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    Assessing in vivo Antimicrobial Activity Through the Analysis of Galleria mellonella Kaplan-Meier Plots
    Antimicrobials and their use in the treatment of bacterial infections are a fundamental lesson in all microbiology courses. Typically, cultivation-based methods are used to teach students about...

    Keywords: Antimicrobial TestingAntimicrobialsInvertebrate animal models

    1984

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    Fatty Acid Induction of Lipid Droplets in Cancer Cells
    There is a growing need for the development and communication of cell culture-based laboratory activities specifically designed for undergraduate students. This multi-week laboratory activity...

    Keywords: Course based undergraduate researchCell ImagingLive Cell Staining

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    1-064-TorricelliBox-ModelingScenario
    The time it takes a column of water to empty and the time it takes the same volume of column of water with a box (various sizes) submerged in the column of water are compared through modeling with...

    Keywords: groundwater flowcolumn of waterTorricelli's Lawwater displacementsubmerged box

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    Taking the Hassle out of Hasselbalch
    Mention pH in a classroom and you can almost see the inner yawn on the faces of your students. The definition may even roll easily from their lips. However, despite multiple exposures to the...

    Keywords: pHdrug uptakeHenderson-Hasslbalch equationmedical applicationspKa

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    3-040-FirstPassageTime-ModelingScenario
    We apply the notions of dampedness to second order, linear, constant coefficient, homogeneous differential equations used to model a spring mass dashpot system and introduce the notion of first...

    Keywords: oscillatordampedunderdampedfirst passagefirst passage timespring mash dashpot

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    Liberating Data for Biodiversity Research
    The objectives of this exercise are to familiarize you with the information content of biodiversity specimens and their labels, the breadth of that information across geographic space and/or time.

    Keywords: Biodiversitynatural history collectionsBLUEresearch specimensbiodiversity dataspecimen labels

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    3-044-DeepWell-ModelingScenario
    We drop a pebble in a deep well. Given the time elapsed from release of the pebble until we hear the splash determine the depth of the well.

    Keywords: gravityprojectile motionfalling bodyspeed of sound

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    2019-Stender_EtAl-Recovery_Of_Differential_Equations_From_Impulse_Response
    In this work, a recent method, which allows reconstructing differential equations from time series data, is extended for higher degrees of automation.

    Keywords: time seriesregressionresponseimpulseoscillationsignal processingsparse regressionsystem identification

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    6-067-LotkaVolterra-ModelingScenario
    This modeling scenario guides students through the process of fitting the Lotka-Volterra model of two differential equations to a real time series observational data. Students use the capabilities...

    Keywords: time seriesdatacompetitionLotka-Volterramodel fittingpredictiongauseRexperimental

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    1999-Leonid_Hanin-Which tank empties first
    Suppose that water towers like those shown in the opening are initially filled with water and have the same volume, height, and cross-sectional outlet area. Which one empties first?

    Keywords: tankTorricelli's Lawspherical tankemptyfrustrum of conecylinder

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    CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate students
    Providing undergraduate life-science students with a course-based research experience that utilizes cutting-edge technology, is tractable for students, and is manageable as an instructor is a...

    Keywords: bioinformaticsPCRphenotypingCRISPR/Cas9gene editingcloningGenotypingRestriction enzyme

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    2012-Hassan_Moore-Using projects to stimulate learning in mathematics and engineering mathematics courses
    Given that time is a premium in the academy and project creation is a time consumer, three original projects, which may be injected into any Calculus III, Differential Equations, or Engineering...

    Keywords: solutionsclass projectsphysical phenomenon

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    1-052-SaltWaterTanks-ModelingScenario
    We offer three mixing problems, of increasing order of difficulty, in which salt is coming into a tank of water and upon instantaneous mixing is leaving the tank.

    Keywords: salttankmixing

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    2008-Brewer-EtAl-Fitting ordinary differential equations to short time course data
    In this paper, we present a survey of existing algorithms and describe the main approaches. We also introduce and evaluate a new efficient technique for estimating ODEs linear in parameters...

    Keywords: time seriesEvaluation SPLINEgeneleast squaresbifurcation

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    2012-Yuan_Yuan-A coupled plankton system with instantaneous and delayed predation
    We present two simple plankton population models: one has instantaneous predation, another has delayed predation.

    Keywords: phytoplanktonbifurcationorbitsherbivorous zooplanktoneffect of fishmaturation time delay

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    2005-Minna_Wedenberg-Pharmacokinetic modeling of gastric emptying
    The development of new drug substances is a complex, time consuming and expensive process. Reducing the time for drug development and avoiding late termination of candidate drugs are important...

    Keywords: paracetamolpharmacokineticsstomachsmall intestinesulfapyridine

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    Application of a Bacterial Experimental Evolution System to Visualize and Teach Evolution in Action: A Course-Based Undergraduate Research Experience
    Concepts of evolution are typically taught through examples of extremely long timescales, which do not always resonate broadly. Here, we describe a course-based undergraduate research experience...

    Keywords: EvolutionmutationcompetitionNatural Selectionregulationstructure and functionreproductive fitnessgenotype to phenotypehomologs

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    2017-Anders_Kallen-Single species models in continuous time
    Part of a series of Lecture notes this lecture contains rich materials on logistic harvest models, spruce budworms, and chemostat.

    Keywords: chemostatlogisticharvestspruce budworm

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    Spatial Analysis with QGIS
    Map specimen data points using QGIS, connect them to form a polygon using the Concave Hull plugin, and calculate the range of a species to examine how it changes over time.

    Keywords: natural history collectionsspecies distributionscourse-based research experiences (CUREs)spatial analysisdigitized natural history collectionsQGIS

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    Trout modeling example
    This is an open-ended modeling example using difference equations and Algebra II skills.

    Keywords: population biology

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