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    A CRISPR/Cas Guide RNA Design In Silico Activity
    CRISPR biotechnologies inspired by the Clustered Regularly Interspaced Short Palindromic Repeat RNA-guided nuclease adaptive bacterial immune system have revolutionized biology research and become...

    Keywords: bioinformaticsgene expressiongenetic basis of diseaseCRISPR/Cas9genetic engineeringin silico

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    Modeling the Research Process: Authentic human physiology research in a large non-majors course
    Laboratory experiences in large-enrollment introductory science courses often utilize “cookie-cutter style” laboratory experiences due to the relative simplicity of setting up the lab...

    Keywords: data analysishypothesis testingexperimental designphysiology

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    Using Bioinformatics and Molecular Visualization to Develop Student Hypotheses in a Malate Dehydrogenase Oriented CURE
    Developing student creativity and ability to develop a testable hypothesis represents a significant challenge in most laboratory courses. This lesson demonstrates how students use facets of...

    Keywords: bioinformaticsNoncovalent InteractionsEnzyme CatalysisProtein Structure/function

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    6-008-PursuitModels-Modeling Scenario
    Students are prompted to build systems of nonlinear differential equations to model pursuit-evader activities in which a pursuer attempts to follow, perhaps track down and come close to, an evader...
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    Follow the Sulfur: Using Yeast Mutants to Study a Metabolic Pathway
    Students are frequently overwhelmed by the complexity of metabolic pathways and they think they have "learned" the pathway when they have memorized the individual reactions.  This...

    Keywords: SelectionyeastMetabolismcysteinemediamethioninemutantPathwaysulfur

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    Implementing an online module on microbe-plant interactions in the context of ecological disturbance for Microbiology and Biochemistry courses in India
    This module explores tropical forest gap dynamics and helps students develop hypotheses about climate-related changes in plant-microbial interactions and was implemented in Microbiology and...

    Keywords: data analysisscientific methoddata interpretationdisturbance ecologyexperiential learningCarbon sequestration in tropical rainforestPlant Microbial interactionsCanopy GapUndergraduate MicrobiologyNational Education Policy 2020

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    2014-Hrydziuszko-EtAl-Mathematical Two-compartment Model of Human Cholesterol Transport
    We develop a two-compartment mathematical model to investigate cholesterol transport in the circulatory system and its de novo synthesis in the liver.

    Keywords: metabolic syndromecompartmentcholesteroltwo-compartment modelcholesterol transport

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    2011-Lucas_Pulley-Analyzing Predator-Prey Models Using Systems of Ordinary Linear Differential Equations
    This research focused on applying biological mathematics to analyzing predation relationships, especially the relationship between the Canadian Lynx and the Snowshoe Hare.

    Keywords: simulationpredator-preyLotka-VolterrapopulationCanadian LynxSnowshoe Harecritical values

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    Distances in the Universe: An Inquiry Lab Sequence Taught in West Africa and North America
    Astronomy evokes deep curiosity for many people, making it a beautiful topic for supporting students to learn scientific practices and develop as scientists. We present an inquiry-based lab...

    Keywords: InquiryAstronomy labParallaxInverse-square law for lightCosmic distance ladderAsking investigable questions

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    Your Tax Dollars at Work: A mock grant writing experience centered on scientific process skills
    A successful scientist combines skill, creativity, and the art of persuasion to excel in his or her field of study. Critically important for the professional scientist is the ability to not only...

    Keywords: researchexperimental designprocess of sciencePeer reviewgrant writingPecha Kuchaproposal

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    Exploring the City of Biofilms: An Engaging Analogy-Based Activity for Students to Learn Biofilms
    Multicellular biofilms constructed by microbes are key aspects of microbiology with significant implications in various fields, including medicine, environmental science, and biotechnology. While...

    Keywords: bacteriaBiofilmsquorum sensing

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    A Short Laboratory Module to Help Infuse Metacognition during an Introductory Course-based Research Experience
    A core competency identified in Vision and Change for undergraduate biology students is the Ability to Apply the Process of Science. Here, we describe a three-week laboratory module for students in...

    Keywords: metacognitiongene expressionScientific ProcessExperimenal DesignHypothesis Generationmodel organisms

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    7-010-MultipleDoses-ModelingScenario
    Two multiple dose drug administration regimens are offered. A drug is to maintain a certain level (above a set minimum and below a set maximum) in the blood stream and one regimen involves bolus...

    Keywords: drug discoverystep functiondoseDiracdrug administrationinverse Laplace Transformintraveneousbolussteady drip

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    Globally endangered sea turtles of the Palmyra Atoll National Wildlife Refuge: A Focus on Scientific Analysis
    Based on the sea turtle case, students will (1) work on a worksheet by analyzing existing survey data, (2) conduct a literature review of two relevant research, and (3) draft a proposal for a...

    Keywords: sea turtle conservationliterature reviewResearch methodsProposal writingPalmyra Atoll

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    Investigating Enzyme Structure and Function Through Model-Building and Peer Teaching in an Introductory Biology Course
    A foundational knowledge of the relationship between structure and function is critical to understanding how enzymes work. The seemingly invisible nature of these molecular interactions makes it...

    Keywords: structure-functionEnzymeallosteric regulationcompetitive inhibitionfeedback inhibitionnoncompetitive inhibitionproductsubstrate

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    My Fish Tank: An Active Learning Activity for Bacterial Nitrogen Metabolism
    This active learning activity introduces students to the second part of the nitrogen cycle, nitrification. In terrestrial and aquatic environments, bacteria from the Nitrosomonas and Nitrobacter...

    Keywords: nitrogen cyclenitrificationnitrifying bacteria

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    Using Seafood Traceability to Teach the Complexities of Natural Resource Management and Sustainability
    This lesson plan addresses the challenge of conveying to students the globalized nature and complexity of natural resource management. Specifically, it uses seafood traceability, or the ability to...

    Keywords: sustainabilityfisheriesaquacultureAnthropogenic ImpactsNatural Resource Management

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    Implementing an online module about impacts of pollution from gold mining in an undergraduate ecology course in the Pacific Northwest, USA
    Students learn about biomagnification of toxins, build skills in graphical interpretation, and apply field methods to tackle complex issues about small-scale gold mining in the Peruvian Amazon....

    Keywords: food websmercury biogeochemistryBioaccumulationbiomagnificationPeruvian Amazon

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    The Undergraduate Student’s Guide to Geometric Morphometrics
    Embarking on a new research endeavor can be a daunting task. User guides, books, and published articles are written for an audience that already has some background experience in the field....

    Keywords: researchGeometric Morphometrics"body shape""shape analysis"

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    2008-Abramson-Mathematical modeling of the spread of infectious diseases
    These are informal notes, mostly based on the bibliography listed at the end and on recent papers in the field. The practical use of these models is based on the fact that they can be kept...

    Keywords: infectious diseasebibliographyepidemiccowpoxsmallpoxcomplex networksspread disease

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