between Development and the Environment
    Important learning outcomes for biology students include the ability to develop experiments as well as pull together concepts across their coursework. The field of developmental biology, especially...

    Keywords: toxicologymorphogenesisorganogenesis

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    BioVEDA Curriculum: An Approach to Link Conceptual and Quantitative Understanding of Variation During Experimental Design and Data Analysis
    When performing a biological investigation, experts constantly cycle between conceptual and quantitative modes of thinking, integrating their understanding in both worlds to make decisions about...

    Keywords: statisticssample sizeBiological variation

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    Using Gamification to Teach Undergraduate Students about Scientific Writing
    Despite its importance, scientific writing is often deprioritized in undergraduate biology classes. Reasons include assumed prior knowledge, lack of class time, tedious grading, and the complexity...

    Keywords: gamificationscientific writingE-LearningInstant FeedbackInteractive LearningReading Scientific PapersVIdeo/computer game

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    Investigating Cell Signaling with Gene Expression Datasets
    Modern molecular biology is a data- and computationally-intensive field with few instructional resources for introducing undergraduate students to the requisite skills and techniques for analyzing...

    Keywords: genomicstranscriptionsignaling

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