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    Connecting Viral Pandemics to Ecological Population Growth Models
    In this activity students use the HHMI Population Growth Models interactive to explore R0 for diseases and discuss the importance of connecting population ecology to current events like the...
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    Using Linear Regression to Explore Environmental Factors Affecting Vector-borne Diseases
    In this activity students will use linear regression to analyze real data on vector-borne diseases and explore how environmental factors such as climate change or population density influence the...

    Keywords: ecologygraphingmicrobiologyqbccUnderstanding ratesCreate graphsInterpret graphsinterpret tablesConcepts in Statistics

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    Drugging SARS-CoV-2
    This case study leads students through the process of proposing a drug for a novel protein. The Mpro protease of SARS-CoV-2 is explored in detail within the PDB. Aligns with first semester...

    Keywords: viruscoronavirusPDBSARS-CoV-2proteasedrug design

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    Investigating the Ecology of Mosquitoes and Birds in Hawaii
    Examining biotic and abiotic environmental factors explain the historic, present, and future prevalence and range of avian malaria in Hawaii. The activity also asks how this affects local...

    Keywords: data analysisintroductory biologyInvasive SpeciesbirdsHawaii County

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    2014-Murillo-EtAl-Vertical Transmission in a Two-Strain Model of Dengue Fever
    The model is used to show that lower transmission rates of DENV-2 Asian are sufficient for displacing DENV-2 American in the presence of vertical transmission.

    Keywords: Peruvector-host modeldengueepidemmiologyvertical transmission

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    2020-Ciaroshi-How_COVID-19_Spreads_MathModels
    On December 31, 2019, the Chinese city of Wuhan reported an outbreak of a novel coronavirus (COVID-19) that has since killed over 4,200 people. As of March 11, 2020, over 118,000 infections—have...

    Keywords: diseasecovidoutbreakWuhancoronoavirus

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    6-015-CombatingEbolaEpidemic-ModelingScenario
    This project offers students a chance to make a policy recommendation based on analysis of a nonlinear system of differential equations (disease model). The scenario is taken from the fall of 2014...

    Keywords: diseaseEbolaAnalysisPolicydecision

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    Using Linear Regression Adaptation: Exploring Vector-borne diseases in an online classroom
    In this adaptation students in online classrooms will use linear regression at home and in synchronous online time to analyze real data on vector-borne diseases and explore how environmental...

    Keywords: ecologygraphingmicrobiologyqbccUnderstanding ratesCreate graphsInterpret graphsinterpret tablesConcepts in Statistics

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    Inquiry-based hypothesis testing using phylogenetic trees in MEGA
    A key learning objective in biology is applying bioinformatics tools to test a real-life question. These inquiry-based modules have students assemble and align data, and construct simple...

    Keywords: phylogeneticsbioinformaticsFASTANCBIBLASTmultiple sequence alignmentsequence similarityCourseSourceZika virusMEGAalcohol metabolism

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    Infectious Chocolate Joy with a Side of Poissonian Statistics: An activity connecting life science students with subtle physics concepts
    Lesson on what it means for biological processes to be Poissonian, published in CourseSource

    Keywords: quantitative biologybioinformaticsmicrobiologyphysicsNIBLSEHIVCourseSourcemultiplicity of infectionPoisson Distribution

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    2017-Fred_Adler-Mathematically Modeling Asthma
    Our Asthma models have examined how a viral infection can tip the immune system into a different state, with the potential to predispose an individual to future asthma

    Keywords: infectionasthmaimmune responserhinovirus

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    6-003-SchoolFluEpidemic-ModelingScenario
    We offer a model of the spread of flu in a school dormitory and are asked to find when the flu levels reach their peak and explain long term behavior of the spread of the flu.

    Keywords: infectionepidemicSIR modelflupeakschool children

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    The Correlation Between SARS-CoV-2 RNA in Wastewater and Rising COVID-19 Vaccination Rates, in Los Angeles California
    The COVID-19 pandemic has undoubtedly impacted everyone around the globe. In 2020, many countries entered into a lockdown, transforming daily lifestyles into isolation. The SARS-CoV-2...

    Keywords: RNASARS-CoV-2wastewater

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    Sequence Similarity: Introducing Biological Databases to Community College Biology Students
    This laboratory module, published on CourseSource, leads introductory biology students in the exploration of a basic set of bioinformatics concepts and tools.

    Keywords: phylogeneticsbioinformaticssequencingFASTANCBINIBLSEalgorithmsincubatorsBLASTmultiple sequence alignmentsequence similarityBLOSUM scoring matrixneighbor-joining distance matrixCourseSourcephylogramZika virus

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    Investigating Evidence for Climate Change (Project EDDIE)
    This multi-part activity allows students to discover the relationships between CO2 and temperature and how these variables have changed over time using real-world data.

    Keywords: Excelclimate changeGlobal Temperature Changeco2ice core data

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    Sequence Similarity: An inquiry based and "under the hood" approach for incorporating molecular sequence alignment in introductory undergraduate biology courses
    This laboratory module, published on CourseSource, leads introductory biology students in the exploration of a basic set of bioinformatics concepts and tools.

    Keywords: phylogeneticsbioinformaticssequencingFASTANCBINIBLSEalgorithmsincubatorsBLASTmultiple sequence alignmentsequence similarityBLOSUM scoring matrixneighbor-joining distance matrixCourseSourcephylogramZika virus

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    A 360˚ View of COVID-19
    In March 2020, institutions underwent a massive transition to distance learning as a result of the COVID-19 pandemic. With so little time to devise new materials to maximize learning in the new...

    Keywords: geneticsImmunologyBiochemistrybioinformaticsmolecular evolutionpublic healthvirusCOVID19

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    Forensic Phylogenetics: Implementing Tree-thinking in a Court of Law
    Here we describe an in-class activity developed for Evolutionary Biology and Biodiversity (BioEE1780) at Cornell University, an introductory course required of all biology majors. This activity...

    Keywords: phylogeneticsTree thinkingparaphyly

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    Statistics with epidemiology of COVID-19
    Introduction into heat maps, non-parametric t-test and GIF (optional) in R using an original dataset on COVID-19 infections from different counties of New Jersey, USA. Suitable for students who...

    Keywords: Rundergraduate educationheat mapsCOVID19coronavirusSARS-CoV-2GIF

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    Mock Drug Activity Enhances Student Learning About the Challenges of HIV/AIDS Therapy
    While traditional didactic coursework is important for learning about the scientific aspects of HIV/AIDS, it is difficult to convey social aspects of the epidemic. Due to effective drug therapies,...

    Keywords: drug resistanceRetrovirusViral replication

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