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C1. Explain the role of computation and data mining in addressing hypothesis-driven and hypothesis-generating questions within the life sciences. Life sciences students should have a clear understanding of the role computing and data mining play in modern biology. Given a traditional hypothesis-driven research question, students should have ideas about what types of data and software exist that could help them answer the question quickly and efficiently. They should also appreciate that mining large datasets can generate novel hypotheses to be tested in the lab or field.

  • Compare and contrast computer-based research with wet-lab research.
  • Explain the role of computation in finding genes, detecting the function of protein domains, and inferring protein function.
  • Describe the role of various databases in identifying potential gene targets for drug development.

Resources (21-25 of 25)

  1. Using Synthetic Biology to Teach Data Science

    26 Jun 2019 | Teaching Materials | Contributor(s):

    By Margaret S Saha1, Beteel Abu-Ageel1, Sanjana Challa1, Xiangyi Fang1, Chai Hibbert1, Anna Isler1, Elias Nafziger1, Adam Oliver1, Hanqiu Peng1, Julia Urban1, Vivian Zhu1

    College of William and Mary

    Abstract for poster on using synthetic biology to introduce students to meaningful data mining, analysis, and application to engineering novel biological constructs.

    https://qubeshub.org/publications/1326/?v=1

  2. Using Undergraduate Molecular Biology Labs to Discover Targets of miRNAs in Humans

    04 Jan 2019 | Teaching Materials | Contributor(s):

    By Adam Idica1, Jordan Thompson1, Irene Munk Pedersen1, Pavan Kadandale1

    University of California, Irvine

    In this lesson, we describe an easily adaptable lab module that can be used in existing undergraduate molecular biology lab courses to conduct authentic scientific research, published in CourseSource

    https://qubeshub.org/publications/1007/?v=1

  3. Wolf Sheep Predation Simulation Exercise

    05 Jun 2017 | Teaching Materials | Contributor(s):

    By Liz Ryder

    Worcester Polytechnic Institute

    This resource is an exercise to introduce students to agent-based modeling of biological systems through working with a simple existing model.

    https://qubeshub.org/publications/29/?v=2

  4. Wolf Sheep Predation Simulation Exercise

    03 Aug 2016 | Teaching Materials | Contributor(s):

    By Liz Ryder

    Worcester Polytechnic Institute

    This resource is an exercise to introduce students to agent-based modeling of biological systems through working with a simple existing model.

    https://qubeshub.org/publications/29/?v=1

  5. Yeti or not: Do they exist?

    31 Dec 2020 | Teaching Materials | Contributor(s):

    By Keith Johnson1, Adam Kleinschmit2, Jill Rulfs3, William (Bill) Morgan4

    1. Bradley University College of Liberal Arts and Sciences 2. University of Dubuque 3. Worcester Polytechnic Institute 4. The College of Wooster

    Through this 4-part bioinformatics case study, students will be led through the forensic analysis of putative Yeti artifacts based on published findings.

    https://qubeshub.org/publications/1832/?v=3

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