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    Harnessing the Power of the Immune System: Influenza Vaccines
    Because most people have been infected by and/or immunized against influenza, students should know how the immune system responds to the infection and how vaccines protect against disease. Vaccines...

    Keywords: VaccinesInfluenzaImmunizationVaccine efficacy

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    A Lesson on Matter and Energy at the Organismal Scale: Linking Patterns and Processes Across Diverse Taxa
    Pathways and transformations of energy and matter (PTEM) are a conceptually challenging but essential component of biological literacy. Curricular gaps about PTEM nevertheless remain; although...

    Keywords: plantsenergyAnimalsfungimatterorganismal scale

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    Using Student Perceptions and Cooperative Learning to Unpack Primary Literature on Global Change
    This case describes a three-part assignment in which students discuss key processes that regulate the stability and resilience of the Earth system and our increased risk of generating large-scale...

    Keywords: global changeAnthropoceneEarth-systemplanetary boundary conceptthresholds

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    Life Is Just a Game: An Active Learning Activity to Teach Life History Evolution
    A novel activity was designed to introduce students to the concepts of natural selection and life history using an active-learning, constructivist format. It consisted of two parts: 1) a brief...

    Keywords: Evolutionlife historytrade-offsdiversityNatural Selection

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    What is Speciation, How Does It Occur, and Why Is It Important for Conservation?
    Speciation provides a framework for classifying biodiversity on Earth and is a central concept in evolutionary biology. To help undergraduate students learn about speciation, we designed a...

    Keywords: EvolutionconservationGenetic DriftSpeciationNatural SelectionBiological species conceptgene flowMorphological species conceptPhylogenetic species concept

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    From Cre/LoxP to Fate Maps: Inclusive and Equitable Approaches for Engaging Developmental Biology Students in Experimental Design
    Engaging first generation underrepresented minority students in the process of inquiry in developmental biology is important to increase diversity in future graduate STEM education. One important...

    Keywords: experimental designC. elegansCre/LoxPFate mapheart developmentheart regenerationmousereporter constructzebrafish

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    Necessary and Sufficient? Solving the Mystery of the Mitochondrial Pyruvate Transporter
    While there are several available lessons for teaching introductory biology students about diffusion, facilitated diffusion, and active transport, fewer materials exist to support upper-division...

    Keywords: DiffusionActive transportfacilitated diffusionNecessary and sufficientTransport proteins

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    Translating Co-Translational Translocation
    Understanding the process of proteins targeting to specific locations within a cell is a fundamental part of cell biology. Synthesis of proteins by co-translational translocation, which also...

    Keywords: Topologyco-translational translocationendoplasmic reticulumprotease protection assaysecretory proteinssignal sequencetransmembrane proteins

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    Fruit Fly Genetics in a Day: A Guided Exploration to Help Many Large Sections of Beginning Students Uncover the Secrets of Sex-linked Inheritance
    Moving beyond the basic concepts of autosomal Mendelian inheritance to sex-linkage can be difficult for introductory biology students. Although crosses with Drosophila fruit flies have long been a...

    Keywords: Mendelian Geneticsfruit fly biologysex-linked inheritance

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    The impact of diet and antibiotics on the gut microbiome
    The goal of this article is to describe an active learning exercise that can be used in a variety of advanced microbiology courses, including bacterial physiology, ecology, or systems biology. The...

    Keywords: microbiomeenvironmental controlhost responsemetabolites

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    A Short Bone Biomechanics Primer: Background for a Lesson on Bone Viscoelasticity
    The skeletal system is the first of the body systems that we discuss in-depth in our Physiology & Anatomy courses (PNB 2264/2265 and PNB 2274/2275) in the Department of Physiology and...

    Keywords: structure-functionbiomechanicsAnisotropyViscoelasticity

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    CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate students
    Providing undergraduate life-science students with a course-based research experience that utilizes cutting-edge technology, is tractable for students, and is manageable as an instructor is a...

    Keywords: bioinformaticsPCRphenotypingCRISPR/Cas9gene editingcloningGenotypingRestriction enzyme

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    Furry with a chance of evolution: Exploring genetic drift with tuco-tucos
    Genetic drift is an important mechanism of evolution, yet undergraduates often fail to understand how it leads to evolutionary change due in part to its random nature. This lesson plan describes a...

    Keywords: EvolutionGenetic DriftBottle neckFounder effectRandom evolutionary processes

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    Forensic Phylogenetics: Implementing Tree-thinking in a Court of Law
    Here we describe an in-class activity developed for Evolutionary Biology and Biodiversity (BioEE1780) at Cornell University, an introductory course required of all biology majors. This activity...

    Keywords: phylogeneticsTree thinkingparaphyly

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    A virtual laboratory on cell division using a publicly-available image database
    Cell division is a key concept in cell biology. While there are many popular activities to teach students the stages of mitosis, most make use of simple schematics, cartoons, or textbook diagrams....

    Keywords: image analysismicroscopymitosisCellular Processes

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    Quantifying and Visualizing Campus Tree Phenology
    Large enrollment courses present a challenge for instructors who want to engage students in authentic science practices that fit the recommendations of Vision & Change. Our lesson provides a...

    Keywords: ecologyBiodiversityphenologyplant biology

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    Implementing active learning approaches into an upper-division biology course
    In this essay, we present our strategy for implementing active learning strategies into an upper division course on Human Genetics. Our principal goal was to shift from a traditional didactic...

    Keywords: human biologyPedigree analysisRare genetic diseases

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    Discovery Poster Project
    Engaging in undergraduate research can be exciting yet intimidating to first-year students at large research universities. For first-generation college students, whose pre-college exposure to...

    Keywords: researchprimary literaturePostercore concepts

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    GMC: Genes, Mutations and Cancer - Group Concept Map Development
    It has been shown that active learning strategies used in the classroom can increase student learning and retention of information. We generated an active learning exercise that can be used in the...

    Keywords: mutationcancerCell Division

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    Meiosis: A Play in Three Acts, Starring DNA Sequence
    Meiosis is well known for being a sticky topic that appears repeatedly in biology curricula. We observe that a typical undergraduate biology major cannot correctly identify haploid and diploid...

    Keywords: recombinationmeiosisDNA sequenceCrossingoverchromosome structureHolliday junctionhomology

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