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Synthetic Organisms Simplify Biology

Review article from 2019

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Lisa Scheifele onto Creating synthetic genomes

A semi-synthetic organism that stores and retrieves increased genetic information

Creation of a semi-synthetic organism whose DNA harbours two additional letters that form a third, unnatural base pair.

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Lisa Scheifele onto Creating synthetic genomes

Genome-wide inactivation of Retroviruses

Demonstration of inactivation of porcine endogenous retroviruses using CRISPR technology to enable porcine-to-human xenotransplantation of organs.

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Lisa Scheifele onto Creating synthetic genomes

Engineering bacteria for diagnostic and therapeutic applications

A review article on designing bacteria for diagnostics and therapeutics

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Lisa Scheifele onto Creating synthetic genomes

Total synthesis of Escherichia coli with a recoded genome

A synthetic E. coli genome that has been designed to use only 61 of the 64 available codons. Includes webinar from Genewiz on design and assembly of the genome.

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Lisa Scheifele onto Creating synthetic genomes

Technological challenges and milestones for writing genomes

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Lisa Scheifele onto Creating synthetic genomes

Synthetic Generation of Influenza Vaccine Viruses for Rapid Response to Pandemics

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Lisa Scheifele onto Creating synthetic genomes