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    Using Musical Instruments to Model Negative Feedback in the Hypothalamo-Pituitary-Target Gland Axes
    Homeostasis and negative feedback are crucial, yet difficult, concepts for undergraduates, particularly in the context of the hypothalamo-pituitary axes. This interactive activity was designed to...

    Keywords: cell-cell communicationhomeostasisnegative feedback

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    2012-Jambhekar-Breen-Extravascular Routes Of Drug Administration in Basic Pharamacokinetics
    This provides an excellent step-by-step of the physiology, construction of model, and notions like peak concentration as well as issues like lag time.

    Keywords: concentrationphysiologydrugslag timeExtravascularPharamacokineticspeak time

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    Antigen presentation and cytotoxic T lymphocytes (CTLs): elucidating a common roadblock for students
    Active learning resource for pre-Nursing anatomy and physiology lecture explaining antigen presentation to CTLs and how the CTLs recognize and destroy the pathogen using Biointeractive animations...

    Keywords: Resources @ HHMI - BioInteractiveimmune systemAnatomy & PhysiologyCell communication

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    Electrical Activity of Neurons
    This tutorial describes how neurons generate action potentials, and how scientists measure neuronal activity and record the firing of individual neurons.

    Keywords: Resources @ HHMI - BioInteractiveAnatomy & PhysiologyNervous systemCell communication

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    Transpiration
    In this lab, students will examine differences between C3 and C4 plants in their transpiration rates.

    Keywords: plant physiologybotanylaboratoryResource Type

    1985

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    One species, two species, red species, lead species? Phylogenetics and species concepts with Plethodon salamanders
    This lab introduces students to species concepts and basic computer-based tree-building methods using published nuclear and mitochondrial sequence data for Plethodon salamanders.

    Keywords: phylogenetic analysisTree thinkingsalamanderAudience level - Advanced UG

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    Using Regression Models to Examine the Effect of Carbon Dioxide on Fluid pH
    In this activity students will use statistics and regression models to explore the effects of carbon dioxide on blood pH by measuring pH changes that occur over time as carbon dioxide reacts with...

    Keywords: BiochemistryphysiologyAnatomyGeneral BiologyChoosing modelsCreate graphsInterpret graphsConcepts in Statisticscreate modelsmake predictions

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    2006-Han-EtAl-Ordinary differential equation models for ethanol pharmacokinetic based on anatomy and physiology
    Physiologically-based pharmacokinetic (PBPK) models have been used to describe the distribution and elimination characteristics of intravenous ethanol administration.

    Keywords: liverwortsintraveneouspharmacokineticsethanolethanol infustionpharmacodynamictissue model

    116

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    Regulation of Sex Determination
    This activity accompanies the HHMI BioInteractive module Sex Verification of Athletes (​https://www.hhmi.org/biointeractive/testing-athletes​). It provides students with exercises to explore the...
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    2007-Zenker-Rubin-Clermont-From inverse problems in mathematical physiology to quantitative differential diagnoses
    The improved capacity to acquire quantitative data in a clinical setting has generally failed to improve outcomes in acutely ill patients, suggesting a need for advances in computer-supported data...

    Keywords: physiologyinverse problem

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    Investigating Gene Expression and Cell Specialization in Axolotl Embryos
    The process of cell specialization is critical to the formation and function of tissues in animals and plants. Although gene expression, including the regulation of transcription, is taught in most...

    Keywords: developmenttranscriptiongene expressionmodel organismembryo

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    1-132-DigoxinElimination-ModelingScenario
    We model the concentration of digoxin eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the study...

    Keywords: nullclinespharmacokineticsdigoxindrug eliminationtwo compartment

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    Sin Nombre Hantavirus in the US
    A module guiding students through the review of different biodiversity data sources to identify patterns in the distribution of the Sin Nombre Hantavirus in the United States. English, Spanish, and...

    Keywords: Resources @ AIM-UP!infectious diseasespublic healthnatural history collectionsWildlife Diseasedigitized natural history collectionsenglishSpanishzoonotic diseaseshantavirusMEPAPortuguesetranslated

    675

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    Analyzing Data on Behavioral and Immunological Effects of Inflammation in Mice
    In this activity, students will learn about behavioral and immunological responses to a bacterial infection. The activity emphasized the host’s responses rather than bacterial manipulation of the...

    Keywords: Vision and Changedata analysisImmunologybehaviorphysiologyinflammationinterdisciplinary educationAntigenmouseImmunoReachSicknessleukocyteneutrophilLipopolysaccharideacute phase response

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    Two-Species Model
    These two Excel worksheets simulate the population growth of two interacting species. In isolation, each species grows logistically, but interaction effects between species may limit or enhance...

    Keywords: population growthcompetition modelsLotka-Volterra

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    Serial Dilutions
    In this Excel workbook, users will enter the original cell concentration and the desired dilution factor (10, 100, and 1000). The program will then calculate the new cell concentration.

    Keywords: concentrationScientific Notationorders of magnitudeserial dilutions

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    Phylogeography Simulator
    This Excel workbook simulates the phylogeography of an asexually reproducing species.

    Keywords: Phylogeographymutation ratesAsexual reproductionspecies dispersal

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    Examining the Physiology Behind the Symptoms of Lactose Intolerance
    This is a set of extension questions for the HHMI short film The Making of the Fittest: Got Lactase? The Co-evolution of Genes Video Activity.
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    Pivoting Intro from Inquiry to Online
    This poster will present how inquiry-based learning experiences that were designed for face-to-face labs can be modified in a rapid pivot to online teaching.

    Keywords: plant physiologybotanyonline learninginquiry-based learningtranspirationonline labremote

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    Sex Verification Testing of Athletes
    This interactive module explores the biology of sex determination and development in humans, set against the backdrop of the different sex testing policies implemented throughout sports history.

    Keywords: Resources @ HHMI - BioInteractiveDevelopmental BiologyAnatomy & PhysiologyScience & SocietySex hormoneshuman reproductive development

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