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    Chilling in the Cold: Using Thermal Acclimation to Demonstrate Phenotypic Plasticity in Animals
    The lesson plan described here provides students hands-on, scientific experiences that relate to the globally important issue of climate change and its impacts on animals. Students use the...

    Keywords: scientific methodclimate changephenotypic plasticityfruit fliesaccclimationcold tolerancethink-pair-share

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    The Great Petunia Carnage of 2017: A Clicker Case Study Using Petunias to Describe the Effect of Genetic Modification on the Biochemistry of Flower Color and Phenotype in Plants
    In this single class period case study, students examine the difference between genotype and phenotype by studying the mechanisms by which commercially available petunias have been bred to have...

    Keywords: case studyGenetic ModificationsBiochemistry of Flower ColorGMO regulationsGenotype-Phenotype Connections

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    What is Speciation, How Does It Occur, and Why Is It Important for Conservation?
    Speciation provides a framework for classifying biodiversity on Earth and is a central concept in evolutionary biology. To help undergraduate students learn about speciation, we designed a...

    Keywords: EvolutionconservationGenetic DriftSpeciationNatural SelectionBiological species conceptgene flowMorphological species conceptPhylogenetic species concept

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    Splicing it Together: Using Primary Data to Explore RNA Splicing and Gene Expression in Large-Lecture Introductory Biology
    At the heart of scientific ways of knowing is the systematic collection and analysis of data, which is then used to propose an explanation of how the world works. In this two-day module, students...

    Keywords: gene regulationtranscriptiongene expressioncentral dogmarepressoralternative splicingmRNA processingActivatorTranscription factors

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    Building a Model of Tumorigenesis: A small group activity for a cancer biology/cell biology course
    The multistep nature of tumorigenesis is a foundational concept in the context of Cancer Biology. Many students do not appreciate the complex nature of cancer development nor do they understand how...

    Keywords: pathwayscancerMolecular AlterationsRetrospective dataTumorigenesis

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    Visual Glossary Of Insect Morphology
    A visual glossary of insect morphology created for undergraduate students and those new to insect identification. A description and visualization is provided for key features and terminology needed...

    Keywords: morphologyguideentomologyinsectsBLUEpollinators

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    5-030-LinNonHomoSystemSol-TechniqueNarrative
    We offer strategies for solving linear systems of nonhomogeneous differential equations using a conjectured solution strategy for a system of constant coefficient, linear, n

    Keywords: strategiesdiscovery learningeigenvectorseigenvalue

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    Coloring and Keying Great Lakes Trees
    In this set of activities, you will use the Michigan Trees Coloring book to learn and practice plant identification. You will also simulate some of the steps of specimen preparation by keying an d...

    Keywords: BiodiversitytaxonomyHerbarianatural history education

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    Population Bottlenecks: Heterozygosity vs. Allelic Diversity
    This module introduces heterozygosity and allelic diversity in the context of understanding population bottlenecks. It is intended for an introductory biology audience.

    Keywords: Ratiosexponential equationsAlgebraGenetics and Evolution

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    Transpiration
    In this lab, students will examine differences between varieties of tomato plants in their transpiration rates.

    Keywords: plant physiologybotanylaboratoryResource Typetranspirationtomatofood security

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    Allele and Phenotype Frequencies in Rock Pocket Mouse Populations
    A lesson that uses real rock pocket mouse data collected by Dr. Michael Nachman and his colleagues to illustrate the Hardy-Weinberg principle.

    Keywords: EvolutionResources @ HHMI - BioInteractiveNatural SelectionScientific ProcessStatistics and Mathevolution of populations

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    Using computational molecular modeling software to demonstrate how DNA mutations cause phenotypes
    Students require a deep understanding of the central dogma before they can understand complex topics such as evolution and biochemical disorders. However, getting undergraduate biology students to...

    Keywords: Protein Structurecomputational modelingcentral dogmaplant leaf structurePhenotype/Genotype

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    Predicting and classifying effects of insertion and deletion mutations on protein coding regions
    Mutations in genes can affect the encoded proteins in multiple ways, and some of these effects are counterintuitive. As for any other knowledge, students must create their own deep understanding of...

    Keywords: mutationcentral dogmatranslationframeshift

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    HITS: A network to create inquiry-based case studies that make high-throughput approaches and discovery accessible
    Poster on the work of the NSF-funded High-throughput Discovery Science & Inquiry-based Case Studies for Today’s Students (HITS) Research Coordination Network. Presented at the 2021 BIOME Institute.

    Keywords: case studieshigh-throughputHITSHigh-throughput Discovery Science & Inquiry-based Case Studies for Today’s Students2021 BIOME

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    Targeting Misconceptions in the Central Dogma by Examining Viral Infection
    Understanding the central dogma and how changes in gene expression can impact cell function requires integration of several topics in molecular biology. Students often do not make the necessary...

    Keywords: datatranscriptionvirustranslationprotein functionmembrane transportPredictions

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    Science Behind the Lesson: It's a Bird! It's a Plane! It's Biomechanics!
    Active flight is a specialized mode of movement found in insects, birds, and mammals. The anatomy, morphology, physiology, and ecology of flying taxa has changed over evolutionary time. Researchers...

    Keywords: EvolutionecologybatphysiologyAnatomybiomechanicsbirdFlightinsect

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    DNA Detective: Genotype to Phenotype. A Bioinformatics Workshop for Middle School to College.
    Advances in high-throughput techniques have resulted in a rising demand for scientists with basic bioinformatics skills as well as workshops and curricula that teach students bioinformatics...

    Keywords: geneticsbioinformaticsDNAgenotypephenotypegenegene annotation

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    A Rapid Genetic Screen Using Wisconsin Fast Plants®: A Hands-On Approach to Inheritance of de novo Mutations
    Some concepts in genetics, such as genetic screens, are complex for students to visualize in a classroom and can be cumbersome to undertake in the laboratory. Typically, very large populations are...

    Keywords: mutationInheritancegermlinesomaplant lifecycle

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    Learn Biological Sciences and Environmental Science through biodiversity and pollution
    Biodiversity or biological diversity is the variety of and variability of biological life on Earth. Biodiversity is existing due to variation among living organisms from different sources air,...

    Keywords: databiologydata scienceBiodiversityclimateenvironmental scienceSpeciespollutionanalyze data

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    7-020-ThermometerInVaryingTempStream-ModelingScenario
    We present a first order differential equation model for the temperature of a mercury thermometer which is sitting in a stream of water whose temperature oscillates. We suggest a solving strategy...

    Keywords: temperaturesteady statethermometerheat exchangetransfer functionphase lagInvers Laplace Transform

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