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    Tackling "Big Data" with Biology Undergrads: A Simple RNA-seq Data Analysis Tutorial Using Galaxy
    Analyzing high-throughput DNA sequence data is a fundamental skill in modern biology. However, real and perceived barriers such as massive file sizes, substantial computational requirements, and...

    Keywords: bioinformaticsDNA sequenceRNAseqgene expression

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    The impact of diet and antibiotics on the gut microbiome
    The goal of this article is to describe an active learning exercise that can be used in a variety of advanced microbiology courses, including bacterial physiology, ecology, or systems biology. The...

    Keywords: microbiomeenvironmental controlhost responsemetabolites

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    Cold blood and wet skin in hot and dry secondary forests. How do amphibian traits determine persistence in secondary forests?
    Students will synthesize information from biological and physiological traits of amphibians and characteristics of secondary forests in the tropics to form hypotheses about persistence of...

    Keywords: life historyconservation biologyphysiological ecologyamphibianland use changeEctothermsecondary foresttrait-based ecology

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    Restoring tropical forests: Is planting clusters of trees a cost-effective and ecologically-sound strategy to restore tropical forest?
    This module (available in four languages) provides a broad introduction to both ecological and social aspects of tropical forest restoration. It focuses on a long-term study comparing three...

    Keywords: Restoration Ecologyforest restorationtropical forest

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    Snapshot Serengeti: Implementing an online module about Serengeti wildlife ecology in a community-college ecology course
    This resource describes the implementation plan for an undergraduate ecology course at Muscatine Community College, Iowa, of an online module featuring a database on Serengeti wildlife populations....

    Keywords: ecologywildlifewildlife managementWildlife ecology

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    2011-Lorelei_Koss-Sustainability_in_a_differential_equations_course_case_study_of_Easter_Island
    Easter Island is a fascinating example of resource depletion and population collapse, and its relatively short period of human habitation combined with its isolation lends itself well to...

    Keywords: differential equationssustainabilitypopulationEaster Islandcollapseenvironmental collapse

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    Happy Blue Baby
    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved on its own...

    Keywords: mutationHemoglobinmolecular visualization and analysisgenetic basisPDBMolecular Case StudyMol*

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    MathBench: Biodiversity Assessment of Stream Biota
    The MathBench module, "The Case of the Missing Mountaintop" introduces students to the concept of biodiversity and measures used to quantify biodiversity and stream health. Students investigate the...

    Keywords: ecology labCommunity Ecologyenvironmental scienceconservation ecologyStream ecology

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    A CRISPR/Cas Guide RNA Design In Silico Activity
    CRISPR biotechnologies inspired by the Clustered Regularly Interspaced Short Palindromic Repeat RNA-guided nuclease adaptive bacterial immune system have revolutionized biology research and become...

    Keywords: bioinformaticsgene expressiongenetic basis of diseaseCRISPR/Cas9genetic engineeringin silico

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    Using genomic data and machine learning to predict antibiotic resistance: a tutorial paper
    Antibiotic resistance is a global public health concern. Bacteria have evolved resistance to most antibiotics, which means that for any given bacterial infection, the bacteria may be resistant to...

    Keywords: Tutorialmachine learningantibiotic-resistanceArtificial Intelligence

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    Plant-microbial mutualisms in canopy gap recovery: How do soil microbial symbionts help tropical forests recover from treefall gaps?
    This module uses tropical plant-soil microbial interactions in canopy gaps as a lens to better understand species interactions and disturbance ecology, while showing how scientists study these...

    Keywords: forest ecologyPlant Ecologynutrient cyclingmicrobestropical forestsDisturbances

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    Sexual Dimorphism CURE: Exploring Melanized Wing Patterns of Pieridae Butterflies
    Teach a Course-based Undergraduate Research Experience (CURE) using digitized natural history collections data to test hypotheses on sexually dimorphic wing melanization patterns of Pieris rapae...

    Keywords: data analysismorphologyidigbiosexual dimorphismdata managementImageJsexual selectionnatural history collectionsbutterflycourse-based research experiences (CUREs)digitized natural history collectionsQGISmorphometricsBCEENETgeoreferencing

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    Vitamin C for Colds? Writing LETTERS to Synthesize and Communicate Results from Multiple Studies
    Interpreting experimental results is a key part of evidence-based reasoning. However, it is challenging for students to synthesize data from multiple sources to reach their own conclusions. As...

    Keywords: pre-healthphysiologyScience Communicationscientific literacyScientific Processconventional wisdomscientific methods

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    Make It Stick: Teaching Gene Targeting with Ribbons and Fasteners
    Manipulating gene expression is a commonly used tool to study the effect of a single gene or the hierarchy of gene networks in many different biological disciplines. When working with mice, the...

    Keywords: mathematical modelhomologous recombinationCre/loxgene targeting

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    Grow the Gradient: An interactive countercurrent multiplier game
    The countercurrent multiplier of the loop of Henle in a mammalian kidney is a challenging concept for instructors to teach and for students to learn. We developed an interactive game to support...

    Keywords: countercurrent multiplierexcretory systemkidneyloop of Henlemembrane transport

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    A CURE for Salmonella: A Laboratory Course in Pathogen Microbiology and Genomics
    Rapid advances in genomics and bioinformatics, the vast amount of data generated by next-generation sequencing, and the penetration of the ‘-omics’ into many areas of biology have created a need...

    Keywords: epidemiologyresearchbioinformaticsgenomicspublic healthAntibiotic Resistant BacteriaSalmonellaDNA sequencingpathogenic bacteria

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    A Hands-on Introduction to Hidden Markov Models
    In this Lesson, we describe a classroom activity that demonstrates how a Hidden Markov Model (HMM) is applied to predict a eukaryotic gene, focusing on predicting one exon-intron boundary. This HMM...

    Keywords: transcriptionexonintronsplicing

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    Learn Biological Sciences and Mathematics through cellular respiration, photosynthesis and primary productivity.
    Photosynthesis is a process by which plants synthesize glucose and oxygen in presence of sunlight through light dependent reactions by utilization of sunlight, water to synthesize oxygen, ATP and...

    Keywords: mathematicssimulationThe Analysis of Biological DataMetabolic Pathwaysprocess of sciencephotosynthesisqbccBiological ScienceshypothesisCellular Respirationprimary productivity

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    2015-Lorelei-Koss-Differential Equations In Art and Film
    This paper investigates how differential equations models have been used to study works in literature, poetry and film.

    Keywords: literatureartfilmpoetryreligionmythology

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    What is Speciation, How Does It Occur, and Why Is It Important for Conservation?
    Speciation provides a framework for classifying biodiversity on Earth and is a central concept in evolutionary biology. To help undergraduate students learn about speciation, we designed a...

    Keywords: EvolutionconservationGenetic DriftSpeciationNatural SelectionBiological species conceptgene flowMorphological species conceptPhylogenetic species concept

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