A "Box of Lessons" for Exploring Biomolecular Structure and Function
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20 Jul 2022 | Contributor(s): Keith A. Johnson, Alexandra Pettit, Sheela Vemu, Shuchismita Dutta | doi:10.25334/K480-QR38
Biomolecular structure and function is emphasized as a core concept in a variety of community determined educational standards for biology and chemistry. Most curricula introduce students to the building blocks and principles of biomolecular structures, in introductory chapters of biology,...
Nextstrain adaptations for Understanding COVID-19
20 Aug 2021 | Contributor(s): Keith A. Johnson | doi:10.25334/7AZA-5T38
This resource introduces students to the use of Nextstrain and Nextclade to visualize the phylogeny of SARS-CoV-2 variants of concern and variants of interest. Terminology and an introduction to the Nextclade resource are provided in a 4-part worksheet.
Mol* Adaptation: Case of Severe Insulin Resistance
23 Jul 2021 | Contributor(s): Keith A. Johnson | doi:10.25334/FW9S-2G51
This is an adaptation using Mol* on the original case written. This case focuses on understanding how a mutation in a cell signalling protein (a kinase) can prevent insulin function and lead to diabetes.
Waking up Anna - Adaptations and Conversion to Mol*
08 Jun 2021 | Contributor(s): Keith A. Johnson | doi:10.25334/T9X9-K122
This case focuses on understanding the molecular basis of Anna's sleeping disorder and its treatment. The adaptations addressed question clarity and reformatting to use Mol*.
Hemoglobin bioinformatics
07 Jun 2021 | Contributor(s): Keith A. Johnson | doi:10.25334/MMEY-8321
This is an introduction to bioinformatics using hemoglobin as an example. The worksheets introduce students to resources to explore the DNA, RNA and polypeptide linear structure with a brief introduction to the quaternary structure of hemoglobin.
Macromolecular math
24 May 2021 | Contributor(s): Keith A. Johnson | doi:10.25334/SY28-W488
This worksheet was developed for use in an introductory biology course to review the chemical bonds and structure of biological macromolecules. A nutritional label is provided to illustrate that we consume macromolecules in our foods.
Yeti or not: Do they exist?
31 Dec 2020 | Contributor(s): Keith Johnson, Adam Kleinschmit, Jill Rulfs, William (Bill) Morgan | doi:10.25334/GDSW-P773
Through this 4-part bioinformatics case study, students will be led through the forensic analysis of putative Yeti artifacts based on published findings.
Molecular CaseNet - Developing Intro Tutorials - YouTube
03 Dec 2020 | Contributor(s): Jean Cardinale, Keith A. Johnson, Marie C. Montes-Matias, Natalie Stringer, Aeisha Thomas, Shuchismita Dutta | doi:10.25334/7GER-QS63
Biome Institute 2020, Summary Video
Understanding COVID-19 Biology to Design a Vaccine - Ethics supplement
08 Jul 2020 | Contributor(s): Keith A. Johnson | doi:10.25334/K9GS-KJ30
The adaptation to Understanding COVID-19 Biology to Design a Vaccine entails two ethics supplements. The first supplement addresses the use of off-label drugs in the pandemic (or other situation). The second supplement addresses wet markets.
Understanding COVID-19 Biology to Design a Vaccine
12 Jun 2020 | Contributor(s): Keith Johnson, Didem Vardar-Ulu, Shuchismita Dutta | doi:10.25334/DNC7-8581
This multi-part case study introduces the reader to the SARS-CoV-2 virus, replication, and treatment. Additional worksheets introduce students to bioinformatics tools of 3-D protein visualization and BLAST searches.
14 May 2020 | Contributor(s): Keith Johnson | doi:10.25334/6QTG-RQ39
Through this 2-part bioinformatics case study, students will be led through the forensic analysis of putative Yeti artifacts based on published findings.