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    2020-Stepien_Kostelich_Kuang-Mathematics Cancer An Undergraduate Bridge Course in Applied Mathematics
    Most undergraduates have limited experience with mathematical modeling. This paper describes a course on the mathematical models of cancer growth and treatment.

    Keywords: differential equationsmodelingundergraduate educationcancertumor

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    Go Extinct! An Award-Winning Evolution Game That Teaches Tree-Thinking as Students Pursue the Winning Strategy
    Evolutionary trees communicate both the diversity and unity of life, a central and important scientific concept, as highlighted by the Vision and Change undergraduate biology education movement....

    Keywords: phylogeneticsnatural historyBiodiversitycladogramCommon ancestorEvolutionary treeLand vertebratesMonophyletic cladeTetrapods

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    A Muscular Dystrophy Case Study Illustrating the Phenotypic Effects of Mutation
    Mutations in genes can lead to a variety of phenotypes, including various human diseases. Students often understand that a particular mutation in a single gene causes a disease phenotype, but it is...

    Keywords: mutationProtein Structureethicscentral dogmahuman disease

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    Isolation and Functional Analysis of a Pancreatic Enzyme in an Introductory Student Lab
    Structure and function are correlated at all levels of biology. This topic is typically addressed early in an undergraduate class in general or molecular biology before students have gained much...

    Keywords: Protein StructureproteaseEnzymechemical bondscatalysissolubility

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    Transitioning Two-Stage Exams to an Online Class
    Students often find biology courses to be very difficult and isolating, particularly if they identify as part of a group that has been historically excluded from STEM. Some of this anxiety and...

    Keywords: lower division STEMupper division STEM

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    Evolution of Tusklessness in African Elephants
    The exploitation of African elephants in the form of ivory poaching is exacerbated by warfare. The affects of this anthropogenic evolutionary force on the African savanna elephant (Loxodonta...

    Keywords: Hardy-Weinbergchi-squaredEvolutionExponentsRatiospercentselephantsGorongosa National ParkAfricaqbccUnderstanding fractionsSolving Equations and InequalitiesConcepts in Statisticsusing statisticstusk & tusklessIvory poachingFractions and Mixed NumbersDecimals

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    Application of a Bacterial Experimental Evolution System to Visualize and Teach Evolution in Action: A Course-Based Undergraduate Research Experience
    Concepts of evolution are typically taught through examples of extremely long timescales, which do not always resonate broadly. Here, we describe a course-based undergraduate research experience...

    Keywords: EvolutionmutationcompetitionNatural Selectionregulationstructure and functionreproductive fitnessgenotype to phenotypehomologs

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    9-001-SkinBurnModelNumericalMethods-TechniqueNarrative
    The heat equation is an important partial differential equation (PDE) which describes the distribution of heat in a given region over time. Numerical methods play an important role in solving these.

    Keywords: Maternal-Fetal interfaceheat equationConservation of Energytheat fluxEuler's forward methodcentral differenceskin burnhyperthermiathermal conductivitylayers

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    1-084-GoingViral-ModelingScenario
    Students employ randomization in order to create a simulation of the spread of a viral disease in a population (the classroom). Students then use qualitative analysis of the expected behavior of...

    Keywords: simulationlogisticrandomfittingpartial fractions

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    1-102-CancerTumor-ModelingScenario
    This module guides students in the use of differential equation models to predict cancer growth and optimize treatment outcomes. Several classical models for cancer growth are studied, including ...

    Keywords: optimizationlogisticpredictiondata fittingpower lawGompertzcancer growtheponentialBertalanaffy

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    4-065-GasInjection-ModelingScenario
    Students use programs (or create their own code) based on exponential box-scheme approximations for solving systems of nonlinear differential equations that contain small parameters for the highest...

    Keywords: Prandtl-Blasius equationsboundary layergas injectionesponential box schemeuniform convergenceFORTRAN

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    9-030-WaterHammer-ModelingScenario
    We develop and apply a numerical algorithm that solves a system of two nonlinear partial differential equations (PDEs) that describes the time evolution of the water hammer phenomenon.

    Keywords: Stock and Flow modelhyperbolic equationsfinite differenceswater hammerhydrodynamicscompressibilitywave celerity

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    9-010-TravelingWave-ModelingScenario
    Students are taken through a traveling wave analysis of a porous medium model. While the starting point is a nonlinear partial differential equation model, after a change of variables, students...

    Keywords: traveling wavesseepage velocityporous medium

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    9-005-InvasiveSpeciesModel-ModelingScenario
    This scenario takes students through the development of an invasive species partial differential equation model. Basic models are discussed first, which lead students to eventually develop their...

    Keywords: Invasive Specieslogisticmigrationtraveling wavesdispersion

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    9-012-PDEGuitarTuning-ModelingScenario
    We lead students through a derivation of a partial differential equation which models the motion of a string held at both ends, a case of the one-dimensional wave equation, and then play it on...

    Keywords: extensionsine wavesfrequencyguitardampingFourierstringtuning

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    Electron Location, Location, Location: Understanding Biological Interactions
    Introductory Biology courses typically introduce the structure and function of biomolecules such as proteins and nucleic acids. To understand biomolecules fully, students require knowledge of...

    Keywords: hydrogen bondshydrophobicity/hydrophilicitypolar and non-polar covalent bonds

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    From Dirt to Streptomyces DNA
    The purpose of this semester-long Lesson is to give students an authentic, course-based undergraduate research experience during which they learn basic and advanced microbiological and molecular...

    Keywords: MetabolismAntibiotic productionrRNA genesSecondary metabolitesStreptomyces

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    A Remote-Learning Framework for Student Research Projects: Using Datasets to Teach Experimental Design, Data Analysis and Science Communication
    Remote learning often requires an alternative to hands-on, student-designed research projects. To this end, we created a package of scaffolded assignments to support introductory students through...

    Keywords: population growthphysiologyecotoxicologyphotosynthesis

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    A CURE for Salmonella: A Laboratory Course in Pathogen Microbiology and Genomics
    Rapid advances in genomics and bioinformatics, the vast amount of data generated by next-generation sequencing, and the penetration of the ‘-omics’ into many areas of biology have created a need...

    Keywords: epidemiologyresearchbioinformaticsgenomicspublic healthAntibiotic Resistant BacteriaSalmonellaDNA sequencingpathogenic bacteria

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    Generating Biological Hypotheses in a "Course-based Undergraduate Research Experience"(CURE) Course
    Hypotheses are often incorrectly defined as educated guesses or if/then statements. Further confusion arises from the fact that not all disciplines define hypotheses similarly. The difficulty in...

    Keywords: scientific methodHPT axisNeural stem cells

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