In this activity, students will learn about behavioral and immunological responses to a bacterial infection. The activity emphasized the host’s responses rather than bacterial manipulation of the host. In the activity, students will apply core concepts and competencies from Vision & Change (https://visionandchange.org/). The activity uses a hands-on data analysis approach for completing an assignment, either in class or as homework. At the end of this activity, students write up a lab report and/or answer questions related to the activity. The “in class” part of the study was designed to be completed in a 3-hour period.