You are here: Home / Resources / Browse Resources

Open. Adaptable. Free.

Resources created by our members and partners.

The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

Text Search:
Applied Filters
    1999-Peter_Deuflhard-Differential Equations in Technology and Medicine
    It deals with a variety of challenging real life problems selected from clinical cancer therapy, communication technology, polymer production, and pharmaceutical drug design.

    Keywords: cancerdesigntumordrugpolymertherapy

    135

    views

    39

    downloads

    0

    comments

    0

    adaptations

    The p53 Gene and Cancer
    This tutorial describes the structure and function of the p53 protein, how its activity is regulated in cells, and how mutant versions of p53 can lead to cancer.

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymolecular biologymacromoleculesGenetic disease

    3328

    views

    426

    downloads

    0

    comments

    1

    adaptations

    1-102C-CancerGrowth-ModelingScenario
    This module guides students in the use of differential equation models to predict cancer growth and study treatment outcomes. Several classical models for cancer growth are presented including...

    Keywords: optimizationcancerlogisticexponentialpredictiontumorgrowthdata fittingpower lawBertanffyGompertz

    346

    views

    223

    downloads

    0

    comments

    0

    adaptations

    6-029-TumorGrowth-ModelingScenario
    This modeling scenario guides a student familiar with single ordinary differential equation (ODE) models towards the development of a more complex system of two ODEs for describing the evolution of...

    Keywords: Pop_Growth Pilotlogisticcomparmenttumorsynthetic datasum of squares error

    199

    views

    223

    downloads

    0

    comments

    0

    adaptations

    Synapse Transmission and Action Potentials
    This module introduces action potentials in the context of understanding nerve impulses. It is intended for an introductory biology audience.

    Keywords: InequalitiesOpenStaxAnimal Physiology

    1000

    views

    232

    downloads

    0

    comments

    0

    adaptations

    2009-Chellaboina-EtAl-Modeling And Analysis-Mass Action Kinetics
    Mass-action kinetics are used in chemistry and chemical engineering to describe the dynamics of systems of reactions, that is, reaction networks. These models are a special form of compartmental...

    Keywords: dynamical systemschemical reactionreaction networkmass action

    160

    views

    38

    downloads

    0

    comments

    0

    adaptations

    Electrical Activity of Neurons
    This tutorial describes how neurons generate action potentials, and how scientists measure neuronal activity and record the firing of individual neurons.

    Keywords: Resources @ HHMI - BioInteractiveAnatomy & PhysiologyNervous systemCell communication

    1249

    views

    247

    downloads

    0

    comments

    1

    adaptations

    Antigen presentation and cytotoxic T lymphocytes (CTLs): elucidating a common roadblock for students
    Active learning resource for pre-Nursing anatomy and physiology lecture explaining antigen presentation to CTLs and how the CTLs recognize and destroy the pathogen using Biointeractive animations...

    Keywords: Resources @ HHMI - BioInteractiveimmune systemAnatomy & PhysiologyCell communication

    1103

    views

    433

    downloads

    0

    comments

    0

    adaptations

    2018-Yu-Craciun-Mathematical_Analysis_of_Chemical_Reaction_Systems
    These models of chemical reactions are systems of coupled nonlinear differential equations on the positive orthant.

    Keywords: biochemicalkineticsreactionreaction networkmass action

    139

    views

    42

    downloads

    0

    comments

    0

    adaptations

    Understanding Gastric Acid Secretion: An Active Learning Approach
    The human digestive system is a diverse network of cells, tissues, and organs that is regulated by systemic (e.g., nervous and endocrine systems) and local factors (e.g., secretions, pH, and the...

    Keywords: diseasesignal transductionAcid SecretionAutonomic Nervous SystemEndocrineGastric PhysiologyGPCRHistology of Gastric Pit

    1140

    views

    547

    downloads

    0

    comments

    0

    adaptations

    Cell Cycle and Mitosis
    This module introduces activities that allow students to walk through the cell cycle and mitotic cell division processes. As part of the activities, students learn about and apply knowledge of...

