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DNA and Knot Theory

Author(s): Lou Gross1, Monica Beals1, Susan Harrell1

University of Tennessee Knoxville

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Summary:
This module introduces knot theory in the context of understanding the packing of DNA. It is intended for an introductory biology audience.

Licensed under CC Attribution-ShareAlike 4.0 International according to these terms

Version 1.0 - published on 15 Feb 2019 doi:10.25334/Q4HM9M - cite this

Keywords

  1. DNA
  2. Genetic Information
  3. Topology
  4. Knot Theory

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Description

Student Introduction: DNA is the genetic material of all cells, containing coded information about cellular molecules and processes. DNA consists of two polynucleotide strands twisted around each other in a double helix. The first step in cellular division is to replicate DNA so that copies can be distributed to daughter cells. Additionally, DNA is involved in transcribing proteins that direct cell growth and activities. However, DNA is tightly packed into genes and chromosomes. In order for replication or transcription to take place, DNA must first unpack itself so that it can interact with enzymes.

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