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    Targeting Infected Cells for Immune Defense
    This animation shows how a cell infected by a virus signals cytotoxic T cells to destroy itself.

    Keywords: Resources @ HHMI - BioInteractiveimmune systemAnatomy & PhysiologyCell communication

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    Online Adaptation of the Cell Engineer/Detective Lesson
    One of the most fundamental themes of biology is the relationship between structure and function, which is particularly evident when it comes to cells; however, the traditional cartoon depictions...

    Keywords: cell functionCell StructureOrganelles

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    2002-Nelson-Perelson-Mathematical analysis of delay differential equations models of HIV-1 infection
    We develop and analyze a set of models that include intracellular delays, combination antiretroviral therapy, and the dynamics of both infected and uninfected T cells.

    Keywords: infectionHIVT cells

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    Antigen presentation and cytotoxic T lymphocytes (CTLs): elucidating a common roadblock for students
    Active learning resource for pre-Nursing anatomy and physiology lecture explaining antigen presentation to CTLs and how the CTLs recognize and destroy the pathogen using Biointeractive animations...

    Keywords: Resources @ HHMI - BioInteractiveimmune systemAnatomy & PhysiologyCell communication

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    A virtual laboratory on cell division using a publicly-available image database
    Cell division is a key concept in cell biology. While there are many popular activities to teach students the stages of mitosis, most make use of simple schematics, cartoons, or textbook diagrams....

    Keywords: image analysismicroscopymitosisCellular Processes

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    Does Organelle Shape Matter?: Exploring Patterns in Cell Shape and Structure with High-Throughput (HT) Imaging
    Organelle structure has been studied and visualized for decades; however, publicly available databases that use improved high-throughput microscopy of gene-edited cell lines have recently...

    Keywords: modelingcase studymicroscopystructureOrganellesHigh-throughput (HT)Endoplasmic Reticulum (ER)Fluorescent microscopyHuman Cell Biology

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    Spreadsheet Tutorial 4: t-Test
    Calculate t-values and perform t-tests using built-in functions.

    Keywords: Resources @ HHMI - BioInteractiveScientific ProcessStatistics and MathScientific Methodology

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    Using the IEDB to Predict Proteasomal Cleavage Events and T-cell Epitopes
    Research experiences provide a valuable view into the world of science and a great way to explore new fields and careers while developing critical thinking skills. The development and maintenance...

    Keywords: biologydatabaseImmunologydata sciencebioinformaticsBiotechnologyt-cellengineeringantibodyBioengineeringAntibody EngineeringlymphocytesProteinNetChopepitopeIEDBB-cellProteasomeProteasomal Cleavage

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    Immunity and Vaccine Action
    From the cellular level on up, being aware of your interactions can help you stay safe. This resource addresses fundamental immunology and infectious disease concepts through a historical...

    Keywords: immunology educationvaccine literacyvaccine hesitancy

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    BioNumbers: The Database of Useful Biological Numbers
    A database of biological numbers that you can search and browse.
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    Bioimage Informatics Activity
    Students use basic bioimage informatics techniques to acquire quantitative data from images of cultured cells and test a hypothesis about the effect of a genetic mutation on cellular phenotypes

    Keywords: geneticsResources @ HHMI - BioInteractivegenomicscancergenetic basis of diseasebiology of cells

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    Growing Lung Carcinoma and Lung Fibroblast Cell Lines
    Basic information on how to grow Lung Carcinoma and Lung Fibroblast Cell Lines.

    Keywords: tipsCell Growthcell cultureA-549HFL-1

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    Lights, Camera, Acting Transport! Using role-play to teach membrane transport
    Lights, Camera, Acting Transport! is an active and unique role-play exercise designed to teach introductory biology students basic concepts of passive and active membrane transport. The activity...

    Keywords: ATPcarrierschannelsco-transportelectrogenic pumpfacilitated diffusionmembrane transportpassive transportprimary active transportsimple diffusion

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    Fatty Acid Induction of Lipid Droplets in Cancer Cells
    There is a growing need for the development and communication of cell culture-based laboratory activities specifically designed for undergraduate students. This multi-week laboratory activity...

    Keywords: Course based undergraduate researchCell ImagingLive Cell Staining

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    How to Grow Specific Cell Lines: Liver Cancer Cell Lines (SNU-423 and Hep-G2)
    General information for growing cell lines. One is a high-grade (fast) cancer the other is a low-grade. Makes for great comparisons within a class setting.

    Keywords: tipsCell GrowthHepG2SNU-423 ATCC

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    Easy Hypoxia Treatments for Cell Culture a CBEC Cell Block
    A combination of ideas we have found from various sources. These can be used in an undergraduate lab or Cell CURE.

    Keywords: hypoxia

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    Mechanisms of Cell Attachment
    This module introduces the calculation of refractive indices along a cell surface in the context of understanding the attachment of cells to surfaces. It is intended for an introductory biology...

    Keywords: GeometryCell StructureCell GrowthSimple EquationsInterpreting GraphCell Attachment

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    1-005B-ChemDataCollection-ModelingScenario
    A chemistry graduate student is collecting data on a chemical reaction and does a poor job of collecting the data. Indeed, he only collects the data at the start and end of a number of three minute...

    Keywords: kineticslaboratoryorder of reactionchemical reactionchemical datainfusion

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    Citations
    Published Avida-Ed article

    Keywords: EvolutioncurriculumSelectionDigital Organisms

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    Scratch Assay (Cell Migration) Cell Block
    A video tutorial and pedagogy notes describing how to measure cell migration using a wound/scratch assay. This is an inexpensive and relatively easy experiment. A micropublication that used this...

    Keywords: wound healingcourse-based research experiences (CUREs)Cell culture-based researchScratch AssayCell migrationCancer cell biology

    61

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