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    Electron Location, Location, Location: Understanding Biological Interactions
    Introductory Biology courses typically introduce the structure and function of biomolecules such as proteins and nucleic acids. To understand biomolecules fully, students require knowledge of...

    Keywords: hydrogen bondshydrophobicity/hydrophilicitypolar and non-polar covalent bonds

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    A Simple Method for Predicting a Molecule's Biological Properties From Its Polarity
    The distinction between very polar and less polar substances is a foundation of biochemistry, cell biology, and physiology; it surfaces in multiple concept inventories and elaborations of...

    Keywords: Diffusionsolubilitycovalent bondshydrophilichydrophobicpartition coefficientplasma membranepolarity

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    Cleaning Biodiversity Data: Excel
    Access and clean an open source polar bear dataset using Excel.

    Keywords: data in the classroombiodiversity informaticsData cleaning

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    Macromolecular math
    This worksheet was developed for use in an introductory biology course to review the chemical bonds and structure of biological macromolecules. A nutritional label is provided to illustrate that...

    Keywords: introductory biologycarbohydratesProtein StructureNucleic Acid Structuremacromoleculesnon-covalent interactionpolypeptidechemical bonds

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    The Polar Bear of the Salt Marsh?
    National Center for Case Study Teaching in Science- in this interrupted case study, students follow a young naturalist as she explores why saltmarsh sparrows are increasingly rare in coastal...

    Keywords: Coastal wetlandsConnecticutmanagementnortheastsea-level risesalt marsh

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    Global Temperature Change in the 21st Century: An Introduction to Global Climate Models and Graphing in Excel (Adapted for Non-Majors)
    Students link human behavior in various climate change scenarios to predicted temperature outcomes at both local (their assigned Latitude) and global (Latitudinal trends) scales. This adaptation is...

    Keywords: ExcelResources @ ESA - TIEEecology labclimate changeenvironmental scienceglobal changehuman-environmental interactionsSimple Linear Regressionhuman impactsinclusive pedagogy-FMN

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    The Polar Bear of the Salt Marsh? Warming Tolerance Limits of Local Species
    National Center for Case Study Teaching in Science- In the adaptation exercise, students explore connections between saltmarsh sparrow declines and declining populations of local species that live...

    Keywords: Coastal wetlandsConnecticutmanagementnortheastsea-level risesalt marsh

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    Serotonin in the Pocket: Non-covalent interactions and neurotransmitter binding
    This lesson introduces beginning biochemistry students to the concept of a biomolecule binding site, such as a neurotransmitter receptor site or an enzyme active site. A simple organic molecule,...

    Keywords: active sitebindingbinding sitehydrogen bondinghydrophobic effectionic interactionsnon-covalent forces

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    1-053-SlimeSpread-ModelingScenario
    We offer a video showing real time spread of a cylinder of slime and challenge students to build a mathematical model for this phenomenon.

    Keywords: spreadsheetsslime

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    1972-Suresh_Sethi-Optimal Control of the Vidale-Wolfe Advertising Model
    This paper considers an optimal-control problem for the dynamics of the Vidale-Wolfe advertising model, the optimal control being the rate of advertising expenditure to achieve a terminal market...

    Keywords: Optimal Control Theoryadvertisingsales

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    Gibb’s Free Energy and the Nature of Chemical Reactions
    This module introduces Gibb’s Free Energy in the context of understanding the nature of chemical reactions. It is intended for an introductory biology audience.

    Keywords: ExponentsLogarithmsRatiosexponential equationsSequencesCell StructureOpenStaxCell Growthgeometric equations

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    Lizard cold tolerance and extreme weather events: a scientist spotlight featuring Dr. Shane Campbell-Staton
    Students interpret experimental and observational data about patterns in cold tolerance in the green anole. They reflect on the experience and identity of the lead researcher based on a video...

    Keywords: climate changeNatural Selectionenvironmental variationphenotypic plasticityacclimationenvironmental conditions

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    Using Open-Source Bioinformatics and Visualization Tools to Explore the Structure and Function of SARS-CoV-2 Spike Protein
    The relationship between protein structure and function is a foundational concept in undergraduate biochemistry. We find this theme is best presented with assignments that encourage exploration and...

    Keywords: bioinformaticsmolecular modelingCOVID19protein structure and functionUCSF ChimeraSARS-CoV-2 spike proteinACE2 receptor

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    The Science Behind Parthenogenesis: Interesting things happen when meiosis goes “wrong”
    Parthenogenetic reproduction is a fascinating, complex topic.  This article accompanies “Why Meiosis Matters: The case of the fatherless snake.” It summarizes the basic information...

    Keywords: meiosismitosissex determinationAsexual reproductionParthenogenesis

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    A Muscular Dystrophy Case Study Illustrating the Phenotypic Effects of Mutation
    Mutations in genes can lead to a variety of phenotypes, including various human diseases. Students often understand that a particular mutation in a single gene causes a disease phenotype, but it is...

    Keywords: mutationProtein Structureethicscentral dogmahuman disease

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    An Interactive Protocol for In-Classroom DNA Extraction
    Using commonly available materials, this tool allows students to extract DNA, exploring DNA chemistry and the principles of experimental design and execution. We take a “Choose Your Own...

    Keywords: geneticsDNAbiochemical structure and function

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    A Close-Up Look at PCR
    The Polymerase Chain Reaction (PCR) is a fundamental laboratory technique that allows for the amplification of many copies of a desired DNA target sequence. Despite its prevalence, undergraduate...

    Keywords: PCRDNA replication

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    It's a Substrate... It's a Protein...No - It's an Enzyme! Teaching Using 3D Serine Protease Physical Modeling Activities to Confront Misconceptions.
    Reported misconceptions of enzyme-substrate interactions highlight the necessity for better, targeted instructional tools and assessments. A series of active learning activities with corresponding...

    Keywords: Protein StructureEnzymes-Substrate InteractionsNoncovalent InteractionsGeometric ComplementaryElectronicsStereochemistrySerine Proteases

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    Is Earth Currently Undergoing a Sixth Mass Extinction?
    The five Phanerozoic mass extinctions were central in shaping biodiversity on Earth today. Due to increasing biodiversity losses, there is debate about whether we are currently undergoing a sixth...

    Keywords: conservationBiodiversityextinctionMass ExtinctionDeep Time

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    Population Ecology of the Northern Spotted Owl
    The mathematical modeling of populations utilizing field-collected demographic data is an important component of lab curricula in a variety of undergraduate biology lab courses. During the global...

    Keywords: demographyCommunity Ecologypopulation ecologyconservation biologylife tables

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