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Teaching Materials (1-20 of 25)

  1. A Case of Severe Insulin Resistance

    12 Jun 2020 | Teaching Materials | Contributor(s):

    By Melanie Lenahan1, Shuchismita Dutta2

    1. Raritan Valley Community College 2. RCSB Protein Data Bank, Rutgers University

    This case focuses on understanding how a mutation in a cell signalling protein (a kinase) can prevent insulin function and lead to diabetes.

    https://qubeshub.org/publications/1911/?v=1

  2. COVID-19: Molecular Basis Infection Revisited One Year into the Pandemic

    09 Jun 2021 | Teaching Materials | Contributor(s):

    By Didem Vardar-Ulu

    Boston University, Chemistry Department

    This adaptation was written in Spring 2021 exactly one year after the original case and includes explorations of the emerging mutations within the spike protein

    https://qubeshub.org/publications/2424/?v=1

  3. COVID-19: Molecular Basis of Infection

    12 Jun 2020 | Teaching Materials | Contributor(s):

    By Didem Vardar-Ulu1, Shuchismita Dutta2

    1. Boston University 2. RCSB Protein Data Bank, Rutgers University

    This case was written in Spring 2020 during the COVID-19 pandemic. It focuses on understanding the structure and interaction of the SARS-Cov-2 viral spike protein that facilitates infection in...

    https://qubeshub.org/publications/1912/?v=1

  4. COVID-19: Molecular Basis of Infection-ADAPTATION

    17 Jun 2020 | Teaching Materials | Contributor(s):

    By Didem Vardar-Ulu

    Boston University, Chemistry Department

    This case was written in Spring 2020 during the COVID-19 pandemic. It focuses on understanding the structure and interaction of the SARS-Cov-2 viral spike protein that facilitates infection in...

    https://qubeshub.org/publications/1936/?v=1

  5. CRISPR Gene Editing: Designing the gRNA and Donor Template

    15 Jul 2020 | Teaching Materials | Contributor(s):

    By Laurel Lorenz

    Princeton

    In this adaptation, students learn how CRISPR/Cas9 is used in bacterial immunity and gene editing. Students create both a gRNA target and a donor template to edit a gene. Mutations can be from the...

    https://qubeshub.org/publications/1962/?v=1

  6. Ecology/Environmental Biology Molecular Case Studies for Molecular CaseNet - YouTube

    06 Dec 2021 | Teaching Materials | Contributor(s):

    By Debra Linton1, Heather Simpson2, Jennifer Glee Buntz2, Sheela Vemu3, Shuchismita Dutta4

    1. Central Michigan University 2. Central New Mexico Community College 3. Waubonsee Community College - Tenure Track and Northern Illinois University 4. RCSB Protein Data Bank, Rutgers University

    Biome Institute 2021, Fall Working Group Summary Video

    https://qubeshub.org/publications/2816/?v=1

  7. Evolution of Caffeine Biosynthesis Enzymes

    12 Jun 2020 | Teaching Materials | Contributor(s):

    By Brian Sullivan1, Shuchismita Dutta2

    1. University of North Carolina 2. RCSB Protein Data Bank, Rutgers University

    This case focuses on exploring why plants make secondary metabolites like caffeine and how the enzymes required for making caffeine evolved.

    https://qubeshub.org/publications/1909/?v=1

  8. Happy Blue Baby

    09 Jun 2021 | Teaching Materials | Contributor(s):

    By Didem Vardar-Ulu

    Boston University, Chemistry Department

    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved on its own...

    https://qubeshub.org/publications/2419/?v=1

  9. Happy Blue Baby

    11 Jun 2020 | Teaching Materials | Contributor(s):

    By Shuchismita Dutta

    RCSB Protein Data Bank, Rutgers University

    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved on its own...

    https://qubeshub.org/publications/1902/?v=1

  10. Happy Blue Baby: MCQs for large classes

    18 May 2021 | Teaching Materials | Contributor(s):

    By "KP" Kristen Procko

    The University of Texas at Austin

    Multiple choice questions for the Happy Blue Baby case study pre-work

    https://qubeshub.org/publications/2381/?v=1

  11. Hemoglobin bioinformatics

    07 Jun 2021 | Teaching Materials | Contributor(s):

    By Keith A. Johnson

    Bradley University College of Liberal Arts and Sciences

    This is an introduction to bioinformatics using hemoglobin as an example. The worksheets introduce students to resources to explore the DNA, RNA and polypeptide linear structure with a brief...

