Cellular Respiration and pH: blocking the electron transport chain and its effects on the proton gradient, pH, and ATP production
Author(s): Evdokia Kastanos1, Julie Takacs2, Shannon Dahl3, Padmavathi Tangirala4, Ben Nicholson1, Susan Warner5
1. Montgomery College/Rockville 2. Anne Arundel Community College 3. Howard Community College 4. Montgomery College/Germantown 5. Community College of Baltimore County
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- Cellular Respiration and pH_Instructor Guide_QUBES_V2.docx (Instructors only)(DOCX | 1 MB)
- Cellular Respiration_In-class Module_Student V_QUBES_V2.docx(DOCX | 697 KB)
- Cellular Respiration_Pre-Work_Student V_QUBES V2.docx(DOCX | 852 KB)
- License terms
Description
This module on cellular respiration is primarily intended for introductory biology for majors and could be completed in one hour.
Students should have prior knowledge of:
- eukaryotic cell structures, and more specifically the structure of mitochondria, as well as the concept of energy and energy transformations and the law of conservation of energy.
- the aerobic respiration pathway, its stages, and the energy molecules NADH, FADH2, and ATP.
- creating and interpreting graphs.
Prior to implementing the module, students should read the cellular respiration chapter and complete the pre-work. The instructor version of the module with keys to the pre-work and the in-class module is provided.
During the module, have students break up into groups of 2-3. The module can be provided as a printed copy or can be completed on a computer. As Cellular Respiration is conceptually a challenging topic for many students, it is critical for the instructor to circulate and assist. Students need more assistance with predicting the effect of electron transport blockers on energy production. Graphs can be drawn on the printed copy or on excel if the module is done on a computer.
This module was developed and implemented as part of the NEXUS Institute for Quantitative Biology (NIQB), which is a collaborative project funded by the National Science Foundation's Improving Undergraduate STEM Education (NSF-IUSE) initiative. NIQB is a collaboration between University of Maryland, Baltimore County (DUE-1821274), Anne Arundel Community College (DUE-1821179), Community College of Baltimore County (DUE-1821249), Howard Community College (DUE-1820903), and Montgomery College (DUE-1821169).
Cite this work
Researchers should cite this work as follows:
- Kastanos, E., Takacs, J., Dahl, S., Tangirala, P., Nicholson, B., Warner, S. (2023). Cellular Respiration and pH: blocking the electron transport chain and its effects on the proton gradient, pH, and ATP production. NEXUS Institute for Quantitative Biology (NIQB), QUBES Educational Resources. doi:10.25334/AWRM-2T59