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    Birds and Lice: Reciprocal Natural Selection
    This exercise investigates the form and function of lice and their relationship to their bird host.

    Keywords: BiodiversityparasitesbirdsCoevolutionnatural history collections

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    Spreadsheet Tutorial 4: t-Test
    Calculate t-values and perform t-tests using built-in functions.

    Keywords: Resources @ HHMI - BioInteractiveScientific ProcessStatistics and MathScientific Methodology

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    Exploring the functionality of R
    Students work with example data to generate a length-weight plot and use lm() to obtain regression coefficients. Base plot functions are used to plot both the data and the regression line.
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    Follow the Sulfur: Using Yeast Mutants to Study a Metabolic Pathway
    Students are frequently overwhelmed by the complexity of metabolic pathways and they think they have "learned" the pathway when they have memorized the individual reactions.  This...

    Keywords: SelectionyeastMetabolismcysteinemediamethioninemutantPathwaysulfur

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    Conducting Analysis of Variance (ANOVA) in R with swirl
    This lesson offers an introduction to ANOVA, including 1) how this statistical test can be differentiated from others and 2) a step-by-step guide to conducting and interpreting ANOVA results in R,...

    Keywords: biostatisticsR programming languageSwirl

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    The Three Sisters of Agriculture: An Active Learning Activity on Symbiotic Nitrogen Fixation
    This active learning exercise introduces students to the plant microbiome and the contributions that bacteria make to plant growth and food production. The Three Sisters are an ancient indigenous...

    Keywords: SymbiosisPlant microbiomeNitrogen fixationNutritional content of foodElectron flowSociety impact of microorganisms

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    Central Dogma, Dictionaries, and Functions: Using Programming Concepts to Simulate Biological Processes
    Technologies like next-generation sequencing, proteomics, and high-throughput phenotyping have transformed the way we do biology. There is a continued need for scientists with computational skills...

    Keywords: computationpythonJupyter notebookFunctionscentral dogmaDictionaries

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    Evolution of Caffeine Biosynthesis Enzymes
    This case focuses on exploring why plants make secondary metabolites like caffeine and how the enzymes required for making caffeine evolved.

    Keywords: Evolutioncaffeinemolecular visualization and analysisenzymesPDBMolecular Case Study

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    Coronavirus Epidemic Curves - Graphically Interpreting Derivatives
    A set of exam questions or class activity related to 'flatten the curve' during the coronavirus outbreak of 2020. Content includes: notation, first derivative, second derivative, and interpreting...

    Keywords: derivativescalculussecond derivativefirst derivativeInterpreting GraphsCOVID19coronavirus

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    Module M.3 Visualizing data with ggplot2
    Introduction to Primate Data Exploration and Linear Modeling with R was created with the goal of providing training to undergraduate biology students on data management and statistical analysis...

    Keywords: R programming languageprimatespopulation ecology

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    Striped Bass: A Regulatory Success Story
    This module examines the Maryland striped bass moratorium (1985-1989) as a fisheries management success story. Maryland DNR striped bass young of the year data is utilized for least squares linear...

    Keywords: regressionfisheriesmonitoringrecruitmentstriped bassmoratoriumfish biologyfisheries ecologyspawninganadromousyoung of the yearrelative abundancechesapeake bayfish population

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    Sickle Cell Anemia using Nicholas’ Story
    The goal of this exercise is to introduce students to 3-D structures of biological molecules, visualize and manipulate them to understand their functions. The exercise also helps them see the...

    Keywords: Hemoglobinsickle cell diseaseMolecular Case Study

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    Module M.1 R basics for data exploration and management
    Introduction to Primate Data Exploration and Linear Modeling with R was created with the goal of providing training to undergraduate biology students on data management and statistical analysis...

    Keywords: R programming languageprimatespopulation ecology

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    Module M.2 Descriptive statistics
    Introduction to Primate Data Exploration and Linear Modeling with R was created with the goal of providing training to undergraduate biology students on data management and statistical analysis...

    Keywords: R programming languageprimatespopulation ecology

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    Diversity Indices: Shannon's H and E
    This module introduces Shannon's diversity index in the context of understanding how to mathematically measure the species diversity in a community. It is intended for an introductory biology...

    Keywords: ecologydiversityFunctionsOpenStaxdiversity index

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    Genome Sequence Data in R using Biostrings (Swirl Lesson)
    By the end of this lesson, students should be able to load FASTA files into R as DNAStringSets and use width() and alphabetFrequency(), combined with other functions like sum() and mean(), to...

    Keywords: R programming languagecourse-based undergraduate research experienceBioinformatics and GenomicsCURECUREscourse-based research experiences (CUREs)STEM CUREsComparative genomicsBioconductor

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    How to Design a Classroom Activity that Integrates 3D Print Models with Active Learning
    Student exploration of relevant physical models can deepen knowledge of course material. In this guide we describe a method by which instructors can integrate 3D printing technology with an...

    Keywords: active learning3D print modelsclassroom jigsaw

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    2007-Helfgott-Seier-Some Mathematical and Statistical Aspects of Enzyme Kinetics
    We will analyze some basic ideas behind enzyme kinetics, which allow us to deal with separable and linear differential equations as well as realize the need to use power series.

    Keywords: kineticsEnzymeexperimental dataregresion

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    Fragile States: A Case Study Exploring Genetics, Molecular Biology, and Biochemistry Through the Lens of Fragile X Syndrome
    This case aims to strengthen students’ understanding of molecular biology concepts through study of Fragile X Syndrome (FXS). Students begin by learning the cause and phenotypes of FXS and...

    Keywords: gene regulationtranscriptiontranslationFragile X syndrometriplet repeat expansionsex linkagemetabolic pathway

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    Module M.7 Generalized linear mixed-effects models
    Introduction to Primate Data Exploration and Linear Modeling with R was created with the goal of providing training to undergraduate biology students on data management and statistical analysis...

    Keywords: R programming languageprimatespopulation ecology

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