Module 6: Alternative Splicing
Author(s): Leocadia Paliulis1, Anne Rosenwald2
1. Bucknell University 2. Georgetown University
1314 total view(s), 2845 download(s)
Summary:
This module explores how multiple different mRNAs and polypeptides can be encoded by the same gene. After completing this module students will be able to explain how alternative splicing of a gene can lead to different mRNAs.
Contents:
- Module_6_Alternative_Splicing.docx(DOCX | 2 MB)
- Module_6_Alternative_Splicing.pdf(PDF | 2 MB)
- Module_6_Alternative_Splicing_Answer_Sheet.docx(DOCX | 44 KB)
- Module_6_Alternative_Splicing_Answer_Sheet.pdf(PDF | 28 KB)
- Module_6_Alternative_Splicing_tra.pdf(PDF | 503 KB)
- Module_6_Alternative_Splicing_tra.pptx(PPTX | 839 KB)
- Module_6_Cover_Page.docx(DOCX | 32 KB)
- Module_6_Cover_Page.pdf(PDF | 23 KB)
- Module 6: Alternative Splicing (Read The Docs Version)
- License terms
Description
Many genes have exons that can be linked together in more than one way to produce a variety of different (though related) transcripts. In this lesson, students will examine how alternative splicing of a gene can lead to different mRNAs and how alternative splicing can lead to the production of different polypeptides and result in drastic changes in phenotype.
Cite this work
Researchers should cite this work as follows:
- Paliulis, L., Rosenwald, A. (2020). Module 6: Alternative Splicing. Genomics Education Alliance, QUBES Educational Resources. doi:10.25334/B3AH-GV62