MCC - A National Malate Dehydrogenase Protein-Centric Molecular Life Sciences Couse-based Undergraduate Research Network (RCN-UBE Introduction)
Author(s): Joseph John Provost1, ellis bell1, Amy Springer2, Lisa Gentile3
1. University of San Diego 2. University of Massachusetts 3. College of St Ben's/St John University
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Description
MCC CUREs engage students in authentic research experiences in a regularly scheduled laboratory class. They are focused on the enzyme Malate Dehydrogenase, and can be taught from first year to senior year in either a full semester version or a modular format (5-6 weeks) within a semester. MCC CUREs, in addition to conforming with the CURENet definition above, share eight common elements of Research, allowing for OUR pedagogical research efforts to determine key elements of research that contribute to desired student outcomes in a CURE. i) Relevance, ii) Scientific Background, iii) Hypothesis Development, iv) Proposal, v)Experiments, Teamwork, Collaboration, vi)Reproducibility, vii) Data Analysis & Drawing Evidence Based Conclusion and viii) Presentation.
Ways to learn more:
- Bell E. The future of education in the molecular life sciences. Nat Rev Mol Cell Biol. 2001 Mar;2(3):221-5. doi: 10.1038/35056610. PMID: 11265253.
- Bell E. Using research to teach an "introduction to biological thinking". Biochem Mol Biol Educ. 2011 Jan-Feb;39(1):10-6. doi: 10.1002/bmb.20441. PMID: 21433247.
- Bell JK, Eckdahl TT, Hecht DA, Killion PJ, Latzer J, Mans TL, Provost JJ, Rakus JF, Siebrasse EA, Ellis Bell J. CUREs in biochemistry-where we are and where we should go. Biochem Mol Biol Educ. 2017 Jan 2;45(1):7-12. doi: 10.1002/bmb.20989. Epub 2016 Jun 30. PMID: 27357379; PMCID: PMC5297992.
- Bell A, Christian L, Hecht D, Huisinga K, Rakus J, Bell E. Teaching virtual protein-centric CUREs and UREs using computational tools. Biochem Mol Biol Educ. 2020 Nov;48(6):646-647. doi: 10.1002/bmb.21454. Epub 2020 Sep 12. PMID: 32919430.
- Callahan, K. P., Peterson, C. N., Martinez-Vaz, B. M., Huisinga, K. L., Galport, N., Koletar, C., ... & Bell, E. (2022). External Collaboration Results in Student Learning Gains and Positive STEM Attitudes in CUREs. CBE—Life Sciences Education, 21(4), ar74.
- Callahan, K. P., Mans, T., Zhang, J., Bell, E., & Bell, J. (2022). Using bioinformatics and molecular visualization to develop student hypotheses in a malate dehydrogenase oriented CURE.
- DeChenne-Peters, S. E., Rakus, J. F., Parente, A. D., Mans, T. L., Eddy, R., Galport, N., ... & Bell, J. K. (2023). Length of course-based undergraduate research experiences (CURE) impacts student learning and attitudinal outcomes: A study of the Malate dehydrogenase CUREs Community (MCC). Plos one, 18(3), e0282170.
Ways to get involved:
- To join the group or participate in our virtual workshops or thinktanks contact Ellis Bell or visit the MCC website or the OUR Website
RCN-UBE #2119918Cite this work
Researchers should cite this work as follows:
- Provost, J. J., bell, e., Springer, A., Gentile, L. (2023). MCC - A National Malate Dehydrogenase Protein-Centric Molecular Life Sciences Couse-based Undergraduate Research Network (RCN-UBE Introduction). RCN-UBE Community, QUBES Educational Resources. doi:10.25334/RMT7-WH32