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    Data Analysis and Cancer
    This is a flipped classroom approach, students will learn the basic content about cell-signaling, p53, and transcription factors before class. During class students will focus on data analysis...

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymolecular biologydata interpretationBiological Data Analysiscell cyclemacromoleculesGenetic diseaseCell signaling

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    Cell Cycle and Mitosis
    This module introduces activities that allow students to walk through the cell cycle and mitotic cell division processes. As part of the activities, students learn about and apply knowledge of...

    Keywords: introductory biologyQuantitative reasoningInterdisciplinary STEMquantitative biologyinterdisciplinaryquantitative skillscell functioncell cyclemitosisCell DivisionMitotic Indexcalculating meanstumorNIQBC2. Data and GraphsC4. mathematical modelsC3. Statistical Analysisstandard errormitotic phaseinterphase

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    CYTOSKELETON - Microtubule Dynamics in the Cell Cycle
    This module contains exercises designed to help upper-level cell biology students understand the dynamics of microtubule polymerization and depolymerization within the cell cycle and how cancer...

    Keywords: cell biologyQuantitative reasoningInterdisciplinary STEMInterpreting GraphsCytoskeletonScientific reasoningdimensional analysisNIQBC2. Data and GraphsC6. Quantitative LanguageC1. Numeracy

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    A STEAM Approach to Investigating the Hydrologic Cycle
    The purpose of this experiential lesson is to teach introductory to mid-level undergraduate students how to make detailed hydrologic field observations into a conceptual model using a painting...

    Keywords: modelinghydrologyfield-based learningSTEAM curriculumhydrogeologyhydrologic cycle

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    Targeting Infected Cells for Immune Defense
    This animation shows how a cell infected by a virus signals cytotoxic T cells to destroy itself.

    Keywords: Resources @ HHMI - BioInteractiveimmune systemAnatomy & PhysiologyCell communication

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    DataONE Module 02: Data Sharing
    Data sharing in the context of the data life cycle, the value of sharing data, concerns about sharing data, and methods and best practices for sharing data.

    Keywords: Data Discovery RCNmoduledatain-class activityHandoutproblem setdata managementDataONEPresentation

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    Enzyme Kinetics: How Quickly Can Acetylcholinesterase Break Up Your Thoughts?
    This module contains exercises designed to help upper-level cell biology students understand the common graphical methods used to evaluate enzyme activity and to see the impact of inhibitors on...

    Keywords: cell biologyQuantitative reasoninginterdisciplinarylinear modelsInterpreting GraphsNIQBC2. Data and GraphsC4. mathematical modelsnonlinear models

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    Hemoglobin bioinformatics
    This is an introduction to bioinformatics using hemoglobin as an example. The worksheets introduce students to resources to explore the DNA, RNA and polypeptide linear structure with a brief...

    Keywords: bioinformaticsHemoglobinBLASTsickle cell diseaseMolecular Case StudyClustal OmegaMolCaseNet

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    Making “sense” out of surface area to volume relationships
    Using a multimodal approach, the non-linear aspect of the surface area to volume relationship is explored. Students use their their senses of taste and sight to determine how smaller cells and...

    Keywords: active learningintroductory biologycell biologyquantitative skillskinesthetic learningLDC2023

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    Electrical Activity of Neurons
    This tutorial describes how neurons generate action potentials, and how scientists measure neuronal activity and record the firing of individual neurons.

    Keywords: Resources @ HHMI - BioInteractiveAnatomy & PhysiologyNervous systemCell communication

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    Cell ploidy made simple: Resources for students and instructors
    The concept of cell ploidy can be challenging for students to grasp. This resource includes a short, informal instructional video and a worksheet/set of clicker questions combo that allows students...

    Keywords: meiosismitosis1n2nploidyhaploiddiploid

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    The p53 Gene and Cancer
    This tutorial describes the structure and function of the p53 protein, how its activity is regulated in cells, and how mutant versions of p53 can lead to cancer.

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymolecular biologymacromoleculesGenetic disease

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    DataONE Module 01: Why Data Management?
    Trends in data collection, storage and loss, the importance and benefits of data management, and an introduction to the data life cycle.

    Keywords: moduledatain-class activityHandoutproblem setdata managementDataONE

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    DataONE Module 03: Data Management Planning
    Benefits of a data management plan (DMP), DMP components, tools for creating a DMP, NSF DMP information, and a sample DMP.

    Keywords: moduledatain-class activityHandoutproblem setdata managementDataONEPresentation

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    Polyploidapalooza: Exploring the diversity and evolution of polyploid plants and animals
    This series of modules explores the complex world of polyploidy, including species formation, cell division, evolution, conservation, and economic importance. We focus on polyploidy across the...

    Keywords: Evolutionconservationnatural historyCell DivisionhybridizationPolyploidygenome duplicationallopolyploidyautopolyploidy

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    Using the IEDB to Predict Proteasomal Cleavage Events and T-cell Epitopes
    Research experiences provide a valuable view into the world of science and a great way to explore new fields and careers while developing critical thinking skills. The development and maintenance...

    Keywords: biologydatabaseImmunologydata sciencebioinformaticsBiotechnologyt-cellengineeringantibodyBioengineeringAntibody EngineeringlymphocytesProteinNetChopepitopeIEDBB-cellProteasomeProteasomal Cleavage

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    Learn Biological Sciences and Mathematics through cellular respiration, photosynthesis and primary productivity.
    Photosynthesis is a process by which plants synthesize glucose and oxygen in presence of sunlight through light dependent reactions by utilization of sunlight, water to synthesize oxygen, ATP and...

    Keywords: mathematicssimulationThe Analysis of Biological DataMetabolic Pathwaysprocess of sciencephotosynthesisqbccBiological ScienceshypothesisCellular Respirationprimary productivity

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    Morphological identification of mosquitoes through microscopic observation
    Scientific research is integrated into various stages of student learning, but hands-on involvement in the research process typically begins at the university level. This module aims to engage high...

    Keywords: modulebiologyproject based learningmosquitoScientific researchMicroscope usedigital accessibility

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    Paleoclimate and Ocean Biogeochemistry (Project EDDIE)
    This module guides students in an examination of how surface ocean productivity relates to global climate on glacial-interglacial timescales and how the availability of ocean nutrients can be...

    Keywords: productivitycarbon cyclebiological pump

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    Water Quality Investigation (Project EDDIE)
    This multi-part module aims to help you learn about water quality implications by understanding the variability of concentrations of nitrate in stream water through the evaluation of real-time data...

    Keywords: dataExcelwaternitrogenUSGSProject EDDIEnitrogen cycle

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