    Keywords: introductory biologyQuantitative reasoningInterdisciplinary STEMquantitative biologyinterdisciplinaryquantitative skillscell functioncell cyclemitosisCell DivisionMitotic Indexcalculating meanstumorNIQBC2. Data and GraphsC4. mathematical modelsC3. Statistical Analysisstandard errormitotic phaseinterphase

    209

    views

    187

    downloads

    0

    comments

    0

    adaptations

    Doubling Time of Tumors
    This module introduces the calculation of potential doubling time of tumorous cells in the context of understanding the growth of a population of the cells. It is intended for an introductory...

    Keywords: linear regressionRatiosCell StructureOpenStaxCell Growth

    992

    views

    192

    downloads

    0

    comments

    0

    adaptations

    How Do Certain Factors Impact People's Actions Toward Climate Change?
    A survey was conducted to research how age and knowledge about climate change can impact people’s actions regarding it. People have a large impact on the environment so knowing how different groups...

    Keywords: climate change

    512

    views

    43

    downloads

    0

    comments

    0

    adaptations

    Maria vs Malaria - AR Adaptation
    This case study focuses on a specific enzyme Lactate Dehydrogenase (LDH) in the malarial parasite as a target for treating malaria. Students will be able to view selected molecular views from the...

    Keywords: bioinformaticsAugmented RealityLarge class sizemolecular visualizationstructure-functionuniprotProtein Data BankMolecular Case StudyMolecular CaseNet

    433

    views

    249

    downloads

    0

    comments

    0

    adaptations

    2014-Hrydziuszko-EtAl-Mathematical Two-compartment Model of Human Cholesterol Transport
    We develop a two-compartment mathematical model to investigate cholesterol transport in the circulatory system and its de novo synthesis in the liver.

    Keywords: metabolic syndromecompartmentcholesteroltwo-compartment modelcholesterol transport

    125

    views

    74

    downloads

    0

    comments

    0

    adaptations

    Taking the Hassle out of Hasselbalch
    Mention pH in a classroom and you can almost see the inner yawn on the faces of your students. The definition may even roll easily from their lips. However, despite multiple exposures to the...

    Keywords: pHdrug uptakeHenderson-Hasslbalch equationmedical applicationspKa

    1577

    views

    384

    downloads

    0

    comments

    0

    adaptations

    Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson
    There is a growing need for integration of “Big Data” into undergraduate biology curricula. Transcriptomics is one venue to examine biology from an informatics perspective. RNA sequencing has...

    Keywords: bioinformaticscancertranscriptomicshigh-throughputData wranglingSingle cell RNA sequencingq

    6457

    views

    1617

    downloads

    0

    comments

    0

    adaptations

    1-102-CancerTumor-ModelingScenario
    This module guides students in the use of differential equation models to predict cancer growth and optimize treatment outcomes. Several classical models for cancer growth are studied, including ...

    Keywords: optimizationlogisticpredictiondata fittingpower lawGompertzcancer growtheponentialBertalanaffy

    340

    views

    348

    downloads

    0

    comments

    0

    adaptations

    Building a Model of Tumorigenesis: A small group activity for a cancer biology/cell biology course
    The multistep nature of tumorigenesis is a foundational concept in the context of Cancer Biology. Many students do not appreciate the complex nature of cancer development nor do they understand how...

    Keywords: pathwayscancerMolecular AlterationsRetrospective dataTumorigenesis

    1402

    views

    504

    downloads

    0

    comments

    0

    adaptations

    3-095-ShotInWater-ModelingScenario
    This project uses Newton's Second Law of Motion in conjunction with a quadratic model for the resistance experienced by a bullet moving through water to analyze a classic action movie scene.

    Keywords: projectile motionterminal velocityprojectilewater resistancereduction of orderfrictionair resistance

    186

    views

    174

    downloads

    0

    comments

    0

    adaptations

    Close

    Home

    Search