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The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

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    Drugging SARS-CoV-2
    This case study leads students through the process of proposing a drug for a novel protein. The Mpro protease of SARS-CoV-2 is explored in detail within the PDB. Aligns with first semester...

    Keywords: viruscoronavirusPDBSARS-CoV-2proteasedrug design

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    Introduction to Genome Annotation
    This exercise is an adaptation of the Annotation Lesson by Rosenwald et al. It introduces the use of bioinformatics tools to extract information from genome databases. It is a basic lesson on...

    Keywords: microbiologyGenome annotationBioinformatics EducationBioinformatics and Genomics

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    Soil Respiration Module (Project EDDIE)
    Soils hold more carbon (C) than any other component of the terrestrial biosphere!

    Keywords: Project EDDIE

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    Stream Discharge Module (Project EDDIE)
    Stream discharge is a fundamental measure of water supply in stream systems. Low discharge may cause problems with water supply and fish passage, while high discharge may mean flooding. In this...

    Keywords: floodsProject EDDIEurbanizationstreams

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    The p53 Gene and Cancer
    This tutorial describes the structure and function of the p53 protein, how its activity is regulated in cells, and how mutant versions of p53 can lead to cancer.

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymolecular biologymacromoleculesGenetic disease

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    Adaptation of Investigating human impacts on stream ecology: locally and nationally
    TIEE Module- How does nutrient pollution impact stream ecosystems locally and nationally?
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    Adaptation of Terrestrial Trophic Cascades & Population Structure to a Non-Major’s Ecology Course
    In this activity, students will use data from natural parks to examine trophic cascades.

    Keywords: case studyBiodiversityplantsResource Typetrophic cascadesnational parks

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    Calculus, Zombies, Community, and QUBES
    Presentation discussing approaches to determining the content and delivery structure for quantitative integration into the curriculum of foundational courses in both statistics and calculus for the...

    Keywords: math bio edzombiesmath confidenceumaine

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    SEAS CURE: Exploring Coral Biology Across Scales
    Complex biological concepts (like symbiosis and coral biology) that span multiple scales and cross disciplinary boundaries are often difficult for students to understand. This complexity is...

    Keywords: microscopyAnatomySymbiosisMetabolismbleachinginvertebratedinoflagellate

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    COVID-19: Molecular Basis of Infection-ADAPTATION
    This case was written in Spring 2020 during the COVID-19 pandemic. It focuses on understanding the structure and interaction of the SARS-Cov-2 viral spike protein that facilitates infection in...

    Keywords: infectionvaccinemolecular visualization and analysisCOVID19PDBSARS-CoVMolecular Case Study

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    Introduction to Plant Phenology with Museum Specimens of Desert Prickly Pear (Opuntia phaeacantha)
    Students engage in hands-on exploration of phenology by working with digitized herbarium specimens, particularly focusing on prickly pear specimens from the UTEP herbarium. They learn to identify...

    Keywords: botanyclimate changephenologyherbariumcactus

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    Conserving Water in a Time of Climate Change: What are the Benefits of Using Greywater on Household Gardens
    We were curious if there would be any simple way to decrease water use in communities because of the ongoing drought in California. To do this, we would use three different types of greywater,...

    Keywords: conservationclimate changewater resources

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    The Evolution (and Coevolution) of Flowering Plants Virtual Classroom
    In this lab, you will explore the diversity of flower and fruit adaptations that have evolved to accomplish pollination and seed dispersal and you will investigate the coevolution of angiosperms...

    Keywords: digital resourcespollination biologynatural history collectionsFloral Diversity

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    Joel E. Greengiant Learns About Peas: From Nucleotides to Selection
    This case study follows purveyors of peas, Joel E. and Jolene Greengiant, as they learn about the origin, biochemistry, genetics and eventual artificial selection of sweet (wrinkled) peas, all in...

    Keywords: geneticspopulation geneticsEvolutionintroductory biologycase studybiologyResources @ NSF - NCCSTSmeiosisMendel’s peaspea plantPisum sativumMendel’s Lawsmolecular geneticsmutationnucleotide insertionartificial selectionstarch synthesisstarch branching enzymeplant domesticationlegumesResources @ QUBES - Teaching & Reference

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    The Biology of Climate Change: The effects of a changing climate on migrating and over-wintering species at a high-elevation field station
    Students evaluate weather and phenology data sets spanning 40+ years from a high-elevation field station in the Colorado Rocky Mountains, to test predictions about the effects of climate change on...

    Keywords: species interactionsclimate changefmnphenologyDIGenvironmental variationtrophic mismatch

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    Investigating Enzyme Structure and Function Through Model-Building and Peer Teaching in an Introductory Biology Course
    A foundational knowledge of the relationship between structure and function is critical to understanding how enzymes work. The seemingly invisible nature of these molecular interactions makes it...

    Keywords: structure-functionEnzymeallosteric regulationcompetitive inhibitionfeedback inhibitionnoncompetitive inhibitionproductsubstrate

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    Analyzing interesting images motivates mathematics and statistics learning
    Presentation by Jeremy Wojdak made as part of the "Bringing Research Data to the Ecology Classroom: Opportunities, Barriers, and Next Steps” Session at the Ecological Society of America annual...

    Keywords: Ecological Society of America

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    A Customizable Inquiry-Based Statistics Teaching Application for Introductory Biology Students
    Building strong quantitative skills prepares undergraduate biology students for successful careers in science and medicine. While math and statistics anxiety can negatively impact student learning...

    Keywords: introductory biologyQuantitative reasoningInclusive teachingauthentic inquiryInferential statisticsInstructional scaffolding

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    Making Change Sustainable: Network for Integrating Bioinformatics into Life Sciences Education (NIBLSE) Meeting Review
    The purpose of the meeting described in this review was to decide how best to ensure the sustainability of the Network for Integrating Bioinformatics into Life Science Education (NIBLSE; pronounced...

    Keywords: meetingsustainabilityfmnNIBLSEincubator

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    Tackling "Big Data" with Biology Undergrads: A Simple RNA-seq Data Analysis Tutorial Using Galaxy
    Analyzing high-throughput DNA sequence data is a fundamental skill in modern biology. However, real and perceived barriers such as massive file sizes, substantial computational requirements, and...

    Keywords: bioinformaticsDNA sequenceRNAseqgene expression

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