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Maria vs Malaria - AR Adaptation
04 Nov 2023 | Teaching Materials | Contributor(s):
By Didem Vardar-Ulu1, Saif Eldeen Ragab1, Swati Agrawal2
1. Boston University, Chemistry Department 2. University of Mary Washington
This case study focuses on a specific enzyme Lactate Dehydrogenase (LDH) in the malarial parasite as a target for treating malaria. Students will be able to view selected molecular views from the...
https://qubeshub.org/publications/4554/?v=1
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Maria vs Malaria
02 Nov 2023 | Teaching Materials | Contributor(s):
By Didem Vardar-Ulu1, Serena Yu1, Alicia Lau1, Molly Szpakowski1
Boston University
This case study focuses on a specific enzyme Lactate Dehydrogenase (LDH) in the malarial parasite as a target for treating malaria.
https://qubeshub.org/publications/4551/?v=1
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Ecology/Environmental Biology Molecular Case Studies for Molecular CaseNet - YouTube
06 Dec 2021 | Teaching Materials | Contributor(s):
By Debra Linton1, Heather Simpson2, Jennifer Glee Buntz2, Sheela Vemu3, Shuchismita Dutta4
1. Central Michigan University 2. Central New Mexico Community College 3. Waubonsee Community College - Tenure Track and Northern Illinois University 4. RCSB Protein Data Bank, Rutgers University
Biome Institute 2021, Fall Working Group Summary Video
https://qubeshub.org/publications/2816/?v=1
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Mol* Adaptation: Case of Severe Insulin Resistance
23 Jul 2021 | Teaching Materials | Contributor(s):
By Keith A. Johnson
Bradley University College of Liberal Arts and Sciences
This is an adaptation using Mol* on the original case written. This case focuses on understanding how a mutation in a cell signalling protein (a kinase) can prevent insulin function and lead to...
https://qubeshub.org/publications/2483/?v=1
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Students Authoring Molecular Case Studies
22 Jul 2021 | Teaching Materials | Contributor(s):
By Elizabeth Pollock1, Kasandra Riley (She/Her)2, Didem Vardar-Ulu3, Shuchismita Dutta4
1. Stockton University 2. Rollins College 3. Boston University, Chemistry Department 4. RCSB Protein Data Bank, Rutgers University
Poster on using case studies to help students develop their skills in reading primary literature and identifying authentic scientific problems by authoring their own case studies. Presented at the...
https://qubeshub.org/publications/2466/?v=1
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Happy Blue Baby
09 Jun 2021 | Teaching Materials | Contributor(s):
By Didem Vardar-Ulu
Boston University, Chemistry Department
This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved on its own...
https://qubeshub.org/publications/2419/?v=1
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COVID-19: Molecular Basis Infection Revisited One Year into the Pandemic
09 Jun 2021 | Teaching Materials | Contributor(s):
By Didem Vardar-Ulu
Boston University, Chemistry Department
This adaptation was written in Spring 2021 exactly one year after the original case and includes explorations of the emerging mutations within the spike protein
https://qubeshub.org/publications/2424/?v=1
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Waking up Anna - Adaptations and Conversion to Mol*
08 Jun 2021 | Teaching Materials | Contributor(s):
By Keith A. Johnson
Bradley University College of Liberal Arts and Sciences
This case focuses on understanding the molecular basis of Anna's sleeping disorder and its treatment.The adaptations addressed question clarity and reformatting to use Mol*.
https://qubeshub.org/publications/2420/?v=1
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Hemoglobin bioinformatics
07 Jun 2021 | Teaching Materials | Contributor(s):
By Keith A. Johnson
Bradley University College of Liberal Arts and Sciences
This is an introduction to bioinformatics using hemoglobin as an example. The worksheets introduce students to resources to explore the DNA, RNA and polypeptide linear structure with a brief...
