About

iCn3D ("I see in 3D") provides a powerful web-based tool to not also teach students at all levels about antibody structure and function but also presents a tool in which students can use to research antibody-epitope interactions.  It allows for visualization in 3D, 2D, and 1D.  Our group worked to develop methods in which iCn3D can be used in educational activities.

  • High School (NGSS aligned)/Freshman/Community College/Lower level college courses
    • Venn Diagrams to identify similar structures in various animal antibodies
    • iCn3D images showing Van der Waal interactions that are present in SARS-CoV-2 and spike protein
  • Upper level courses (possible CUREs)
    • Investigate same antibody with different epitopes attached at same location.  Using iCn3D can find common interactions in the interface and identify key amino acids. 

Team