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    Exploration of the Human Genome by Investigation of Personalized SNPs
    Students often shy away from tedious bioinformatics approaches to exploring their genomes. However, in our expanding digital world these skills are some of the most relevant and valuable. To...

    Keywords: UCSC genome browsersingle nucleotide polymorphismGenome wide association studiesGenomic organization

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    Translating Co-Translational Translocation
    Understanding the process of proteins targeting to specific locations within a cell is a fundamental part of cell biology. Synthesis of proteins by co-translational translocation, which also...

    Keywords: Topologyco-translational translocationendoplasmic reticulumprotease protection assaysecretory proteinssignal sequencetransmembrane proteins

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    Targeting Misconceptions in the Central Dogma by Examining Viral Infection
    Understanding the central dogma and how changes in gene expression can impact cell function requires integration of several topics in molecular biology. Students often do not make the necessary...

    Keywords: datatranscriptionvirustranslationprotein functionmembrane transportPredictions

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    Building a Model of Tumorigenesis: A small group activity for a cancer biology/cell biology course
    The multistep nature of tumorigenesis is a foundational concept in the context of Cancer Biology. Many students do not appreciate the complex nature of cancer development nor do they understand how...

    Keywords: pathwayscancerMolecular AlterationsRetrospective dataTumorigenesis

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    3-100-Ripcord-Toys-ModelingScenario
    This modeling scenario examines the motion of a ripcord-powered toy with the goal of using real data to estimate parameters in a first-order model of the velocity of the toy. Students may conduct...

    Keywords: dataphysicsdynamicsdata collectionrollingslippingripcordtoy

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    2015-Valerie_Billard-Pharmacokinetic-pharmacodynamic relationship of anesthetic drugs - from modeling to clinical use
    The purpose of this short review is to describe the basis of pharmacokinetics and modeling, the concentration-effects relationship, and drug interactions modeling to offer to anesthesiologists and...

    Keywords: anesthesiapharmacokineticspharmacodynamicanesthetic

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    2007-Choisy-Guégan-Rohani-Mathematical Modeling of Infectious Diseases Dynamics
    After presenting general notions of mathematical modeling (Section 22.2) and the nature of epidemiological data available to the modeler (Section 22.3), we detail the very basic SIR epidemiological...

    Keywords: stochasticSIR modeldeterministicincubationinfectives

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    Discrete Math Modeling with Biological Applications (Course Materials)
    These are the materials for Math 214 offered at Rhodes College.

    Keywords: labsagent-based modelingDiscrete Difference Equationsmatrix modelscoursebiomath coursedemonstrationin-class activitylab protocolproblem set

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    Does Organelle Shape Matter?: Exploring Patterns in Cell Shape and Structure with High-Throughput (HT) Imaging
    Organelle structure has been studied and visualized for decades; however, publicly available databases that use improved high-throughput microscopy of gene-edited cell lines have recently...

    Keywords: modelingcase studymicroscopystructureOrganellesHigh-throughput (HT)Endoplasmic Reticulum (ER)Fluorescent microscopyHuman Cell Biology

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    2017-Guy-Bart_Stan-Modelling in Biology
    This is a very rich set of notes, rich in examples and ideas for modeling. In almost all cases after a model is introduced in real context there is attention to stability analysis.

    Keywords: spring massbifurcationmass actionlimit cycles

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    2006-Michael_Coleman-Population Modeling with Ordinary Differential Equations
    We will investigate some cases of differential equations population models beyond the separable case and then expand to some basic systems of ordinary differential equations.

    Keywords: population dynamics

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    2010-Singh-Mishra-athematical modeling approach to study growth rate of grassroots technological innovations
    In this paper we have proposed a simple mathematical model by using ordinary differential equation to know the spread rate of technological innovations in rural India.

    Keywords: logisticexponentialsigmoidtechnological innovationsasymptoticspread of innovation

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    2005-DieboldEtAl-Modeling Bond Yields In Finance And Macroeconomics
    From a macroeconomic perspective, the short-term interest rate is a policy instrument under the direct control of the central bank. From a finance perspective, long rates are risk-adjusted averages...

    Keywords: financeinterest ratebond yieldmacroeconomics

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    2015-Brian_Winkel-Informed_Conjecturing_of_Solutions_for_Differential_Equations_In_a_Modeling_Contex
    We examine (1) first order exponential growth or decay and (2) second order, linear, constant coefficient differential equations, and show the advantage of learning differential equations in a...

    Keywords: exponential growthsolutionslinear systemsdecayconjecture

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    1-054-GrowthInFarmland-ModelingScenario
    An enriching project developing a model from data with missing temporal information is described. Students fit functions to the data that leads to the creation of a differential equations model,...

    Keywords: fittingfarmfarmland

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    3-072-EarthQuakePartI-ModelingScenario
    This modeling scenario considers a one-story building as a simple structure; the roof is modeled as a single point mass. Movement of the roof can be modeled similar to a mass-spring system.

    Keywords: earthquakevibrationamplituderesonanceundampedspring-mass system

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    6-018-ExploringSIRModel-ModelingScenario
    Students will transform, solve, and interpret Susceptible Infected Recovered (SIR) models using systems of differential equation models. The project is progressively divided into three parts to...

    Keywords: population dynamicssensitivitydiseaseSIR modelsepidemicrumors

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    1-018-LogisticPopModel-ModelingScenario
    We offer artificial (toy) and historical data on limited growth population situations in the study of protozoa and lead students through several approaches to estimating parameters and determining...

    Keywords: data analysisparameter estimationlogisticCiliate protozoapopulationlimited growthparameciaGause

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    Cell Collective: Learning biology with modeling and simulations
    Cell Collective is an online, research-grade modeling platform adapted to engage students in creating and simulating dynamic models of biological processes.

    Keywords: modelingsimulationSimulationsCell Collective

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    Neighborhood Fences and Gates
    This classroom modeling project targets the competency of proposing functions that meet certain properties and features, which is part of many modeling processes. It is suitable for high school or...

    Keywords: function fittingcultural context

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