https://qubeshub.org/publications/2416/?v=1
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Happy Blue Baby: MCQs for large classes
18 May 2021 | Teaching Materials | Contributor(s):
By "KP" Kristen Procko
The University of Texas at Austin
Multiple choice questions for the Happy Blue Baby case study pre-work
https://qubeshub.org/publications/2381/?v=1
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Molecular CaseNet - Developing Intro Tutorials - YouTube
03 Dec 2020 | Teaching Materials | Contributor(s):
By Jean Cardinale1, Keith A. Johnson2, Marie C. Montes-Matias3, Natalie Stringer4, Aeisha Thomas5, Shuchismita Dutta6
1. Alfred University 2. Bradley University College of Liberal Arts and Sciences 3. Union County College 4. LabArchives, LLC 5. Crown College 6. RCSB Protein Data Bank, Rutgers University
Biome Institute 2020, Summary Video
https://qubeshub.org/publications/2157/?v=1
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Molecular CaseNet - Students Writing Cases - YouTube
03 Dec 2020 | Teaching Materials | Contributor(s):
By Didem Vardar-Ulu1, Elizabeth Pollock2, Kasandra Riley (She/Her)3, Nik Tsotakos4, Swati Agrawal5, Shuchismita Dutta6
1. Boston University, Chemistry Department 2. Stockton University 3. Rollins College 4. Penn State Harrisburg 5. University of Mary Washington 6. RCSB Protein Data Bank, Rutgers University
Biome Institute 2020, Summary Video
https://qubeshub.org/publications/2158/?v=1
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CRISPR Gene Editing: Designing the gRNA and Donor Template
15 Jul 2020 | Teaching Materials | Contributor(s):
By Laurel Lorenz
Princeton
In this adaptation, students learn how CRISPR/Cas9 is used in bacterial immunity and gene editing. Students create both a gRNA target and a donor template to edit a gene. Mutations can be from the...
https://qubeshub.org/publications/1962/?v=1
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Sickle Cell Anemia using Nicholas’ Story
25 Jun 2020 | Teaching Materials | Contributor(s):
By Sharon Cisneros
Malcolm X College
The goal of this exercise is to introduce students to 3-D structures of biological molecules, visualize and manipulate them to understand their functions. The exercise also helps them see the...
https://qubeshub.org/publications/1943/?v=1
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COVID-19: Molecular Basis of Infection-ADAPTATION
17 Jun 2020 | Teaching Materials | Contributor(s):
By Didem Vardar-Ulu
Boston University, Chemistry Department
This case was written in Spring 2020 during the COVID-19 pandemic. It focuses on understanding the structure and interaction of the SARS-Cov-2 viral spike protein that facilitates infection in...
https://qubeshub.org/publications/1936/?v=1
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Molecular Basis of Sickle Cell Disease
15 Jun 2020 | Teaching Materials | Contributor(s):
By Didem Vardar-Ulu
Boston University, Chemistry Department
This multi part case on hemoglobin structure as it relates to oxygen binding and sickle cell disease focuses on utilizing bioinformatics and molecular visualization tools to learn about the sickle...
https://qubeshub.org/publications/1925/?v=1
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The Happy Blue Baby Hemoglobin
14 Jun 2020 | Teaching Materials | Contributor(s):
By Kasandra Jean-Louise Riley1, Shuchismita Dutta2
1. Rollins College 2. RCSB Protein Data Bank, Rutgers University
This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved.
https://qubeshub.org/publications/1924/?v=1
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Nicholas' Story
13 Jun 2020 | Teaching Materials | Contributor(s):
By Nik Tsotakos
Penn State Harrisburg
This 3 part case on sickle cell disease focuses on visualizing and understanding the molecular basis of its cause, symptoms, complications, management, treatment, and possible cures.
https://qubeshub.org/publications/1919/?v=1
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COVID-19: Molecular Basis of Infection
12 Jun 2020 | Teaching Materials | Contributor(s):
By Didem Vardar-Ulu1, Shuchismita Dutta2
1. Boston University 2. RCSB Protein Data Bank, Rutgers University
This case was written in Spring 2020 during the COVID-19 pandemic. It focuses on understanding the structure and interaction of the SARS-Cov-2 viral spike protein that facilitates infection in...
https://qubeshub.org/publications/1912/?v=1
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A Case of Severe Insulin Resistance
12 Jun 2020 | Teaching Materials | Contributor(s):
By Melanie Lenahan1, Shuchismita Dutta2
1. Raritan Valley Community College 2. RCSB Protein Data Bank, Rutgers University
This case focuses on understanding how a mutation in a cell signalling protein (a kinase) can prevent insulin function and lead to diabetes.
https://qubeshub.org/publications/1911/?v=1