You are here: Home / Resources / Browse Resources

Open. Adaptable. Free.

Resources created by our members and partners.

The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

Text Search:
Applied Filters
    1971-Carl_Metzler-Usefulness Of Two Compartment Open Model In Pharmacokinetics
    Compartment models are widely used in pharmaceutical research to quantitate the kinetics of absorption, distribution, metabolism and excretion of a drug. In this article two applications of the two...

    Keywords: LSDcompartmentpharmacokinetics

    208

    views

    89

    downloads

    0

    comments

    0

    adaptations

    2014-Hrydziuszko-EtAl-Mathematical Two-compartment Model of Human Cholesterol Transport
    We develop a two-compartment mathematical model to investigate cholesterol transport in the circulatory system and its de novo synthesis in the liver.

    Keywords: metabolic syndromecompartmentcholesteroltwo-compartment modelcholesterol transport

    142

    views

    90

    downloads

    0

    comments

    0

    adaptations

    1994-S_S_Everingham-C_Peter_Rydell-Modeling the Demand for Cocaine
    This is a report prepared for the Office of National Drug Control Policy of the United States Army by the Rand Corporation. The report contains lots of data and builds a two compartment difference...

    Keywords: drugstwo compartmentcocainedemand

    113

    views

    43

    downloads

    0

    comments

    0

    adaptations

    2012-Arvind_Kumar_Misra-A simple mathematical model for the spread of two political parties
    In this paper, a non-linear mathematical model for the spread of two political parties has been proposed and analyzed by using epidemiological approach.

    Keywords: epidemiccompartmentpolitical parties

    125

    views

    47

    downloads

    0

    comments

    0

    adaptations

    1968-Wagner-Aghajanian-Bing-Correlation of performance test scores with tissue concentration of lysergic acid diethylamide
    This paper offers a two compartment model of lysergic acid diethylamide (LSD) in volunteer students and through parameter estimation models the amount of LSD in the tissue after its initial...

    Keywords: LSDcorrelation coefficientcompartment modellysergic acid diethylamideperformancetest scoretissue concentration

    280

    views

    70

    downloads

    0

    comments

    0

    adaptations

    2014-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
    To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for...

    Keywords: metabolic syndromecompartment modelcholesterolhigh blood cholesterol

    144

    views

    85

    downloads

    0

    comments

    0

    adaptations

    5-001-LSD-ModelingScenario
    We describe the use of a two compartment model of a linear system of first order linear differential equations to model lysergic acid diethylamide (LSD) in the body. We provide the data from the...

    Keywords: LSDSpanishcompartmentpharmacokineticslysergic acid diethylamide

    1176

    views

    5479

    downloads

    0

    comments

    0

    adaptations

    2015-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
    To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for...

    Keywords: metabolic syndromecholesterolhigh blood cholesterolcholesterol homeostasis

    129

    views

    73

    downloads

    0

    comments

    0

    adaptations

    Pharmacokinetics
    This Excel module explores how drugs are processed and absorbed in the human body.

    Keywords: drug metabolismpharmacokinetics

    86

    views

    52

    downloads

    0

    comments

    0

    adaptations

    2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
    This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.

    Keywords: absorptioncompartmentbloodstreamplasmapharmacokineticsdrugpharmacodynamics

    132

    views

    55

    downloads

    0

    comments

    0

    adaptations

    2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
    This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.

    Keywords: absorptioncompartmentbloodstreamplasmapharmacokineticspharmacodynamicstherapeutic concentration rangedrug dispositiondrug response

    140

    views

    79

    downloads

    0

    comments

    0

    adaptations

    1999-PS_Crooke-S_Hota_JJ_Martini-JR_Hochkiss-A Mathematical Model for Carbon Dioxide Exchange
    A mathematical model is presented to study the effect of Tracheal Gas Insufflation (TGI) on the alveolar ventilation during passive, mechanical ventilation.

    Keywords: mechanical ventilationventilationcarbon dioxide exchangetracheal gas insufflationalveolar ventilationshunttwo-compartment model

    122

    views

    36

    downloads

    0

    comments

    0

    adaptations

    1996-D_Erdman-MM_Morelock-A Study of Kinetics
    This paper introduces new and old features of the SAS System for the estimation and simulation of systems of first-order differential equations with emphasis on examples in kinetics.

    Keywords: simulationkineticsparameter estimationEnzymesubstratesavingscompartmentstomachbloodginseng

    183

    views

    74

    downloads

    0

    comments

    0

    adaptations

    1-086-MedicinalPill-ModelingScenario
    Administration of a medicinal pill in single and multiple doses is modeled.

    Keywords: medicinespillovercompartmentbloodstreamGIT-Track

    289

    views

    225

    downloads

    0

    comments

    0

    adaptations

    1975-Rodda-Sampson-Smith-The One-Compartment Open Model Parameter Estimation
    A new estimation procedure is proposed for estimating the parameters of the simplest pharmacokinetic model, the one-compartment open model.

    Keywords: compartment modelpharmacokineticsnonlinear estimationone compartment model

    147

    views

    55

    downloads

    0

    comments

    0

    adaptations

    1-132-DigoxinElimination-ModelingScenario
    We model the concentration of digoxin eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the study...

    Keywords: nullclinespharmacokineticsdigoxindrug eliminationtwo compartment

    336

    views

    537

    downloads

    0

    comments

    0

    adaptations

    2004-Aldo_Rescigno-On the use of pharmacokinetic models
    In this paper I will define in a simple and logical way a set of useful pharmacokinetic parameters and show how their estimation depends on the assumed model.

    Keywords: compartmentsteady statepharmacokineticsvolume distribution

    119

    views

    51

    downloads

    0

    comments

    0

    adaptations

    5-020-ParacetamolAbsorption-ModelingScenario
    We offer drug absorption data on paracetamol, an analgesic pain reliever, for two different sets of patients, vegetarian and non-vegetarian. Students build a two compartment model for plasma and...

    Keywords: paracetamolanalgesicvegetariannon-vegetarian

    207

    views

    236

    downloads

    0

    comments

    0

    adaptations

    2019-Banuelos_Danet_Flores_Ramos-Epidemiological_Math_Model_Approach_To_Political_System_with_Three_Parties
    A nonlinear compartmental model is derived to study the movement between classes of voters with the assumption of a constant population that is homogeneously mixed.

    Keywords: politicsparametersvotingcompartment modelepidemiological modelequilibriathree-party system

    134

    views

    47

    downloads

    0

    comments

    0

    adaptations

    2000-Erdman-Morelock-A Study of Kinetics The Estimation and Simulation of Systems of First-Order Differential Equations
    This paper introduces new and old features of the SAS System for the estimation and simulation of systems of first-order differential equations with emphasis on examples in kinetics.

    Keywords: kineticsSAScompartmentpharmacokinetics

    1248

    views

    47

    downloads

    0

    comments

    0

    adaptations

    Close

    Home

    Search