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Assessment: When tests disagree, how do I know if I have COVID-19?

Author(s): Holly Basta1, Iglika Pavlova2, Aparna Shah3, Archana Lal4, Sean Coleman5

1. Rocky Mountain College 2. Michigan State University 3. Virginia Tech 4. Labette Community College 5. Wartburg College

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Summary:
In this activity, students learned about the immune response to infection by exploring different types of tests—PCR, antigen, and antibody tests—to detect SARS-CoV-2 viral genetic material, antigens, or anti-SARS-CoV-2 antibodies. Students applied…

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In this activity, students learned about the immune response to infection by exploring different types of tests—PCR, antigen, and antibody tests—to detect SARS-CoV-2 viral genetic material, antigens, or anti-SARS-CoV-2 antibodies. Students applied core concepts and competencies from Vision & Change (https://visionandchange.org/). The activity followed a jigsaw format, where students selected one of three specialties (epidemiologist, infectious disease doctor, or immunologist) and completed an assignment, either in-class or as homework, based on their chosen specialty. Preliminary data from a single-institution implementation showed a statistically significant increase in total scores and in 2 out of 5 test questions on a concept-based test after completing the activity. On a Likert scale, students reported that the background information provided was sufficient and engaging. These results will inform future iterations of this activity.

Licensed under CC Attribution-NonCommercial-ShareAlike 4.0 International according to these terms

Version 1.0 - published on 29 Oct 2024 doi:10.25334/DEF9-1J96 - cite this

Keywords

  1. Immunology
  2. PCR
  3. COVID19
  4. SARS-CoV-2
  5. structure and function
  6. ImmunoReach
  7. antigen-antibody interaction
  8. Information Flow
  9. Antigen test
  10. Antibody test

Alignments

  1. Resource Type
  2. Audience Level
  3. Open Science and Education Practices Ontology
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Description

This is a poster presented by Dr. Sean Coleman at the 2023 American Society for Microbiology Conference for Undergraduate Educators. The poster illustrates how the activity was implemented and includes preliminary data on the effectiveness of the activity in meeting the learning outcomes.

References:

1. The original activity can be found here:

Basta, H., Coleman, S., Pavlova, I. V., Shah, A. (2023). When tests disagree, how do I know if I have COVID-19?. ImmunoReach: Interdisciplinary Immunology Education Consortium, QUBES Educational Resources. doi:10.25334/JEB5-Y738

2. The cover art image was created by Dr. Sumali Pandey using www.biorender.com

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