    https://qubeshub.org/publications/2416/?v=1

  12. Maria vs Malaria

    02 Nov 2023 | Teaching Materials | Contributor(s):

    By Didem Vardar-Ulu1, Serena Yu1, Alicia Lau1, Molly Szpakowski1

    Boston University

    This case study focuses on a specific enzyme Lactate Dehydrogenase (LDH) in the malarial parasite as a target for treating malaria.

    https://qubeshub.org/publications/4551/?v=1

  13. Maria vs Malaria - AR Adaptation

    04 Nov 2023 | Teaching Materials | Contributor(s):

    By Didem Vardar-Ulu1, Saif Eldeen Ragab1, Swati Agrawal2

    1. Boston University, Chemistry Department 2. University of Mary Washington

    This case study focuses on a specific enzyme Lactate Dehydrogenase (LDH) in the malarial parasite as a target for treating malaria. Students will be able to view selected molecular views from the...

    https://qubeshub.org/publications/4554/?v=1

  14. Mol* Adaptation: Case of Severe Insulin Resistance

    23 Jul 2021 | Teaching Materials | Contributor(s):

    By Keith A. Johnson

    Bradley University College of Liberal Arts and Sciences

    This is an adaptation using Mol* on the original case written. This case focuses on understanding how a mutation in a cell signalling protein (a kinase) can prevent insulin function and lead to...

    https://qubeshub.org/publications/2483/?v=1

  15. Molecular Basis of Sickle Cell Disease

    15 Jun 2020 | Teaching Materials | Contributor(s):

    By Didem Vardar-Ulu

    Boston University, Chemistry Department

    This multi part case on hemoglobin structure as it relates to oxygen binding and sickle cell disease focuses on utilizing bioinformatics and molecular visualization tools to learn about the sickle...

    https://qubeshub.org/publications/1925/?v=1

  16. Molecular CaseNet - Developing Intro Tutorials - YouTube

    03 Dec 2020 | Teaching Materials | Contributor(s):

    By Jean Cardinale1, Keith A. Johnson2, Marie C. Montes-Matias3, Natalie Stringer4, Aeisha Thomas5, Shuchismita Dutta6

    1. Alfred University 2. Bradley University College of Liberal Arts and Sciences 3. Union County College 4. LabArchives, LLC 5. Crown College 6. RCSB Protein Data Bank, Rutgers University

    Biome Institute 2020, Summary Video

    https://qubeshub.org/publications/2157/?v=1

  17. Molecular CaseNet - Students Writing Cases - YouTube

    03 Dec 2020 | Teaching Materials | Contributor(s):

    By Didem Vardar-Ulu1, Elizabeth Pollock2, Kasandra Riley (She/Her)3, Nik Tsotakos4, Swati Agrawal5, Shuchismita Dutta6

    1. Boston University, Chemistry Department 2. Stockton University 3. Rollins College 4. Penn State Harrisburg 5. University of Mary Washington 6. RCSB Protein Data Bank, Rutgers University

    Biome Institute 2020, Summary Video

    https://qubeshub.org/publications/2158/?v=1

  18. Nicholas' Story

    13 Jun 2020 | Teaching Materials | Contributor(s):

    By Nik Tsotakos

    Penn State Harrisburg

    This 3 part case on sickle cell disease focuses on visualizing and understanding the molecular basis of its cause, symptoms, complications, management, treatment, and possible cures.

    https://qubeshub.org/publications/1919/?v=1

  19. Nicholas' Story

    11 Jun 2020 | Teaching Materials | Contributor(s):

    By Shuchismita Dutta1, Kimberly Linenberger Cortes2, Henry Vincent Jakubowski3, Melanie Lenahan4, David Marcey5, Pat Marsteller6, Cassidy Terrell7

    1. RCSB Protein Data Bank, Rutgers University 2. Kennesaw State University 3. College of Saint Benedict/Saint John's University 4. Raritan Valley Community College 5. California Lutherian University 6. Emory University 7. University of Minnesota, Rocester

    This 3 part case on sickle cell disease focuses on visualizing and understanding the molecular basis of its cause, symptoms, complications, management, treatment, and possible cures.

    https://qubeshub.org/publications/1907/?v=1

  20. Piwi Matters

    12 Jun 2020 | Teaching Materials | Contributor(s):

    By Laurel Lorenz1, Shuchismita Dutta2

    1. Princeton University 2. RCSB Protein Data Bank, Rutgers University

    This case focuses on understanding structure and function relationships in Piwi, a protein that is critical for germline stem cell function and development of eggs in the fruit fly ovary.

    https://qubeshub.org/publications/1910/?v=1

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