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    Sanger Sequencing by Hand: Using Paper Clips to Demonstrate Chain Termination
    Sanger sequencing is commonly taught with a hands-on approach. Sanger sequencing involves chain termination by dideoxynucleotides, because they are missing the oxygen on the 3’ carbon atom,...

    Keywords: nucleotidessequencingDNAgel electrophoresisChain Termination

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    Squirreling Around for Science: Observing Sciurid Rodents to Investigate Animal Behavior
    Hands-on research experiences are important opportunities for students to learn about the nature of inquiry and gain confidence in solving problems. Here, we present an inquiry-based lesson plan...

    Keywords: foragingbehaviorbehavioral ecologySciuridSquirrelSquirrel-NetTrade-offVigilance

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    The Science Behind the ACTN3 Polymorphism
    A common polymorphism in the alpha-actinin-3 (ACTN3) gene results in the lack of ACTN3 protein expression in fast twitch muscle fibers in ~16% of the human population (1). This genetic change has...

    Keywords: protein structure and functionhuman genetic variationskeletal muscle physiology

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    Starting Conversations About Discrimination Against Women in STEM
    Many scientists know about — and experience — discrimination against women. In this professional development lesson, graduate students, postdoctoral fellows, faculty, and other career...

    Keywords: identityracismGender discriminationIntersectionalityMicroagressionsSexismSexual assaultSexual harassmentTrolling

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    The Three Sisters of Agriculture: An Active Learning Activity on Symbiotic Nitrogen Fixation
    This active learning exercise introduces students to the plant microbiome and the contributions that bacteria make to plant growth and food production. The Three Sisters are an ancient indigenous...

    Keywords: SymbiosisPlant microbiomeNitrogen fixationNutritional content of foodElectron flowSociety impact of microorganisms

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    Animal Behaviour Case Study Lessons in Communication, Migration, and Parental Care Using the Jigsaw Approach
    Animal behaviour courses integrate concepts across biological disciplines and are particularly well suited for collaborative, student-focused teaching...

    Keywords: case studycommunicationprimary literatureanimal behaviorjigsawParental CaremigrationAnimal BehaviourProximate mechanisms

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    Integrating Community Ecology Into the Study of Parasites: Exploring the Effect of Host Behavior on Parasite Transmission Rates
    Organismal life cycles are often presented as a set of facts to memorize in undergraduate biology courses. This approach is cognitively demanding for students and fails to convey how central life...

    Keywords: statisticsspecies interactionsQuantitative reasoninggraphsCommunity EcologyParasitologyfood webs

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    Problem-Based Learning for Physiology: Synthesizing the Cardiovascular System, Respiration, Macronutrient Metabolism, and Renal Function
    Problem Based Learning (PBL) is a valuable tool for helping students overcome reliance on memorization by scaffolding opportunities for them to practice the competency of...

    Keywords: MetabolismObesityblood pressurecardiac functioncardiovascularmetabolic syndromerenalRespirationrespiratory system

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    An Introduction to the Squirrel-Net Teaching Modules
    Although course-based undergraduate research experiences (CUREs) are gaining popularity in biology, most are designed for benchwork-based laboratory courses while few focus on field-based skills....

    Keywords: ecologybehaviortrade-offsScientific ProcessSquirrel-Net

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    An Inquiry-Based Project Added to Traditional Labs: Hands-On Fish Awareness Research in Freshwater Systems Conducted by First-Year Biology Students
    This project involves students in an inquiry-based project added to the introductory biology laboratory course for majors in fall 2019. Research has shown that student engagement in authentic...

    Keywords: Evolutionbehaviorichthyology

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    Learning How to Make “Good Enough” Estimations
    The ability to estimate physical quantities is a useful skill that can help develop critical thinking and scientific literacy. This lesson provides an accessible way to teach students how to...

    Keywords: MeasurementestimationcommunicationProblem Solvinggroup workUnit conversion

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    Using Images of Foraging Leaf-Cutter Ants to Teach Linear Regression
    This lesson offers students a realistic, open-inquiry research experience, even when lab or field research is not possible. We first introduce students to leaf-cutter ants and how they forage. Then...

    Keywords: linear regressionexperimental designPlant-insect interactionsSymbiosisForaging behavior

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    Vitamin C for Colds? Writing LETTERS to Synthesize and Communicate Results from Multiple Studies
    Interpreting experimental results is a key part of evidence-based reasoning. However, it is challenging for students to synthesize data from multiple sources to reach their own conclusions. As...

    Keywords: pre-healthphysiologyScience Communicationscientific literacyScientific Processconventional wisdomscientific methods

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    A virtual laboratory on cell division using a publicly-available image database
    Cell division is a key concept in cell biology. While there are many popular activities to teach students the stages of mitosis, most make use of simple schematics, cartoons, or textbook diagrams....

    Keywords: image analysismicroscopymitosisCellular Processes

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    Out of Your Seat and on Your Feet! An adaptable course-based research project in plant ecology for advanced students
    University capstone projects can offer science students a rich research experience that illustrates the process of doing scientific research, and can also help students better choose future...

    Keywords: statisticsactive learningecologyinterdisciplinaryplantscommunicating sciencegroup workfield workproces of science

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    Authentic Ecological Inquiries Using BearCam Archives
    Learning through authentic scientific inquiries is essential for understanding the nature and process of science and for developing critical thinking and communication skills. It is logistically...

    Keywords: behaviorinterspecific interactionsPeer reviewauthentic inquiryintra-specific interactions

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    Keep It Shrimple: An Adaptable Student-Driven Research Project for the Introductory Biology Laboratory
    A challenge in introductory biology laboratory courses is to provide students with authentic, engaging research opportunities that allow them to take ownership of their experiments. We present a...

    Keywords: hypothesis testingexperimental designanimal behaviorbrine shrimp

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    A Laboratory Module That Explores RNA Interference and Codon Optimization Through Fluorescence Microscopy Using Caenorhabditis elegans
    Scientific research experiences are beneficial to students allowing them to gain laboratory and problem-solving skills, as well as foundational research skills in a team-based setting. We designed...

    Keywords: microscopyC. elegansquantitative analysisinquiry-based learninggene expressionRNA interferenceCodon UsageLaboratory Module

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    A CURE for Salmonella: A Laboratory Course in Pathogen Microbiology and Genomics
    Rapid advances in genomics and bioinformatics, the vast amount of data generated by next-generation sequencing, and the penetration of the ‘-omics’ into many areas of biology have created a need...

    Keywords: epidemiologyresearchbioinformaticsgenomicspublic healthAntibiotic Resistant BacteriaSalmonellaDNA sequencingpathogenic bacteria

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    Cutthroat trout in Colorado: A case study connecting evolution and conservation
    Evaluation of evidence is a key process skill for the core competencies of applying the process of science and using quantitative reasoning. This case study enables upper-division biology students...

    Keywords: population geneticsphylogeneticsSpeciationdivergencegene flow

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