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    The Leaky Neuron: Understanding synaptic integration using an analogy involving leaky cups
    Students have difficulty understanding synaptic integration in neural circuits, and how spatial and temporal summation combine in a target neuron to reach threshold.  This Lesson uses small...

    Keywords: neuron physiologyspatial summationsynaptic integrationtemporal summationthreshold

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    Using a Sequential Interpretation of Data in Envelopes (SIDE) approach to identify a mystery TRP channel
    This lesson sought to engage students in data interpretation and to encourage critical thinking about neurophysiology in the context of temperature sensation. A family of receptors called Transient...

    Keywords: Cell communicationChannel specificity and activationLimitations of tools of Cell BiologyNeuronal Signaling

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    Investigating the Function of a Transport Protein: Where is ABCB6 Located in Human Cells?
    One of the challenges of teaching Cell Biology is helping students understand important research methods used to study cells.  The goal of understanding cell biology methods is especially...

    Keywords: ABC transporter familyDifferential centrifugationImmunoblottingImmunofluorescence assayProtein localizationPurifying organellesSDS-PAGE

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    Evaluating the Quick Fix: Weight Loss Drugs and Cellular Respiration
    One key to student success in introductory and cell biology courses is a foundational knowledge of cellular respiration. This is a content area in which students often harbor misconceptions that...

    Keywords: data analysisCellular RespirationElectron Transport ChainEnergy transformationsMitochondriaOxidative phosphorylationWeight loss drugs24-dinitrophenol (DNP)

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    A simple way for students to visualize cellular respiration: adapting the board game MousetrapTM to model complexity
    Lecture-based introductory biology courses are typically content-heavy as instructors strive to provide students with foundational knowledge in a broad range of topics.  One topic...

    Keywords: ATPGlycolysisCellular RespirationElectron Transport ChainKrebs Cycle

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    Meiosis: A Play in Three Acts, Starring DNA Sequence
    Meiosis is well known for being a sticky topic that appears repeatedly in biology curricula. We observe that a typical undergraduate biology major cannot correctly identify haploid and diploid...

    Keywords: recombinationmeiosisDNA sequenceCrossingoverchromosome structureHolliday junctionhomology

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    Grow the Gradient: An interactive countercurrent multiplier game
    The countercurrent multiplier of the loop of Henle in a mammalian kidney is a challenging concept for instructors to teach and for students to learn. We developed an interactive game to support...

    Keywords: countercurrent multiplierexcretory systemkidneyloop of Henlemembrane transport

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    Inexpensive Cell Migration Inquiry Lab using Zebrafish
    Cell migration is an important and interesting topic that has the potential to engage students in cell biology by its intrinsically active nature. However, most ways to investigate cell migration...

    Keywords: CytoskeletonCell migrationmodel organisms

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    Taking the Hassle out of Hasselbalch
    Mention pH in a classroom and you can almost see the inner yawn on the faces of your students. The definition may even roll easily from their lips. However, despite multiple exposures to the...

    Keywords: pHdrug uptakeHenderson-Hasslbalch equationmedical applicationspKa

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    Lights, Camera, Acting Transport! Using role-play to teach membrane transport
    Lights, Camera, Acting Transport! is an active and unique role-play exercise designed to teach introductory biology students basic concepts of passive and active membrane transport. The activity...

    Keywords: ATPcarrierschannelsco-transportelectrogenic pumpfacilitated diffusionmembrane transportpassive transportprimary active transportsimple diffusion

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    Modeling the lac Operon to Understand the Regulation of Gene Expression in Prokaryotes
    This resource is a recitation activity designed for an introductory biology course in which students explore a lac operon simulation (https://qubeshub.org/resources/phetlacoperon).

    Keywords: simulationLac Operon

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    Chemoreception
    This module introduces the probability of cell and molecule collisions in the context of understanding chemoreception. It is intended for an introductory biology audience.

    Keywords: linear equationshyperbolic equationsCellular ProcessesChemoreception

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    Diffusion Through a Cell Membrane
    This module introduces rates of diffusion in the context of understanding simple and facilitated diffusion through the cell membrane. It is intended for an introductory biology audience.

    Keywords: linear equationscalculushyperbolic equationsCellular Processesrates of change

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    Nuclear and Cytoplasmic Viscosity
    This module introduces a modified Stokes-Einstein equation in the context of understanding the difference in viscosity between the nucleus and cytoplasm of cells

    Keywords: linear equationsCell StructureCell GrowthCytoplasmic Viscosity

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    Nucleo-cytoplasmic Transport
    This module introduces exponential decay and the rate of influx in the context of understanding the transport of molecules from the cytoplasm to the nucleus. It is intended for an introductory...

    Keywords: exponential equationsCell StructureCell Growth

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    Quantitative Cytological Characteristics: Photorespiration
    This module introduces quantitative cytological characteristics in the context of understanding cell behavior under stress. It is intended for an introductory biology audience.

    Keywords: plant physiologyRatioschart

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    Synapse Transmission and Action Potentials
    This module introduces action potentials in the context of understanding nerve impulses. It is intended for an introductory biology audience.

    Keywords: InequalitiesOpenStaxAnimal Physiology

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    Water Movement through a Membrane: The Van't Hoff Equation
    This module introduces the van't Hoff equation in the context of understanding the metabolic activity of the epithelial cells lining the stomach. It is intended for an introductory biology audience.

    Keywords: AlgebraInequalitiesCellular Processes

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    Permeability of Molecules
    This module introduces Overton's Rule in the context of understanding the permeability of molecules across the cell membrane. It is intended for an introductory biology audience.

    Keywords: linear regressionPermeabilityCell StructureCell MembraneOpenStaxphospholipid membranelog-log plotsOverton's rule

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    Fitzhugh-Nagumo Model
    The FitzHugh–Nagumo model describes a prototype of an excitable system (e.g., a neuron).

    Keywords: differential equationsmathematical modeldifferential equation modelordinary differential equation modelneuroscienceexcitable

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