| 1 | <p>The Click & Learn presents different types of genes that, when mutated, contribute to cancer, including oncogenes, tumor suppressor genes, and DNA repair genes. It then explores one tumor suppressor gene, <em>p53</em>, and its role in cancer in more depth. Students learn about the structure of the protein encoded by <em>p53</em> and how it normally functions to regulate cell division.</p>
| 1 | <p><b id="docs-internal-guid-40072766-7fff-d02c-345e-91bcecd39cab">Students approach this activity in a flipped classroom model. They will complete the p53 Gene and Cancer Click and Learn from HHMI Biointeractives along with an interactive power point about cell signaling. In order to ensure that students have completed the pre-class material they will take an online quiz before class. In class students will work together in small groups to go over the worksheet of questions relating to the Role of p53 in the Cell Cycle Data Point activity from HHMI Biointeractive. The click and learn and power point helps to give student background information on both cell signaling and the cell cycle. The data point activity helps students to integrate that knowledge with data analysis and interpretation. In the data point activity students analyze and interpret data, develop a hypothesis and develop follow up studies based on data. </b></p>
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