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Module 5: The Need for an Open Reading Frame

By Carina Howell1, Leocadia Paliulis2, Anne Rosenwald3

1. Lock Haven University 2. Bucknell University 3. Georgetown University

In this module, students will learn to identify the open reading frames for a given gene, and define the phases of the splice donor and acceptor sites.

Listed in Teaching Materials | resource by group Genomics Education Alliance

Version 1.0 - published on 25 Jul 2020 doi:10.25334/N11Z-PK53 - cite this

Licensed under CC Attribution-ShareAlike 4.0 International according to these terms

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Description

Translation of messenger RNA is required for synthesis of proteins. Students will learn to determine the codons for specific amino acids and identify reading frames by looking at the base position track in the genome browser, to assemble exons to maintain the open reading frame (ORF) for a given gene, define the phases of the splice donor and acceptor sites and describe how they impact the maintenance of the ORF, and identify start and stop codons of an assembled ORF.

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